Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Income Statement [Abstract]
Net revenues	$ (3,300)	$ 7,868	$ 6,138	$ 36,194
Operating expenses:
Cost of revenues	890	4,287	6,558	26,755
Asset impairment charges	5,073	0	5,073	329,097
Research and development	32,736	33,077	103,396	82,770
Selling, general and administrative	6,826	33,765	56,790	102,581
Total operating expenses	45,525	71,129	171,817	541,203
Loss from operations	(48,825)	(63,261)	(165,679)	(505,009)
Co-promotion and license income	271	769	753	2,283
Loss on short-term investment	(7,953)	0	(41,416)	0
Interest expense	(12,313)	(11,810)	(36,498)	(36,753)
Other income	1,119	448	4,541	1,592
Loss from continuing operations before income taxes	(67,701)	(73,854)	(238,299)	(537,887)
Benefit from income taxes	16,066	66,636	47,375	89,608
Loss from continuing operations	(51,635)	(7,218)	(190,924)	(448,279)
(Loss) income from discontinued operations, net of tax	(3,999)	(22,957)	110,242	(81,834)
Net Loss	$ (55,634)	$ (30,175)	$ (80,682)	$ (530,113)
Basic (loss) earnings per common share:
Loss from continuing operations (USD per share)	$ (0.70)	$ (0.10)	$ (2.60)	$ (6.25)
(Loss) earnings from discontinued operations (USD per share)	(0.05)	(0.32)	1.50	(1.14)
Basic loss per share (USD per share)	(0.75)	(0.42)	(1.10)	(7.39)
Diluted (loss) earnings per common share:
Loss from continuing operations (USD per share)	(0.70)	(0.10)	(2.60)	(6.25)
(Loss) earnings from discontinued operations (USD per share)	(0.05)	(0.32)	1.50	(1.14)
Diluted loss per share (USD per share)	$ (0.75)	$ (0.42)	$ (1.10)	$ (7.39)
Weighted average number of common shares outstanding:
Basic (shares)	73,544	72,286	73,564	71,763
Diluted (shares)	73,544	72,286	73,564	71,763