X0508 4 2025-08-08 0001116463 ORASURE TECHNOLOGIES INC OSUR 0001942342 McGrath Kenneth J C/O ORASURE TECHNOLOGIES, INC. 220 EAST FIRST STREET BETHLEHEM PA 18015 0 1 0 0 Chief Financial Officer 0 Common Stock 2025-08-08 4 F 0 12524 2.78 D 448463 D Withholding of shares to pay the tax liability associated with vesting of restricted shares. /s/ Michele Anthony, Attorney-In-Fact 2025-08-11