The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M COMPANY COM 88579Y101 746 5,500 SH   SOLE   5,500 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 13,582 558,250 SH   SOLE   558,250 0 0
APPLE COMPUTER INC COM 037833100 13,843 25,792 SH   SOLE   25,792 0 0
ATT INC COM 00206R102 6,954 198,307 SH   SOLE   198,307 0 0
BAIDU.COM SPON ADR REPA 056752108 761 5,000 SH   SOLE   5,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 706 5,650 SH   SOLE   5,650 0 0
BERKSHIRE HATHAWAY INC CL-A CLA 084670108 749 4 SH   SOLE   4 0 0
BHP BILLITON PLC SPONS ADR EAC SPON ADR 05545E209 308 5,000 SH   SOLE   5,000 0 0
BLACKROCK MUNI INTER DURATION COM 09253X102 1,540 108,500 SH   SOLE   108,500 0 0
BOEING CO COM 097023105 2,672 21,300 SH   SOLE   21,300 0 0
BUNGE LIMITED COM STK USD0.01 COM G16962105 477 6,000 SH   SOLE   6,000 0 0
CARRIZO COM 144577103 1,892 35,400 SH   SOLE   35,400 0 0
CATERPILLAR INC COM 149123101 347 3,500 SH   SOLE   3,500 0 0
CELGENE CORP COM 151020104 8,787 62,950 SH   SOLE   62,950 0 0
CHARTER COMMUNICATIONS INC CL A NEW 16117M305 616 5,000 SH   SOLE   5,000 0 0
CHECK POINT SOFTWARE TECHNOLOG ORD M22465104 7,277 107,610 SH   SOLE   107,610 0 0
CHEGG INC COM 163092109 2,070 295,800 SH   SOLE   295,800 0 0
CHICAGO BRIDGE IRON COMPANY COM 167250109 2,838 32,576 SH   SOLE   32,576 0 0
CISCO SYSTEMS COM 17275R102 215 9,625 SH   SOLE   9,625 0 0
COACH INC COM 189754104 5,614 113,050 SH   SOLE   113,050 0 0
COCA-COLA FEMSA S.A.B. DE C.V SPON ADR REP L 191241108 1,266 12,000 SH   SOLE   12,000 0 0
COLGATE PALMOLIVE CO COM 194162103 259 4,000 SH   SOLE   4,000 0 0
COMCAST CL A VTG CLA 20030N101 2,612 52,217 SH   SOLE   52,217 0 0
CONCHO RESOURCES COM 20605P101 7,474 61,020 SH   SOLE   61,020 0 0
CVS CAREMARK CORP COM 126650100 598 8,000 SH   SOLE   8,000 0 0
DEERE CO COM 244199105 563 6,207 SH   SOLE   6,207 0 0
EBAY COM 278642103 4,968 89,950 SH   SOLE   89,950 0 0
EMC CORPORATION COM 268648102 9,091 331,700 SH   SOLE   331,700 0 0
EOG RESOURCES INC COM 26875P101 2,303 11,740 SH   SOLE   11,740 0 0
EXPRESS SCRIPTS HLDG CO COM COM 30219G108 1,877 25,000 SH   SOLE   25,000 0 0
FEDEX CORP COM 31428X106 331 2,500 SH   SOLE   2,500 0 0
GENERAL ELECTRIC CO COM 369604103 10,054 388,350 SH   SOLE   388,350 0 0
GILEAD SCIENCES COM 375558103 11,923 168,275 SH   SOLE   168,275 0 0
GOODRICH PETROLEUM CORP COM 382410405 7,234 457,300 SH   SOLE   457,300 0 0
GOOGLE INC CLA 38259P508 5,962 5,350 SH   SOLE   5,350 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 4,980 392,050 SH   SOLE   392,050 0 0
HARRIS HARRIS GROUP INC COM 413833104 34 10,000 SH   SOLE   10,000 0 0
HONEYWELL INTL INC COM 438516106 463 5,000 SH   SOLE   5,000 0 0
INFOBLOX INC COM 45672H104 627 31,285 SH   SOLE   31,285 0 0
INTEL CORP COM 458140100 3,903 151,209 SH   SOLE   151,209 0 0
ISHARES SP 500 INDEX FUND CORE SP 500 E 464287200 291 1,550 SH   SOLE   1,550 0 0
ISHARES SP 500/BARRA GROWTH I SP 500 GRWT E 464287309 219 2,200 SH   SOLE   2,200 0 0
ISHARES TR IBOXX $ HIGH YIE COM 464288513 1,162 12,316 SH   SOLE   12,316 0 0
JOHNSON JOHNSON COM 478160104 491 5,000 SH   SOLE   5,000 0 0
KERYX BIOPHARMACEUTICALS COM 492515101 15,605 915,800 SH   SOLE   915,800 0 0
LOWES COMPANIES COM 548661107 596 12,200 SH   SOLE   12,200 0 0
MAGNUM HUNTER RES CORP DEL COM COM 55973B102 14,619 1,719,900 SH   SOLE   1,719,900 0 0
MICROSOFT CORP COM 594918104 561 13,700 SH   SOLE   13,700 0 0
MONSANTO CO NEW COM 61166W101 1,137 10,000 SH   SOLE   10,000 0 0
NATIONAL GRID NEW ADR EACH REP SPON ADR NEW 636274300 1,429 20,800 SH   SOLE   20,800 0 0
NEKTAR THERAPEUTICS COM 640268108 1,580 130,400 SH   SOLE   130,400 0 0
NOVARTIS AG- SPON ADR 66987V109 2,265 26,650 SH   SOLE   26,650 0 0
NOVAVAX INC COM 670002104 2,296 506,950 SH   SOLE   506,950 0 0
NPS PHARMACEUTICALS INC COM 62936P103 12,695 424,175 SH   SOLE   424,175 0 0
PEPSICO INC COM 713448108 250 3,000 SH   SOLE   3,000 0 0
PHARMACYCLICS INC COM 716933106 3,316 33,095 SH   SOLE   33,095 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 2,769 106,930 SH   SOLE   106,930 0 0
POTASH CORP SASK INC COM COM 73755L107 488 13,500 SH   SOLE   13,500 0 0
POWERSHARES ETF TR II SENIOR LN PORT 73936Q769 1,095 44,150 SH   SOLE   44,150 0 0
PROCERA NETWORKS INC COM NEW 74269U203 3,615 348,000 SH   SOLE   348,000 0 0
PROCTOR GAMBLE COM 742718109 282 3,500 SH   SOLE   3,500 0 0
QUALCOMM INC COM 747525103 10,415 132,072 SH   SOLE   132,072 0 0
ROSETTA RESOURCES INC COM 777779307 4,117 88,400 SH   SOLE   88,400 0 0
SANCHEZ ENERGY CORP COM 79970Y105 7,766 262,100 SH   SOLE   262,100 0 0
SIMON PPTY GRP INC COM 828806109 213 1,300 SH   SOLE   1,300 0 0
SM ENERGY CO COM COM 78454L100 534 7,500 SH   SOLE   7,500 0 0
SOCIEDAD QUIMICA MINERA DE CH SPON ADR SER B 833635105 904 28,500 SH   SOLE   28,500 0 0
SYNGENTA AG SPON ADR 87160A100 227 3,000 SH   SOLE   3,000 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 3,611 331,600 SH   SOLE   331,600 0 0
THE WALT DISNEY CO COM DISNEY 254687106 1,641 20,500 SH   SOLE   20,500 0 0
TIME WARNER INC NEW COM NEW 887317303 4,443 68,016 SH   SOLE   68,016 0 0
TWITTER INC COM USD0.000005 COM 90184L102 238 5,100 SH   SOLE   5,100 0 0
UNITED PARCEL SERVICE INC CL B 911312106 243 2,500 SH   SOLE   2,500 0 0
UNITED TECHNOLOGIES CORP COM COM 913017109 280 2,400 SH   SOLE   2,400 0 0
XOMA CORP COM 98419J107 60 10,000 SH   SOLE   10,000 0 0
YANDEX N.V. COM USD0.01 CL SHS CL A N97284108 784 26,000 SH   SOLE   26,000 0 0