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Stockholders' Equity (Deficit) (Narrative) (Details) (USD $)
0 Months Ended 3 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended
Apr. 09, 2014
Mar. 31, 2014
Mar. 31, 2013
Mar. 31, 2012
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Jun. 20, 2014
Apr. 30, 2013
Jan. 01, 2014
Feb. 28, 2013
Nov. 05, 2014
Apr. 16, 2013
Oct. 23, 2013
Apr. 10, 2013
Feb. 28, 2011
May 27, 2014
Apr. 10, 2010
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Common stock, shares authorized         200,000,000us-gaap_CommonStockSharesAuthorized 200,000,000us-gaap_CommonStockSharesAuthorized                        
Common stock, shares issued         41,031,770us-gaap_CommonStockSharesIssued 26,664,972us-gaap_CommonStockSharesIssued                        
Common stock, shares outstanding         41,031,770us-gaap_CommonStockSharesOutstanding 26,664,972us-gaap_CommonStockSharesOutstanding 1,533,996us-gaap_CommonStockSharesOutstanding                      
Proceeds from initial public offering         $ 225,939,000us-gaap_ProceedsFromIssuanceInitialPublicOffering $ 107,634,000us-gaap_ProceedsFromIssuanceInitialPublicOffering $ 0us-gaap_ProceedsFromIssuanceInitialPublicOffering                      
Warrants to purchase common stock                             41,323us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights      
Stock issued during period, value           107,634,000us-gaap_StockIssuedDuringPeriodValueNewIssues                        
Number of shares outstanding under the plan         1,859,970us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,946,823us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 2,593,423us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber                      
Aggregate intrinsic value of options outstanding         18,400,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue                          
Aggregate intrinsic value of options exercisable           20,800,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1                        
Intrinsic value of options exercised         30,400,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue 12,400,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue 18,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue                      
Share-based compensation, award vesting period 15 months                                  
Tax benefit from stock options exercised         0us-gaap_DeferredTaxExpenseFromStockOptionsExercised   0us-gaap_DeferredTaxExpenseFromStockOptionsExercised                      
Compensation expense, allocated         4,411,000us-gaap_AllocatedShareBasedCompensationExpense 3,071,000us-gaap_AllocatedShareBasedCompensationExpense 1,396,000us-gaap_AllocatedShareBasedCompensationExpense                      
Common stock, capital shares reserved for future issuance         4,678,696us-gaap_CommonStockCapitalSharesReservedForFutureIssuance 5,670,825us-gaap_CommonStockCapitalSharesReservedForFutureIssuance                        
Employees' contribution liabilities, ESPP         296,000us-gaap_EmployeeStockOwnershipPlanESOPCashContributionsToESOP                          
Restricted stock expense         1,400,000us-gaap_RestrictedStockExpense                          
Share-based compensation, cash received from exercise of stock options   5,000,000us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions 1,900,000us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions 14,000us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions                            
The 2012 Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of shares authorized to be granted                             244,717us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2012PlanMember
     
The 2013 Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of shares authorized to be granted                             1,408,450us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
     
Share-based compensation, equity increase               4.00%cmrx_ShareBasedCompensationEvergreenOptionProvisionEquityIncrease
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
2.50%cmrx_ShareBasedCompensationEvergreenOptionProvisionEquityIncrease
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
                 
Share-based compensation, nonvested awards, compensation not yet recognized, stock options         13,900,000us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
                         
Unrecognized compensation costs, period of recognition         3 years 1 month 21 days                          
Common stock, capital shares reserved for future issuance         1,147,526us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
1,681,932us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
                       
The 2013 Employee Stock Purchase Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of shares authorized to be granted         944,599us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
        970,874us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
704,225us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
             
Increase in number of shares authorized to be granted                   266,649us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
               
Number of shares authorized, increase amount                     422,535cmrx_IncreaseDecreaseInNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
             
Percentage of total number of shares of capital stock outstanding                     1.00%cmrx_PercentageOfTotalNumberOfSharesOfCapitalStockOutstanding
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
             
Common stock, capital shares reserved for future issuance         944,599us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
704,225us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
                       
Share-based compensation, maximum employee subscription rate         15.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumEmployeeSubscriptionRate
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
                         
Share-based compensation, shares issued in period         26,275us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
                         
Modified grants | Three individuals                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Additional compensation expense             30,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost
/ us-gaap_PlanNameAxis
= cmrx_ModifiedGrantsMember
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= cmrx_ThreeIndividualsMember
                     
Modified grants | One individual                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Additional compensation expense             300,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost
/ us-gaap_PlanNameAxis
= cmrx_ModifiedGrantsMember
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= cmrx_OneIndividualMember
                     
Increase in compensation expense         1,000,000cmrx_IncreaseDecreaseInCompensationExpense
/ us-gaap_PlanNameAxis
= cmrx_ModifiedGrantsMember
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= cmrx_OneIndividualMember
                         
Maximum | The 2013 Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of shares authorized to be granted         2,816,901us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= cmrx_The2013PlanMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
                         
Maximum | The 2013 Employee Stock Purchase Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Discount from market price, entry date         85.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardDiscountFromMarketPriceOfferingDate
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
                         
Discount from market price, purchase date         85.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardDiscountFromMarketPricePurchaseDate
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
                         
Over-allotment option                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
New issues of stock during period                       547,500us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
1,098,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
         
Offering price per share                       $ 29.00us-gaap_SharesIssuedPricePerShare
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
$ 14.00us-gaap_SharesIssuedPricePerShare
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
         
Public offering underwriting discounts and commissions                         1,100,000cmrx_PublicOfferingUnderwritingDiscountsAndCommissions
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
         
Stock issued during period, value                         14,300,000us-gaap_StockIssuedDuringPeriodValueNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_OverAllotmentOptionMember
         
Secondary offering                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
New issues of stock during period                       4,197,500us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= cmrx_SecondaryOfferingMember
  2,476,995us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= cmrx_SecondaryOfferingMember
       
Series F                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Stock issuance costs                               200,000us-gaap_PaymentsOfStockIssuanceCosts
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesFPreferredStockMember
   
Shares converted in stock conversion                             15,556,091us-gaap_ConversionOfStockSharesConverted1
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesFPreferredStockMember
     
Warrant                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Warrants to purchase common stock                             1,613,395us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementClassOfStockAxis
= us-gaap_WarrantMember
     
Common stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Offering price per share                                 14.22us-gaap_SharesIssuedPricePerShare
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
 
Proceeds from initial public offering                       114,000,000us-gaap_ProceedsFromIssuanceInitialPublicOffering
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
           
Stock issued during period, value           23,000us-gaap_StockIssuedDuringPeriodValueNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
                       
Common stock, capital shares reserved for future issuance         1,859,970us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
1,946,823us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
                       
Over-allotment option | Common stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
New issues of stock during period                                 1,095,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_OverAllotmentOptionMember
 
IPO                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Offering price per share                                   $ 14.00us-gaap_SharesIssuedPricePerShare
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
Proceeds from initial public offering                             93,300,000us-gaap_ProceedsFromIssuanceInitialPublicOffering
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
     
Public offering underwriting discounts and commissions                             7,100,000cmrx_PublicOfferingUnderwritingDiscountsAndCommissions
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
     
Stock issuance costs                             2,100,000us-gaap_PaymentsOfStockIssuanceCosts
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
     
IPO | Common stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
New issues of stock during period                             7,320,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
  8,395,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
 
Proceeds from initial public offering                                 111,800,000us-gaap_ProceedsFromIssuanceInitialPublicOffering
/ us-gaap_StatementClassOfStockAxis
= us-gaap_CommonStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_IPOMember
 
Common Stock | The 2013 Employee Stock Purchase Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Common stock, capital shares reserved for future issuance         970,874us-gaap_CommonStockCapitalSharesReservedForFutureIssuance
/ us-gaap_PlanNameAxis
= cmrx_The2013EmployeeStockPurchasePlanMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember