X0202 4 2004-06-23 0 0001113481 MEDICINES CO /DE MDCO 0001204790 RICHARDS JOHN D THE MEDICINES CO 8 CAMPUS DR PARSIPPANY NJ 07054 0 1 0 0 Vice President Common Stock 2004-06-23 4 M 0 1500 3.08 A 7100 D Common Stock 2004-06-23 4 S 0 400 28.5 D 7100 D Common Stock 2004-06-23 4 S 0 100 28.54 D 7100 D Common Stock 2004-06-23 4 S 0 400 28.49 D 7100 D Common Stock 2004-06-23 4 S 0 600 28.48 D 7100 D Common Stock 2004-06-24 4 M 0 3866 3.08 A 7100 D Common Stock 2004-06-24 4 S 0 3866 30 D 7100 D Common Stock 2004-06-24 4 M 0 634 10.11 A 7100 D Common Stock 2004-06-24 4 S 0 534 30 D 7100 D Common Stock 2004-06-24 4 S 0 100 30.01 D 7100 D Stock Option (right to buy) 3.08 2004-06-23 4 M 0 1500 0 D 2004-06-23 2010-03-23 Common Stock 1500 3866 D Stock Option (right to buy) 3.08 2004-06-24 4 M 0 3866 0 D 2004-06-24 2010-03-23 Common Stock 3866 0 D Stock Option (right to buy) 10.11 2004-06-24 4 M 0 634 0 D 2004-06-24 2011-12-11 Common Stock 634 14366 D The common stock sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 program adopted by Mr. Richards on March 23, 2004. As of 6/23/2004 the original grant (14,600 shares granted 3/23/2000) was vested with respect to 14,600, of the shares covered thereby. After the exercise of the options reported hereby, as of 6/23/2004, the remaining 3,866 of the shares covered by the option were vested but not exercised. As of 6/24/2004 the original grant (14,600 shares granted 3/23/2000) was vested with respect to 14,600, of the shares covered thereby. After the exercise of the options reported hereby, as of 6/24/2004, there are 0 (zero) outstanding options remaining in this grant. As of 6/24/2004 the original grant (15,000 shares granted on 12/11/2001) was vested with respect to 9,375, of the shares covered thereby. After the exercise of the options reported hereby, as of 6/24/2004, 8,741 of the shares covered by the option were vested but not exercised and the remaining 5,625 of the shares covered by the option vest in equal monthly installments ending 12/11/2011. John D. Richards 2004-06-24