X0306 4 2016-10-24 0 0001114220 KERYX BIOPHARMACEUTICALS INC KERX 0001640447 Neylan John F. C/O KERYX BIOPHARMACEUTICALS, INC. ONE MARINA PARK DRIVE, 12TH FLOOR BOSTON MA 02210 0 1 0 0 Chief Medical Officer Common Stock 2016-10-24 4 S 0 1211 4.72 D 91556 D Sale of a total of 1,211 shares of common stock was made in order to satisfy Dr. Neylan's income tax withholding obligation upon the vesting of 3,750 shares of restricted stock on October 22, 2016. Dr. Neylan had no discretion with respect to such sale, which was transacted automatically in accordance with the Issuer's corporate policies regarding the vesting of restricted stock. Includes 76,250 shares of restricted stock. /s/ Brian Adams, Attorney-in-Fact 2016-10-25