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Restructuring (Details)
$ in Thousands
3 Months Ended 9 Months Ended
Jun. 19, 2017
USD ($)
position
Sep. 30, 2017
USD ($)
Jun. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Restructuring, Settlement and Impairment Provisions [Abstract]            
Impairment charge   $ 0   $ 0 $ 329,097 $ 0
Severance and other exits costs $ 5,800          
Other exit costs $ 3,000          
Restructuring Reserve [Roll Forward]            
Balance         0  
Expenses, Net         5,900  
Cash         (5,100)  
Noncash         (100)  
Balance   $ 700     $ 700  
Ionsys | Not discontinued operations, discontinuation and market withdrawal            
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]            
Number of positions eliminated | position 57          
Percent of workforce eliminated 15.00%          
Restructuring, Settlement and Impairment Provisions [Abstract]            
Impairment, severance and other employee costs     $ 276,900      
Impairment charge     268,100      
Severance and other exits costs     $ 8,800