X0306 4 2015-08-20 0 0001114220 KERYX BIOPHARMACEUTICALS INC KERX 0001564955 Madison Greg C/O KERYX BIOPHARMACEUTICALS, INC. 750 LEXINGTON AVENUE NEW YORK NY 10022 1 1 0 0 President and CEO Common Stock 2015-08-20 4 P 0 9984 5.685 A 116719 D The reporting person's purchase of common stock reported herein was matchable under Section 16(b) of the Securities Exchange Act of 1934, to the extent of 1,683 shares, with the reporting person's sale of 1,683 shares of common stock at a price of $6.07 per share on August 10, 2015. The reporting person has agreed to pay Keryx $648, representing the full amount of the profit realized in connection with the short-swing transaction. The reporting person effected multiple same-way open market purchase transactions on the same day at different prices, ranging from $5.68 to $5.71, through a trade order executed by a broker-dealer. The price reported in Column 4 is a weighted average price. The reporting person has reported on a single line all such transactions that occurred within a one dollar price range. The reporting person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the issuer or a shareholder of the issuer, full information regarding the number of shares purchased at each separate price. Includes 63,875 shares of restricted stock. /s/ Brian Adams 2015-08-24