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Pay vs Performance Disclosure - USD ($)
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Pay vs Performance Disclosure      
Pay vs Performance Disclosure, Table
Year
Summary Compensation Table Total for PEO ($)(1)(2)
Compensation Actually Paid to PEO ($)(3)
Average Summary Compensation Table Total for non-PEO NEOs ($)(1)
Average Compensation Actually Paid to non-PEO NEOs ($)(3)
Value of Initial Fixed $100 Investment Based On Total Stockholder Return ($)(4)
Net Income (loss) ($ in thousands)(5)
PEO1PEO2PEO1PEO2
20231,486,6711,312,421(85)764,028862,824461,716$19.88(82,095)
20224,061,403—(1,719,739)—1,572,368(313,960)$38.51172,167
20216,026,822—6,554,832—2,203,6532,312,710$133.13(173,236)
    
Company Selected Measure Name Net income (loss)    
Named Executive Officers, Footnote PEO1 for each year reported was Mike Sherman, PEO2 for 2023 was Mike Andriole. The non-PEO NEOs for 2023 were Michael A. Alrutz, Ph.D., J.D. and Allen S. Melemed, M.D. The non-PEO NEOs for 2022 and 2021 were Mike Andriole and Allen S. Melemed, M.D    
Adjustment To PEO Compensation, Footnote The reported dollar amounts represent the amount of “compensation actually paid” to PEO1 and PEO2 and the average amount of “compensation actually paid” to our non-PEO NEOs, respectively, as computed in accordance with Item 402(v) of Regulation S-K. The dollar amounts do not reflect the actual amount of compensation earned by or paid to our NEOs during the applicable year. In accordance with the requirements of Item 402(v) of Regulation S-K, the following adjustments were made to the reported total compensation for each year to determine the compensation actually paid:
Summary Compensation Table TotalPEO1PEO2Average of Non-PEO NEOs
202320232023
1,486,6711,312,421862,824
     Deduct: Grant Date Fair Value of Equity Awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table 961,623492,416244,105
     Add: Year-End Fair Value of Equity Awards Granted in the Year353,236246,83089,668
     Add: Change in Fair Value of Outstanding and Unvested Equity Awards Granted in Prior Fiscal Year(634,755)(219,881)(176,242)
     Add: Change in Fair Value of Equity Awards Granted in Prior Years that Vested in the Year(342,262)(117,073)(95,470)
     Add: Change in Fair Value of Equity Awards Granted and Vested in the Year98,64834,14725,041
Compensation Actually Paid (85)764,028461,716
    
Non-PEO NEO Average Total Compensation Amount $ 862,824 $ 1,572,368 $ 2,203,653
Non-PEO NEO Average Compensation Actually Paid Amount $ 461,716 (313,960) 2,312,710
Adjustment to Non-PEO NEO Compensation Footnote The reported dollar amounts represent the amount of “compensation actually paid” to PEO1 and PEO2 and the average amount of “compensation actually paid” to our non-PEO NEOs, respectively, as computed in accordance with Item 402(v) of Regulation S-K. The dollar amounts do not reflect the actual amount of compensation earned by or paid to our NEOs during the applicable year. In accordance with the requirements of Item 402(v) of Regulation S-K, the following adjustments were made to the reported total compensation for each year to determine the compensation actually paid:
Summary Compensation Table TotalPEO1PEO2Average of Non-PEO NEOs
202320232023
1,486,6711,312,421862,824
     Deduct: Grant Date Fair Value of Equity Awards as reported in the “Stock Awards” and “Option Awards” columns in the Summary Compensation Table 961,623492,416244,105
     Add: Year-End Fair Value of Equity Awards Granted in the Year353,236246,83089,668
     Add: Change in Fair Value of Outstanding and Unvested Equity Awards Granted in Prior Fiscal Year(634,755)(219,881)(176,242)
     Add: Change in Fair Value of Equity Awards Granted in Prior Years that Vested in the Year(342,262)(117,073)(95,470)
     Add: Change in Fair Value of Equity Awards Granted and Vested in the Year98,64834,14725,041
Compensation Actually Paid (85)764,028461,716
    
Compensation Actually Paid vs. Total Shareholder Return
COMPENSATION ACTUALLY PAID VS COMPANY TSR

Compensation Paid vs TSR.jpg
    
Compensation Actually Paid vs. Net Income
COMPENSATION ACTUALLY PAID VS NET INCOME

Compensation Paid vs Net Income.jpg
    
Total Shareholder Return Amount $ 19.88 38.51 133.13
Net Income (Loss) $ (82,095,000) 172,167,000 (173,236,000)
Additional 402(v) Disclosure The amounts represent the total compensation reported for each of our PEOs for each corresponding year in the “Total” column of the Summary Compensation Table. Refer to “Executive Compensation—Summary Compensation Table.”TSR is determined based on the value of an initial fixed investment of $100 on December 31, 2020. Cumulative TSR is calculated by dividing the sum of the cumulative amount of dividends for the measurement period, assuming dividend reinvestment, and the difference between the Company’s stock price at the end and the beginning of the measurement period by the Company’s stock price at the beginning of the measurement period.
(5)Net income (loss) attributable to Chimerix as reported in the Company’s consolidated financial statements for the applicable year.
    
Mike Sherman [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount $ 1,486,671 4,061,403 6,026,822
PEO Actually Paid Compensation Amount $ (85) $ (1,719,739) $ 6,554,832
PEO Name Mike Sherman    
Mike Andriole [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount $ 1,312,421    
PEO Actually Paid Compensation Amount $ 764,028    
PEO Name Mike Andriole    
PEO | Mike Sherman [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ 961,623    
PEO | Mike Sherman [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 353,236    
PEO | Mike Sherman [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (634,755)    
PEO | Mike Sherman [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 98,648    
PEO | Mike Sherman [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (342,262)    
PEO | Mike Andriole [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 492,416    
PEO | Mike Andriole [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 246,830    
PEO | Mike Andriole [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (219,881)    
PEO | Mike Andriole [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 34,147    
PEO | Mike Andriole [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (117,073)    
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 244,105    
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 89,668    
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (176,242)    
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 25,041    
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ (95,470)