Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2016

Commitments and Contingencies Disclosure [Abstract]

Future Estimated Contractual Obligations

Future estimated contractual obligations as of December 31, 2016 are:

Contractual Obligations (1)	Less Than 1 Year		1-3 Years		3-5 Years		More Than 5 Years		Total
	(In thousands)
Inventory related commitments	$	17,945	$	—	$	—	$	—	$	17,945
Research and development	41,330		12,175		523		124		54,152
Operating leases	7,213		14,569		14,811		33,729		70,322
Selling, general and administrative	6,947		2,008		137		—		9,092
Total contractual obligations	$	73,435	$	28,752	$	15,471	$	33,853	$	151,511

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(1) This table does not include any milestone and royalty payments which may become payable to third parties for which the timing and likelihood of such payments are not known, as discussed below. It also does not include the long-term debt obligations. See Note 10 “Convertible Senior Notes” for further details.