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Related Party Transactions (Details) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Related party transactions      
Outstanding receivable $ 51 $ 75  
Tepha, Inc.
     
Related party transactions      
License and royalty revenue 149 149 444
Outstanding receivable $ 51 $ 75