X0306 4 2015-11-09 0 0001114220 KERYX BIOPHARMACEUTICALS INC KERX 0001564955 Madison Greg C/O KERYX BIOPHARMACEUTICALS, INC. 750 LEXINGTON AVENUE NEW YORK NY 10022 1 1 0 0 President and CEO Common Stock 2015-11-09 4 S 0 1638 5.18 D 115081 D Sale of a total of 1,638 shares of common stock was made in order to satisfy Mr. Madison's income tax withholding obligation upon the vesting of 5,000 shares of restricted stock on November 9, 2015. Mr. Madison had no discretion with respect to such sale, which was transacted automatically in accordance with the Issuer's corporate policies regarding the vesting of restricted stock. Includes 58,875 shares of restricted stock. /s/ Brian Adams 2015-11-11