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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Feb. 26, 2009
Income Tax Contingency [Line Items]        
Statutory federal income tax rate 35.00% 35.00% 35.00%  
Increase in valuation allowance $ 95,000 $ 55,000    
Valuation allowance 162,892 67,890    
Federal net operating loss carryforwards 614,751      
Unrecognized tax benefits, if recognized, would impact effective tax rate 1,900 $ 1,900 $ 8,000  
Foreign [Member]        
Income Tax Contingency [Line Items]        
Federal net operating loss carryforwards 51,100      
Alternative Minimum Tax Credits [Member]        
Income Tax Contingency [Line Items]        
Tax credit carryforwards $ 4,900      
Targanta [Member]        
Income Tax Contingency [Line Items]        
Percentage of voting interests acquired       100.00%