X0407 4 2023-06-28 0001116463 ORASURE TECHNOLOGIES INC OSUR 0001337791 Datin James A 220 EAST FIRST STREET BETHLEHEM PA 18015 1 0 0 0 0 Common Stock 2023-06-28 4 A 0 4004 4.995 A 81566 D Common Stock 2023-06-28 4 F 0 1084 4.995 D 80482 D Grant of restricted shares under the OraSure Technologies, Inc. Stock Award Plan, with immediate vesting on date of grant. Shares issued in lieu of cash fees at Reporting Person's election under the Company's Director Compensation Policy. Withholding of shares to pay the tax liability associated with vesting of restricted shares. /s/ Michele Anthony, Attorney-In-Fact 2023-06-30