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Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenues:      
Total revenues $ 324,000 $ 33,824,000 $ 1,979,000
Cost of goods sold 0 447,000 0
Gross Profit 324,000 33,377,000 1,979,000
Operating expenses:      
Research and development 68,788,000 71,631,000 73,817,000
General and administrative 24,601,000 22,132,000 18,672,000
Acquired in-process research and development 0 0 82,890,000
Total operating expenses 93,389,000 93,763,000 175,379,000
Loss from operations (93,065,000) (60,386,000) (173,400,000)
Other income:      
Interest income and other, net 10,970,000 2,919,000 164,000
Gain on sale of business, net 0 229,670,000 0
(Loss) income before income taxes (82,095,000) 172,203,000 (173,236,000)
Income tax expense 0 36,000 0
Net (loss) income (82,095,000) 172,167,000 (173,236,000)
Other comprehensive income (loss):      
Unrealized gain (loss) on debt investments, net 344,000 (316,000) (21,000)
Comprehensive (loss) income $ (81,751,000) $ 171,851,000 $ (173,257,000)
Per share information:      
Net (loss) income, basic (in dollars per share) $ (0.93) $ 1.97 $ (2.04)
Net (loss) income, diluted (in dollars per share) $ (0.93) $ 1.94 $ (2.04)
Weighted-average shares outstanding, basic (in shares) 88,604,026 87,555,110 84,930,255
Weighted-average shares outstanding, diluted (in shares) 88,604,026 88,776,147 84,930,255
Procurement revenue      
Revenues:      
Total revenues $ 0 $ 31,971,000 $ 0
Contract and grant revenue      
Revenues:      
Total revenues 275,000 942,000 1,928,000
Licensing revenue      
Revenues:      
Total revenues 49,000 536,000 51,000
Royalty revenue      
Revenues:      
Total revenues $ 0 $ 375,000 $ 0