144 0001114357 XXXXXXXX LIVE 0001717115 Tempus AI, Inc. 001-42130 600 W. Chicago Ave., Suite 510 Chicago IL 60654 800-976-5448 Eric Lefkofsky Officer Director 10% Stockholder Class A Common J.P. Morgan Securities LLC

390 Madison Avenue - 6th Floor New York NY 10017

332500 25236750 168683769 08/27/2025 Nasdaq Class A Common 02/14/2025 Stock Compensation Issuer N 41401 02/14/2025 Compensation Class A Common 02/19/2025 Stock Compensation Issuer N 103897 02/19/2025 Compensation Class A Common 02/13/2025 Stock Compensation Issuer N 109943 02/13/2025 Compensation Class A Common 02/12/2025 Stock Compensation Issuer N 10759 02/12/2025 Compensation Class A Common 09/14/2017 Direct Investment Issuer N 66500 09/14/2017 Cash N Eric Lefkofsky

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 08/19/2025 17458 1369580.1 Blue Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 06/17/2025 200000 14013807.86 Blue Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 06/18/2025 200000 13882413.24 Blue Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 07/28/2025 133000 8361451.85 Gray Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 06/17/2025 50000 3502784.72 Gray Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 06/18/2025 50000 3477055.81 Gray Media, LLC

Care of Tempus AI, Inc 600 West Chicago Avenue, Suite 510 Chicago IL 60654

Class A Common 07/28/2025 33250 2090362.96 This form relates to sales by Blue Media, LLC (266,000 shares) and Gray Media, LLC (66,500 shares), of which Mr. Lefkofsky is the sole manager. 08/27/2025 03/04/2025 /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Eric Lefkofsky