X0306 4 2022-05-16 0001116463 ORASURE TECHNOLOGIES INC OSUR 0001593283 Whitaker Anne Clem 220 EAST FIRST STREET BETHLEHEM PA 18015 1 0 0 0 Common Stock 2022-05-16 4 A 0 20000 5.25 A 30563 D Grant of restricted shares under the OraSure Technologies, Inc. Stock Award Plan, cliff vesting on May 15, 2023. Vesting shall cease immediately if the named individual voluntarily ceases to serve as a member of the Board of Directors. /s/ Michele M. Miller, Attorney-in-Fact 2022-05-18