X0306 4 2022-06-24 0 0001120193 NASDAQ, INC. NDAQ 0001736565 SKULE JEREMY 151 W. 42ND STREET NEW YORK NY 10036 0 1 0 0 Executive Vice President Common stock, par value $0.01 per share 2022-06-24 4 S 0 1400 160.00 D 21504 D The sales reported were effected pursuant to a Rule 10b5-1 trading plan. Represents (i) 4,496 shares or units of unvested restricted stock (ii) 16,281 shares underlying PSUs, all of which are vested and (iii) 727 shares purchased under the Employee Stock Purchase Plan. /s/ Alex Kogan, by power of attorney 2022-06-28