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Fair Value Measurements - Level 3 Inputs (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 82,289 $ 96,957
Targanta [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 5,857 $ 5,857
Targanta [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 20.00% 20.00%
Discount rate 11.00% 11.00%
Incline [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 1,269 $ 28,600
Incline [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 5.00% 67.00%
Discount rate 18.00% 18.00%
Incline [Member] | Minimum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   64.00%
Incline [Member] | Maximum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success   72.00%
Rempex [Member] | Event-based milestones [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 95,800 $ 63,000
Rempex [Member] | Event-based milestones [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 79.00% 56.00%
Rempex [Member] | Event-based milestones [Member] | Minimum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 18.00% 11.00%
Discount rate 5.20% 3.60%
Rempex [Member] | Event-based milestones [Member] | Maximum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 95.00% 95.00%
Discount rate 8.50% 6.00%
Rempex [Member] | Sales-based milestones [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 20,300 $ 10,300
Rempex [Member] | Sales-based milestones [Member] | Adjusted revenue simulation [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 56.00% 30.00%
Rempex [Member] | Sales-based milestones [Member] | Minimum [Member] | Adjusted revenue simulation [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 16.00% 11.00%
Discount rate 6.60% 5.50%
Rempex [Member] | Sales-based milestones [Member] | Maximum [Member] | Adjusted revenue simulation [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 65.00% 63.00%
Discount rate 8.20% 6.70%
Annovation [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Contingent purchase price $ 14,063 $ 16,000
Annovation [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 34.00% 31.00%
Annovation [Member] | Minimum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 9.00% 8.00%
Discount rate 6.00% 4.10%
Annovation [Member] | Maximum [Member] | Adjusted discounted cash flow [Member]    
Fair Value Inputs, Assets, Quantitative Information [Line Items]    
Probability of success 50.00% 50.00%
Discount rate 10.00% 8.20%