X0306 4 2015-03-03 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001114913 LAPALME PIERRE C/O BIOMARIN PHARMACEUTICAL INC. 105 DIGITAL DRIVE NOVATO CA 94949 1 0 0 0 Common Stock 2015-03-03 2015-03-03 4 M 0 10000 11.15 A 40150 D Common Stock 2015-03-03 2015-03-03 4 M 0 10000 17.33 A 50150 D Common Stock 2015-03-03 2015-03-03 4 S 0 20000 106.57 D 30150 D Common Stock 1500 I Shares held by spouse Stock Option (right to buy Common Stock) 11.15 2015-03-03 2015-03-03 4 M 0 10000 0 D 2006-07-27 2016-01-26 Common Stock 10000 0 D Stock Option (right to buy Common Stock) 17.33 2015-03-03 2015-03-03 4 M 0 10000 0 D 2007-12-07 2017-06-06 Common Stock 10000 12500 D The price in column 4 is an average weighted price. The price actually received ranged from $106.20 to 106.895. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range. Original option grant vests 6/48ths on July 27, 2006, and 1/48th on the 27th of each month thereafter. Reflects the number of stock options that remain outstanding from this specific stock option grant following the reported transaction. Original option grant vests 6/48ths on December 7, 2007, and 1/48th on the 7th of each month thereafter. /s/ Laura Randall Woodhead, Attorney-in-Fact 2015-03-05