Collaborative Arrangement, Additional Payments

No definition available.

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- Definition

Collaborative Arrangement, Payment for Milestone Met1

+ References

No definition available.

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- Definition

Operating Leases, Percent

+ References

No definition available.

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- Definition

Recorded Unconditional Purchase Obligation Due in Fifth and Sixth Years

+ References

No definition available.

+ Details

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- Definition

Recorded Unconditional Purchase Obligation Due in Second Through Fourth Year

+ References

No definition available.

+ Details

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- Definition

Area of a real estate property.

+ References

No definition available.

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- Definition

Amount of rent expense incurred for leased assets, including but not limited to, furniture and equipment, that is not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

+ References

No definition available.

+ Details

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- Definition

Term of the lessee's leasing arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

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- Definition

Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 10
-Section 55
-Paragraph 40
-Subparagraph (Note 3)
-URI http://asc.fasb.org/extlink&oid=6584154&loc=d3e38371-112697

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 20
-Section 50
-Paragraph 2
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41502-112717

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- Definition

Amount of the recorded obligation to transfer funds in the future for fixed or minimum amounts or quantities of goods or services at fixed or minimum prices (for example, as in take-or-pay contracts or throughput contracts).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 440
-SubTopic 10
-Section 50
-Paragraph 6
-URI http://asc.fasb.org/extlink&oid=73718637&loc=d3e25383-109308

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- Definition

Amount of the recorded unconditional purchase obligation maturing after the fifth fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date.

+ References

+ Details

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- Definition

Amount of the recorded unconditional purchase obligation maturing in the next fiscal year following the latest fiscal year. Excludes interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date.

+ References

+ Details

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- References

No definition available.

+ Details

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- Definition

Amount of expense related to royalty payments under a contractual arrangement such as payment for mineral and drilling rights and use of technology or intellectual property.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.3)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

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Commitments and Contingencies (Details) $ in Thousands	12 Months Ended
Commitments and Contingencies (Details) $ in Thousands	Dec. 31, 2016 USD ($) ft²	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Oct. 01, 2014 ft²
Future Estimated Contract Obligations
Less Than 1 Year	$ 73,435
1-3 Years	28,752
3-5 Years	15,471
More Than 5 Years	33,853
Total	$ 151,511
Leased area (sqft) \| ft²	173,146
Operating leases, percent	97.40%
Aggregate rent expense under property leases	$ 7,600	$ 7,300	$ 7,600
Targanta [Member]
Future Estimated Contract Obligations
Payment for milestone met	49,400
Additional payments	25,000
Incline [Member]
Future Estimated Contract Obligations
Payment for milestone met	60,000
Additional payments	83,000
Rempex [Member]
Future Estimated Contract Obligations
Payment for milestone met	289,200
Annovation [Member]
Future Estimated Contract Obligations
Payment for milestone met	26,300
Additional payments	6,500
Alnylam [Member]
Future Estimated Contract Obligations
Payment for milestone met	170,000
Other [Member]
Future Estimated Contract Obligations
Payment for milestone met	1,200
Biogen Idec and HRI [Member]
Future Estimated Contract Obligations
Royalties	800	1,800	129,400
Cleviprex [Member]
Future Estimated Contract Obligations
Royalties	$ 600	$ 1,300	$ 800
Building [Member]
Future Estimated Contract Obligations
Leased area (sqft) \| ft²				63,000
Lease term	144 months
Expected total obligation for lease	$ 35,300
Inventory related commitments [Member]
Future Estimated Contract Obligations
Less Than 1 Year	17,945
1-3 Years	0
3-5 Years	0
More Than 5 Years	0
Total	17,945
Inventory related commitments [Member] \| Angiomax [Member]
Future Estimated Contract Obligations
Less Than 1 Year	7,000
Inventory related commitments [Member] \| Orbactiv [Member]
Future Estimated Contract Obligations
Less Than 1 Year	8,900
Research and development [Member]
Future Estimated Contract Obligations
Less Than 1 Year	41,330
1-3 Years	12,175
3-5 Years	523
More Than 5 Years	124
Total	54,152
Operating leases [Member]
Future Estimated Contract Obligations
Less Than 1 Year	7,213
1-3 Years	14,569
3-5 Years	14,811
More Than 5 Years	33,729
Total	70,322
Selling, general and administrative [Member]
Future Estimated Contract Obligations
Less Than 1 Year	6,947
1-3 Years	2,008
3-5 Years	137
More Than 5 Years	0
Total	9,092
Research and development, and selling, general and administrative [Member]
Future Estimated Contract Obligations
Total	$ 29,600