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Earnings per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Jun. 30, 2012
Amounts attributable to The Medicines Company:                          
Net (loss) income from continuing operations   $ (124,428) $ (86,354) $ 181,823 $ (90,343) $ (68,241) $ (90,617) $ (67,445) $ 4,373 $ (119,302) $ (221,930) $ 319  
Income (loss) from discontinued operations, net of tax   1,574 96 619 (2,105) (137,825) (14,515) 20,853 661 184 (130,826) (32,529)  
Net loss attributable to The Medicines Company   $ (122,854) $ (86,258) $ 182,442 $ (92,448) $ (206,066) $ (105,132) $ (46,592) $ 5,034 $ (119,118) $ (352,756) $ (32,210)  
Weighted average common shares outstanding, basic (shares)                   69,909,000 66,809,000 64,473,000  
Plus: net effect of dilutive stock options, warrants, restricted common shares and shares issuable upon conversion of Notes (shares)                   0 0 2,195,000  
Weighted average common shares outstanding, diluted (shares)                   69,909,000 66,809,000 66,668,000  
Basic (loss) income per common share attributable to The Medicines Company:                          
(Loss) income from continuing operations (usd per share)                   $ (1.71) $ (3.32) $ 0.00  
Income (loss) from discontinued operations (usd per share)                   0.00 (1.96) (0.50)  
Basic loss per share (usd per share)                   (1.71) (5.28) (0.50)  
Diluted (loss) income per common share attributable to The Medicines Company:                          
(Loss) income from continuing operations (usd per share)   $ (1.77) $ (1.23) $ 2.51 $ (1.31) $ (0.99) $ (1.35) $ (1.02) $ 0.07 (1.71) (3.32) 0.00  
Income (loss) from discontinued operations (usd per share)   0.02 0.00 0.01 (0.03) (2.00) (0.22) 0.31 0.01 0.00 (1.96) (0.49)  
Diluted loss per share (usd per share)   $ (1.75) $ (1.23) $ 2.52 $ (1.34) $ (2.99) $ (1.57) $ (0.71) $ 0.08 $ (1.71) $ (5.28) $ (0.49)  
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]                          
Antidilutive shares excluded from computation of earnings per share (in shares)                   3,112,627 3,724,272    
2017 Warrants [Member]                          
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]                          
Shares exercisable upon conversion                         2,000,000
Exercise price of warrants (usd per share)                         $ 34.20
Restricted stock [Member]                          
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]                          
Antidilutive shares excluded from computation of earnings per share (in shares)                       3,915,906  
Convertible Senior Notes Due 2023 [Member] | Senior Notes [Member] | Capped call [Member]                          
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]                          
Strike price, capped calls (usd per share) $ 48.97                        
Cap price (usd per share) $ 64.68                        
Convertible Senior Notes Due 2017 [Member] | Senior Notes [Member]                          
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]                          
Debt, aggregate principal amount repurchased       $ 220,000