X0303 4 2011-02-23 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001114913 LAPALME PIERRE C/O BIOMARIN PHARMACEUTICAL INC. 105 DIGITAL DRIVE NOVATO CA 94949 1 0 0 0 Common Stock 2011-02-23 2011-02-23 4 M 0 100 8.47 A 18850 D Common Stock 2011-02-23 2011-02-23 4 S 0 100 26.00 D 18750 D Common Stock 2011-02-24 2011-02-24 4 M 0 15000 5.92 A 33750 D Common Stock 2011-02-24 2011-02-24 4 S 0 15000 24.9397 D 18750 D Common Stock 1500 I Shares held by spouse Stock Option (right to buy) 8.47 2011-02-23 2011-02-23 4 M 0 100 0 D 2004-04-27 2014-01-26 Common Stock 100 142400 D Stock Option (right to buy) 5.92 2011-02-24 2011-02-24 4 M 0 15000 0 D 2005-04-27 2015-01-26 Common Stock 15000 127400 D The price in Column 4 is a weighted average price. The prices actually received range from $24.91 to $25.00. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Original option grant vested 1/4 each on April 27, 2004, July 27, 2004, October 27, 2004, and January 27, 2005. Original option grant vested 1/4 each on April 27, 2005, July 27, 2005, October 27, 2005, and January 27, 2006. Laura Randall Woodhead, Attorney-in-Fact 2011-02-24