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Nature of Business - Discontinuation and Market Withdrawal (Details) - Ionsys - Not discontinued operations, discontinuation and market withdrawal
$ in Thousands
9 Months Ended
Sep. 30, 2017
USD ($)
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]  
Cost of product revenue $ 8,458
Asset impairment charges 264,097
Research and development 1,032
Selling, general and administrative 3,331
Total operating expenses 276,918
Income (loss) from operations (276,918)
(Loss) income from continuing operations before income taxes (276,918)
Benefit (provision) for income taxes 0
Net (loss) income from continuing operations $ (276,918)