Acquisitions (Details) - USD ($) $ in Thousands		3 Months Ended		9 Months Ended
	Feb. 02, 2015	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014	Feb. 01, 2015	Dec. 31, 2014
Business Acquisition [Line Items]
Gain on remeasurement of equity investment		$ 0	$ 0	$ 22,741	$ 0
Assets Acquired and Liabilities Assumed
Goodwill		$ 313,165		$ 313,165			$ 286,532
Annovation [Member]
Business Acquisition [Line Items]
Payments to acquire businesses	$ 28,397
Ownership interest						35.80%
Fair value of interest	25,886
Gain on remeasurement of equity investment	22,700
Total cash consideration and fair value of existing equity interest	54,283
Fair value of contingent cash payment	18,000
Total purchase price	72,283
Assets Acquired and Liabilities Assumed
Cash and cash equivalents	1,482
Other current assets	692
IPR&D	65,000
Goodwill	24,530
Total assets	91,704
Accrued expenses	398
Contingent purchase price	18,000
Deferred tax liability	19,023
Total liabilities	37,421
Total cash price paid upon acquisition and fair value of existing equity interest	54,283
Annovation [Member] | Commercial Milestones [Member]
Business Acquisition [Line Items]
Additional Milestone Payment	$ 26,300