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Income Taxes - Reconciliation of U.S. Federal Statutory Income Tax Rate to Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]      
U.S. Statutory Rate 21.00% 21.00% 21.00%
Change in valuation allowance (42.00%) (54.70%) (33.30%)
State taxes (net of federal benefit) 0.10% 0.40% 0.20%
Federal research and development credit 18.60% 16.50% 8.50%
Stock-based compensation 10.40% 16.10% 10.20%
Inducement premium   5.00% (4.70%)
Unrecognized tax benefits (4.70%) (4.10%) (2.10%)
Other, net (2.80%) (1.00%) (0.10%)
Effective income tax rate 0.70% (0.80%) (0.30%)