Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015
Cash flows from operating activities:
Net income (loss)	$ 89,957	$ (41,533)
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Depreciation and amortization	14,586	14,929
Asset impairment charges	0	3,613
Amortization of debt discount	12,770	11,436
Unrealized foreign currency transaction gains, net	(264)	(146)
Stock compensation expense	16,551	16,283
Gain on sale of businesses	(289,305)	0
Loss on disposal of fixed assets	0	530
Deferred tax benefit	(1,623)	(18,312)
Excess tax expense from share-based compensation arrangements	0	53
Extinguishment of debt	5,380	0
Gain on sale of investment	0	(19,773)
Gain on remeasurement of equity investment	0	(22,597)
Reserve for excess or obsolete inventory	0	8,437
Change in contingent consideration obligation	1,336	13,676
Changes in operating assets and liabilities:
Accrued interest receivable	(13)	0
Accounts receivable	3,974	102,953
Inventory, net	(10,219)	(54,644)
Prepaid expenses and other current assets	(2,683)	(1,276)
Accounts payable	(9,320)	(2,165)
Accrued expenses	(38,377)	(36,286)
Deferred revenue	(3,450)	(2,399)
Payments on contingent purchase price	0	(48,867)
Other liabilities	(1,629)	(5,918)
Net cash used in operating activities	(212,329)	(82,006)
Cash flows from investing activities:
Proceeds from sale of fixed assets	0	250
Proceeds from sale of investment	0	19,773
Purchases of fixed assets	171	(1,488)
Acquisition of business, net of cash acquired	0	(28,397)
Payments for intangible assets	(10,000)	(97,617)
Proceeds from sale of businesses	437,875	0
Change in restricted cash	(12)	13
Net cash provided by (used in) investing activities	428,034	(107,466)
Cash flows from financing activities:
Proceeds from issuances of common stock, net	16,911	20,785
Milestone payments	(6,522)	(126,783)
Proceeds from the issuance of convertible senior notes	402,500	400,000
Repayments of convertible senior notes	(323,225)	0
Purchase of capped call transactions related to convertible senior notes	(33,931)	0
Proceeds from settlement of bond hedges related to convertible senior notes	100,459	0
Settlement of warrants	(87,874)	0
Debt and equity issuance costs	(11,725)	(12,769)
Excess tax expense from share-based compensation arrangements	0	(53)
Net cash provided by financing activities	56,593	281,180
Effect of exchange rate changes on cash	(1,275)	294
Increase in cash and cash equivalents	271,023	92,002
Cash and cash equivalents at beginning of period	373,173	370,741
Cash and cash equivalents at end of period	644,196	462,743
Supplemental disclosure of cash flow information:
Interest paid	6,891	1,891
Taxes paid	$ 27	$ 61