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Fair Value Measurements - Fair Value Inputs, Quantitative Information (Details) - USD ($)
$ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2017
Dec. 31, 2016
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 44,471 $ 82,289
Targanta    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 6,171 $ 5,857
Targanta | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 20.00% 20.00%
Discount rate 11.00% 11.00%
Incline    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price   $ 1,269
Incline | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Discount rate   18.00%
Incline | Minimum | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   5.00%
Rempex | Event-based milestones    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 81,400 $ 95,800
Rempex | Event-based milestones | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 77.00% 78.00%
Rempex | Event-based milestones | Minimum | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 18.00% 18.00%
Discount rate 4.20% 5.20%
Rempex | Event-based milestones | Maximum | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 90.00% 95.00%
Discount rate 7.30% 8.50%
Rempex | Sales-based Milestones    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 23,600 $ 20,300
Rempex | Sales-based Milestones | Risk-adjusted revenue simulation    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 61.00% 56.00%
Rempex | Sales-based Milestones | Minimum | Risk-adjusted revenue simulation    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 13.00% 16.00%
Discount rate 5.50% 6.60%
Rempex | Sales-based Milestones | Maximum | Risk-adjusted revenue simulation    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 72.00% 65.00%
Discount rate 6.70% 8.20%
Annovation    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price   $ 14,063
Annovation | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   34.00%
Annovation | Minimum | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   9.00%
Discount rate   6.00%
Annovation | Maximum | Probability-adjusted discounted cash flow    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   50.00%
Discount rate   10.00%