Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands		6 Months Ended
		Jun. 30, 2018	Jun. 30, 2017
Cash flows from operating activities:
Net loss		$ (25,048)	$ (499,938)
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Depreciation and amortization		1,443	11,727
Asset impairment charges		0	329,097
Amortization of debt discount		13,531	13,822
Unrealized foreign currency transaction losses, net		127	523
Stock compensation expense		9,073	16,200
Gain on sale of business		(168,955)	0
Loss on short-term investments		33,463	0
Deferred tax benefit		0	(22,989)
Reserve for excess or obsolete inventory		(394)	2,147
Changes in contingent purchase price		(258)	(4,116)
Changes in operating assets and liabilities:
Accounts receivable		619	6,708
Inventory, net		2,258	(2,605)
Prepaid expenses and other assets		6,687	4,595
Accounts payable		(4,618)	(12,070)
Accrued expenses		(33,253)	1,530
Other current liabilities		(4,181)	(4,960)
Payments on contingent purchase price		(57)	(12,437)
Other liabilities		4,222	(2,586)
Net cash used in operating activities		(165,341)	(175,352)
Cash flows from investing activities:
Purchases of fixed assets		(7)	(4,448)
Purchases of available for sale securities		0	(131,560)
Proceeds from sale of business		166,383	0
Net cash provided by (used in) investing activities		166,376	(136,008)
Cash flows from financing activities:
Proceeds from issuances of common stock, net		11,913	35,859
Payments on contingent purchase price		(511)	(9,565)
Repayments of convertible senior notes		0	(54,997)
Purchase of shares of non-controlling interest		0	(167)
Net cash provided by financing activities		11,402	(28,870)
Effect of exchange rate changes on cash		(1,374)	818
Increase (decrease) in cash, cash equivalents and restricted cash		11,063	(339,412)
Cash, cash equivalents and restricted cash at beginning of period		156,900	546,867
Cash, cash equivalents and restricted cash at end of period	[1]	167,963	207,455
Supplemental disclosure of cash flow information:
Interest paid		10,534	11,988
Non-cash investing and financing activities
Issuance of common stock upon conversion of convertible notes		0	32,018
Receipt of common stock upon settlement of 2017 Note hedge		0	40,015
Reconciliation of cash, cash equivalents and restricted cash
Total cash, cash equivalents and restricted cash at end of period		$ 156,900	$ 546,867

[1] The following table provides a reconciliation of cash, cash equivalents and restricted cash to amounts reported within the condensed consolidated balance sheet:Reconciliation of cash, cash equivalents and restricted cash Cash and cash equivalents$162,530 202,422Restricted cash5,433 5,033Total cash, cash equivalents and restricted cash at end of period$167,963 $207,455