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Restructuring (Details)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 19, 2017
USD ($)
position
Jun. 30, 2017
USD ($)
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
Jun. 30, 2016
USD ($)
Restructuring, Settlement and Impairment Provisions [Abstract]          
Impairment charge   $ 329,097 $ 0 $ 329,097 $ 0
Severance and other exits costs $ 5,900        
Other exit costs $ 3,000        
Restructuring Reserve [Roll Forward]          
Balance       0  
Expenses, Net       5,900  
Cash       (100)  
Noncash       0  
Balance   $ 5,800   $ 5,800  
Ionsys | Not discontinued operations, discontinuation and market withdrawal          
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]          
Number of positions eliminated | position 57        
Percent of workforce eliminated 15.00%        
Restructuring, Settlement and Impairment Provisions [Abstract]          
Impairment, severance and other employee costs $ 277,000        
Impairment charge 268,100        
Severance and other exits costs $ 8,900