The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M COMPANY COM 88579Y101 701 5,000 SH   SOLE   5,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 13,480 539,450 SH   SOLE   539,450 0 0
ANTARES PHARMA INC COM 036642106 2,387 534,000 SH   SOLE   534,000 0 0
APPLE COMPUTER INC COM 037833100 13,474 24,018 SH   SOLE   24,018 0 0
ATT INC COM 00206R102 6,634 188,700 SH   SOLE   188,700 0 0
BAIDU.COM SPON ADR REPA 056752108 889 5,000 SH   SOLE   5,000 0 0
BERKSHIRE HATHAWAY INC DEL CL CL B NEW 084670702 669 5,650 SH   SOLE   5,650 0 0
BERKSHIRE HATHAWAY INC CL-A CLA 084670108 711 4 SH   SOLE   4 0 0
BHP BILLITON PLC SPONS ADR EAC SPON ADR 05545E209 310 5,000 SH   SOLE   5,000 0 0
BOEING CO COM 097023105 2,907 21,300 SH   SOLE   21,300 0 0
BP PRUDHOE BAY ROYALTY TR UNIT BEN INT 055630107 318 4,000 SH   SOLE   4,000 0 0
BUNGE LIMITED COM STK USD0.01 COM G16962105 492 6,000 SH   SOLE   6,000 0 0
CARRIZO COM 144577103 5,027 112,300 SH   SOLE   112,300 0 0
CATERPILLAR INC COM 149123101 272 3,000 SH   SOLE   3,000 0 0
CELGENE CORP COM 151020104 11,481 67,950 SH   SOLE   67,950 0 0
CHARTER COMMUNICATIONS INC CL A NEW 16117M305 683 5,000 SH   SOLE   5,000 0 0
CHECK POINT SOFTWARE TECHNOLOG ORD M22465104 6,979 108,210 SH   SOLE   108,210 0 0
CHICAGO BRIDGE IRON COMPANY COM 167250109 2,708 32,576 SH   SOLE   32,576 0 0
COACH INC COM 189754104 5,693 101,430 SH   SOLE   101,430 0 0
COCA-COLA FEMSA S.A.B. DE C.V SPON ADR REP L 191241108 1,461 12,000 SH   SOLE   12,000 0 0
COLGATE PALMOLIVE CO COM 194162103 260 4,000 SH   SOLE   4,000 0 0
COMCAST CL A VTG CLA 20030N101 2,713 52,217 SH   SOLE   52,217 0 0
CONCHO RESOURCES COM 20605P101 6,600 61,120 SH   SOLE   61,120 0 0
CVS CAREMARK CORP COM 126650100 572 8,000 SH   SOLE   8,000 0 0
DEERE CO COM 244199105 538 5,900 SH   SOLE   5,900 0 0
EBAY COM 278642103 5,053 92,100 SH   SOLE   92,100 0 0
EMC CORPORATION COM 268648102 8,320 330,850 SH   SOLE   330,850 0 0
EOG RESOURCES INC COM 26875P101 4,837 28,825 SH   SOLE   28,825 0 0
EXPRESS SCRIPTS HLDG CO COM COM 30219G108 1,756 25,000 SH   SOLE   25,000 0 0
FEDEX CORP COM 31428X106 359 2,500 SH   SOLE   2,500 0 0
GENERAL ELECTRIC CO COM 369604103 2,775 99,030 SH   SOLE   99,030 0 0
GILEAD SCIENCES COM 375558103 12,101 161,145 SH   SOLE   161,145 0 0
GOOGLE INC CLA 38259P508 6,107 5,450 SH   SOLE   5,450 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 3,207 214,000 SH   SOLE   214,000 0 0
HARRIS HARRIS GROUP INC COM 413833104 29 10,000 SH   SOLE   10,000 0 0
HONEYWELL INTL INC COM 438516106 456 5,000 SH   SOLE   5,000 0 0
INTEL CORP COM 458140100 4,171 160,714 SH   SOLE   160,714 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 2,631 38,535 SH   SOLE   38,535 0 0
INTL BUSINESS MACH COM 459200101 2,157 11,500 SH   SOLE   11,500 0 0
ISHARES SP 500 INDEX FUND CORE SP 500 E 464287200 334 1,800 SH   SOLE   1,800 0 0
ISHARES SP500/BARRA GROWTH IN SP 500 GRWT E 464287309 217 2,200 SH   SOLE   2,200 0 0
JOHNSON JOHNSON COM 478160104 457 5,000 SH   SOLE   5,000 0 0
KERYX BIOPHARMACEUTICALS COM 492515101 11,531 890,500 SH   SOLE   890,500 0 0
KINDER MORGAN ENERGY PARTNERS COM 494550106 1,209 15,000 SH   SOLE   15,000 0 0
LIFELOCK COM 53224V100 1,475 89,900 SH   SOLE   89,900 0 0
LOWES COMPANIES COM 548661107 639 12,905 SH   SOLE   12,905 0 0
MAGNUM HUNTER RES CORP DEL COM COM 55973B102 12,142 1,661,100 SH   SOLE   1,661,100 0 0
MICROSOFT CORP COM 594918104 493 13,200 SH   SOLE   13,200 0 0
MONSANTO CO NEW COM 61166W101 1,165 10,000 SH   SOLE   10,000 0 0
NATIONAL GRID NEW ADR EACH REP SPON ADR NEW 636274300 1,685 25,800 SH   SOLE   25,800 0 0
NOVARTIS AG- SPON ADR 66987V109 2,142 26,650 SH   SOLE   26,650 0 0
NOVAVAX INC COM 670002104 413 80,700 SH   SOLE   80,700 0 0
NPS PHARMACEUTICALS INC COM 62936P103 16,680 549,425 SH   SOLE   549,425 0 0
ONEOK PARTNERS L P UNIT LTD P UT LTD PARTNER 68268N103 473 9,000 SH   SOLE   9,000 0 0
PEPSICO INC COM 713448108 248 3,000 SH   SOLE   3,000 0 0
PLUM CREEK TIMBER COINC COM 729251108 232 5,000 SH   SOLE   5,000 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 1,117 43,400 SH   SOLE   43,400 0 0
POTASH CORP SASK INC COM COM 73755L107 444 13,500 SH   SOLE   13,500 0 0
PROCERA NETWORKS INC COM NEW 74269U203 5,114 340,500 SH   SOLE   340,500 0 0
PROCTOR GAMBLE COM 742718109 508 6,250 SH   SOLE   6,250 0 0
QUALCOMM INC COM 747525103 10,063 135,532 SH   SOLE   135,532 0 0
RAYONIER INC COM 754907103 321 7,625 SH   SOLE   7,625 0 0
ROSETTA RESOURCES INC COM 777779307 4,157 86,550 SH   SOLE   86,550 0 0
SANCHEZ ENERGY CORP COM 79970Y105 6,313 257,600 SH   SOLE   257,600 0 0
SIMON PPTY GRP INC COM 828806109 257 1,691 SH   SOLE   1,691 0 0
SM ENERGY CO COM COM 78454L100 4,388 52,800 SH   SOLE   52,800 0 0
SOCIEDAD QUIMICA MINERA DE CH SPON ADR SER B 833635105 737 28,500 SH   SOLE   28,500 0 0
SYNGENTA AG SPON ADR 87160A100 239 3,000 SH   SOLE   3,000 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 3,859 285,500 SH   SOLE   285,500 0 0
THE WALT DISNEY CO COM DISNEY 254687106 1,566 20,500 SH   SOLE   20,500 0 0
TIME WARNER INC NEW COM NEW 887317303 325 4,666 SH   SOLE   4,666 0 0
TWITTER INC COM USD0.000005 COM 90184L102 324 5,100 SH   SOLE   5,100 0 0
UNITED PARCEL SERVICE INC CL B CL B 911312106 262 2,500 SH   SOLE   2,500 0 0
UNITED TECHNOLOGIES CORP COM COM 913017109 273 2,400 SH   SOLE   2,400 0 0
VODAFONE GROUP SPON ADR REP 10 SPON ADR NEW 92857W209 2,963 75,400 SH   SOLE   75,400 0 0
XOMA CORP COM 98419J107 2,530 376,000 SH   SOLE   376,000 0 0
YANDEX N.V. COM USD0.01 CL SHS CL A N97284108 1,147 26,600 SH   SOLE   26,600 0 0