Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Income Statement [Abstract]
Net revenues	$ 1,667	$ 10,861	$ 9,438	$ 28,326
Operating expenses:
Cost of revenues	2,931	12,490	5,668	22,468
Asset impairment charges	0	329,097	0	329,097
Research and development	30,294	23,249	70,660	49,693
Selling, general and administrative	21,013	28,359	49,964	68,816
Total operating expenses	54,238	393,195	126,292	470,074
Loss from operations	(52,571)	(382,334)	(116,854)	(441,748)
Co-promotion and license income	254	757	482	1,514
Loss on short-term investment	(3,474)	0	(33,463)	0
Interest expense	(12,108)	(12,521)	(24,185)	(24,943)
Other income	1,053	1,033	3,422	1,144
Loss from continuing operations before income taxes	(66,846)	(393,065)	(170,598)	(464,033)
Benefit from income taxes	12,393	23,000	31,309	22,972
Loss from continuing operations	(54,453)	(370,065)	(139,289)	(441,061)
Income (loss) from discontinued operations, net of tax	256	(27,203)	114,241	(58,877)
Net Loss	$ (54,197)	$ (397,268)	$ (25,048)	$ (499,938)
Basic (loss) earnings per common share:
Loss from continuing operations (USD per share)	$ (0.74)	$ (5.15)	$ (1.89)	$ (6.17)
Earnings (loss) from discontinued operations (USD per share)	0.00	(0.38)	1.55	(0.82)
Basic earnings (loss) per share (USD per share)	(0.74)	(5.53)	(0.34)	(6.99)
Diluted (loss) earnings per common share:
Loss from continuing operations (USD per share)	(0.74)	(5.15)	(1.89)	(6.17)
Earnings (loss) from discontinued operations (USD per share)	0.00	(0.38)	1.55	(0.82)
Diluted earnings (loss) per share (USD per share)	$ (0.74)	$ (5.53)	$ (0.34)	$ (6.99)
Weighted average number of common shares outstanding:
Basic (shares)	73,349	71,918	73,574	71,498
Diluted (shares)	73,349	71,918	73,574	71,498