X0306 4 2021-10-13 0 0001120193 NASDAQ, INC. NDAQ 0001736565 SKULE JEREMY 151 W. 42ND STREET NEW YORK NY 10036 0 1 0 0 Executive Vice President Common stock, par value $0.01 per share 2021-10-13 4 S 0 865 197.68 D 16324 D The sales reported were effected pursuant to a Rule 10b5-1 trading plan. Represents (i) 3,607 shares or units of restricted stock, of which none are vested, (ii) 11,990 shares underlying PSUs, all of which are vested and (iii) 727 shares purchased under the Employee Stock Purchase Plan. /s/ Jeffrey S. Davis, by power of attorney 2021-10-14