The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M COMPANY COM 88579Y101 759 5,040 SH   SOLE   5,040 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 15,448 433,325 SH   SOLE   433,325 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 2,884 118,450 SH   SOLE   118,450 0 0
ALIBABA GROUP HOLDING-SP SPON ADR 01609W102 6,713 82,610 SH   SOLE   82,610 0 0
ALPHABET INC CAP STK CAP STK CL C 02079K107 9,952 13,115 SH   SOLE   13,115 0 0
ALPHABET INC CAP STK CAP STK CL A 02079K305 4,302 5,530 SH   SOLE   5,530 0 0
AMAZON.COM INC COM 023135106 337 500 SH   SOLE   500 0 0
AMERICAN AIRLINES GROUP INC COM 02376R102 5,769 136,225 SH   SOLE   136,225 0 0
APPLE COMPUTER INC COM 037833100 17,659 167,769 SH   SOLE   167,769 0 0
ATT INC COM 00206R102 9,118 264,993 SH   SOLE   264,993 0 0
AURIS MEDICAL HOLDING AG CHF0. COM H03579101 251 51,500 SH   SOLE   51,500 0 0
BAIDU.COM SPON ADR REPA 056752108 1,228 6,500 SH   SOLE   6,500 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 746 5,650 SH   SOLE   5,650 0 0
BERKSHIRE HATHAWAY INC CL-A CL A 084670108 395 2 SH   SOLE   2 0 0
BLACKROCK MUN TARGET TERM TR COM SHS BEN IN 09257P105 1,499 69,500 SH   SOLE   69,500 0 0
BLACKROCK MUNI INTER DURATION COM 09253X102 3,471 245,000 SH   SOLE   245,000 0 0
BOEING CO COM 097023105 3,086 21,345 SH   SOLE   21,345 0 0
BUNGE LIMITED COM STK USD0.01 COM G16962105 409 6,000 SH   SOLE   6,000 0 0
CARRIZO COM 144577103 207 7,000 SH   SOLE   7,000 0 0
CBS CORP NEW CLASS B CL B 124857202 8,767 186,025 SH   SOLE   186,025 0 0
CELGENE CORP COM 151020104 9,455 78,950 SH   SOLE   78,950 0 0
CEMPRA INC COM 15130J109 3,494 112,250 SH   SOLE   112,250 0 0
CHARTER COMMUNICATIONS INC CL A NEW 16117M305 915 5,000 SH   SOLE   5,000 0 0
CHICAGO BRIDGE IRON COMPANY COM 167250109 1,285 32,976 SH   SOLE   32,976 0 0
CISCO SYSTEMS COM 17275R102 207 7,625 SH   SOLE   7,625 0 0
COCA-COLA FEMSA S.A.B. DE C.V SPON ADR REP L 191241108 495 7,000 SH   SOLE   7,000 0 0
COLGATE PALMOLIVE CO COM 194162103 266 4,000 SH   SOLE   4,000 0 0
COMCAST CL A VTG CL A 20030N101 2,991 53,004 SH   SOLE   53,004 0 0
CVS CAREMARK CORP COM 126650100 1,075 11,000 SH   SOLE   11,000 0 0
DEERE CO COM 244199105 381 5,000 SH   SOLE   5,000 0 0
DISCOVERY COMMUNICATIONS INC N COM SER A 25470F104 4,173 156,425 SH   SOLE   156,425 0 0
EMC CORPORATION COM 268648102 1,284 50,000 SH   SOLE   50,000 0 0
EOG RESOURCES INC COM 26875P101 1,662 23,480 SH   SOLE   23,480 0 0
EXACT SCIENCES CORP COM 30063P105 1,183 128,200 SH   SOLE   128,200 0 0
EXPRESS SCRIPTS HLDG CO COM COM 30219G108 2,185 25,000 SH   SOLE   25,000 0 0
FEDEX CORP COM 31428X106 372 2,500 SH   SOLE   2,500 0 0
FIREEYE INC COM 31816Q101 5,387 259,750 SH   SOLE   259,750 0 0
GENERAL ELECTRIC CO COM 369604103 2,959 95,000 SH   SOLE   95,000 0 0
GILEAD SCIENCES COM 375558103 12,693 125,440 SH   SOLE   125,440 0 0
HEXCEL COM 428291108 3,457 74,425 SH   SOLE   74,425 0 0
HONEYWELL INTL INC COM 438516106 517 5,000 SH   SOLE   5,000 0 0
ISHARES SP 500 INDEX FUND CORE SP 500 E 464287200 307 1,500 SH   SOLE   1,500 0 0
ISHARES SP 500/BARRA GROWTH I SP 500 GRWT E 464287309 254 2,200 SH   SOLE   2,200 0 0
JOHNSON JOHNSON COM 478160104 534 5,200 SH   SOLE   5,200 0 0
JP MORGAN CHASE COM 46625H100 765 11,589 SH   SOLE   11,589 0 0
LOWES COMPANIES COM 548661107 775 10,200 SH   SOLE   10,200 0 0
MARINUS PHARMACEUTICALS INC CO COM 56854Q101 106 14,000 SH   SOLE   14,000 0 0
MASTERCARD INC CL A 57636Q104 584 6,000 SH   SOLE   6,000 0 0
MICROSOFT CORP COM 594918104 443 8,000 SH   SOLE   8,000 0 0
MONSANTO CO NEW COM 61166W101 985 10,000 SH   SOLE   10,000 0 0
NATIONAL GRID NEW ADR EACH REP SPON ADR NEW 636274300 1,446 20,800 SH   SOLE   20,800 0 0
NEKTAR THERAPEUTICS COM 640268108 10,083 598,400 SH   SOLE   598,400 0 0
NOVARTIS AG- SPON ADR 66987V109 2,292 26,650 SH   SOLE   26,650 0 0
NOVAVAX INC COM 670002104 5,417 645,650 SH   SOLE   645,650 0 0
NXP SEMICONDUCTORS N V COM N6596X109 5,624 66,760 SH   SOLE   66,760 0 0
ORACLE CORPORATION COM 68389X105 7,538 206,375 SH   SOLE   206,375 0 0
OTONOMY INC COM 68906L105 4,274 154,025 SH   SOLE   154,025 0 0
OUTFRONT MEDIA INC COM ISIN #U COM 69007J106 1,583 72,529 SH   SOLE   72,529 0 0
PFIZER INC COM 717081103 322 10,000 SH   SOLE   10,000 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 8,086 157,180 SH   SOLE   157,180 0 0
POTASH CORP SASK INC COM COM 73755L107 231 13,500 SH   SOLE   13,500 0 0
PRICELINE GROUP INC THE COM NEW 741503403 8,130 6,377 SH   SOLE   6,377 0 0
PROCTOR GAMBLE COM 742718109 246 3,100 SH   SOLE   3,100 0 0
PROOFPOINT INC COM 743424103 5,833 89,735 SH   SOLE   89,735 0 0
PRUDENTIAL FINANCIAL INC COM 744320102 4,688 57,587 SH   SOLE   57,587 0 0
QUALCOMM INC COM 747525103 3,000 60,020 SH   SOLE   60,020 0 0
RESTORATION HARDWARE HOLDING COM 761283100 5,343 67,255 SH   SOLE   67,255 0 0
RITE AID CORPORATION COM 767754104 862 110,000 SH   SOLE   110,000 0 0
SAGE THERAPEUTICS INC COM COM 78667J108 1,029 17,655 SH   SOLE   17,655 0 0
SKECHERS USA INC- CL A 830566105 6,993 231,500 SH   SOLE   231,500 0 0
SOCIEDAD QUIMICA MINERA DE CH SPON ADR SER B 833635105 532 28,000 SH   SOLE   28,000 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 2,943 293,500 SH   SOLE   293,500 0 0
THE WALT DISNEY CO COM DISNEY 254687106 2,376 22,620 SH   SOLE   22,620 0 0
TIME WARNER CABLE INC COM COM 88732J207 217 1,171 SH   SOLE   1,171 0 0
TIME WARNER INC NEW COM NEW 887317303 7,725 119,466 SH   SOLE   119,466 0 0
UNITED PARCEL SERVICE INC CL B 911312106 240 2,500 SH   SOLE   2,500 0 0
UNITED TECHNOLOGIES CORP COM COM 913017109 230 2,400 SH   SOLE   2,400 0 0
VERIZON COMMUNICATIONS COM 92343V104 374 8,106 SH   SOLE   8,106 0 0
VISA INC COM COM CL A 92826C839 550 7,100 SH   SOLE   7,100 0 0
WALGREENS BOOTS ALLIANCE INC C COM 931427108 851 10,000 SH   SOLE   10,000 0 0