Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015
Cash flows from operating activities:
Net (loss) income	$ 3,686	$ (146,674)
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Depreciation and amortization	22,517	24,180
Asset impairment charges	0	29,413
Amortization of debt discount	19,392	17,532
Unrealized foreign currency transaction gains, net	(125)	(576)
Stock compensation expense	24,541	23,973
Gain on sale of businesses	(289,305)	0
Loss on disposal of fixed assets	1	543
Deferred tax benefit	(1,661)	(43,393)
Extinguishment of debt	5,380	0
Gain on sale of investment	0	(19,773)
Gain on remeasurement of equity investment	0	(22,597)
Reserve for excess or obsolete inventory	7,350	40,837
Changes in contingent consideration obligations	13,573	14,423
Changes in operating assets and liabilities:
Accrued interest receivable	(13)	0
Accounts receivable	24,125	115,797
Inventory, net	(14,077)	(57,783)
Prepaid expenses and other current assets	1,920	(7,378)
Accounts payable	(17,265)	(2,113)
Accrued expenses	(49,110)	(21,655)
Deferred revenue	(5,761)	25,161
Payments on contingent purchase price	0	(49,192)
Other liabilities	(6,153)	(6,186)
Net cash used in operating activities	(260,985)	(85,461)
Cash flows from investing activities:
Proceeds from sale of fixed assets	0	250
Proceeds from sale of investment	0	19,773
Purchases of fixed assets	(920)	(2,421)
Acquisition of business, net of cash acquired	0	(28,397)
Payments for intangible assets	(10,000)	(112,617)
Proceeds from sale of businesses	437,875	0
Change in restricted cash	(3,660)	61
Net cash provided by (used in) investing activities	423,295	(123,351)
Cash flows from financing activities:
Proceeds from issuances of common stock, net	27,404	89,718
Milestone payments	(7,921)	(130,058)
Proceeds from the issuance of convertible senior notes	402,500	400,000
Repayments of convertible senior notes	(323,225)	0
Purchase of capped call transactions related to convertible senior notes	(33,931)	0
Proceeds from settlement of bond hedges related to convertible senior notes	100,459	0
Settlement of warrants	(87,874)	0
Debt and equity issuance costs	(11,725)	(12,769)
Net cash provided by financing activities	65,687	346,891
Effect of exchange rate changes on cash	(814)	(12)
Increase in cash and cash equivalents	227,183	138,067
Cash and cash equivalents at beginning of period	373,173	370,741
Cash and cash equivalents at end of period	600,356	508,808
Supplemental disclosure of cash flow information:
Interest paid	11,891	6,946
Taxes paid	$ 27	$ 89