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Stock-Based Compensation - Assumptions Used for Fair Value of Stock Options (Details) - Stock options
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Assumptions used to determine fair value of stock options    
Expected dividend yield 0.00% 0.00%
Risk-free rate, minimum 0.70% 0.50%
Risk-free rate, maximum 1.70% 1.90%
Volatility, minimum 118.00% 111.00%
Volatility, maximum 128.00% 129.00%
Minimum    
Assumptions used to determine fair value of stock options    
Expected option term 6 years 1 month 6 days 6 years 1 month 6 days
Maximum    
Assumptions used to determine fair value of stock options    
Expected option term 10 years 10 years