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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Cash flows from operating activities:    
Net income (loss) $ 5,006us-gaap_ProfitLoss $ (5,005)us-gaap_ProfitLoss
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 7,561us-gaap_DepreciationDepletionAndAmortization 7,938us-gaap_DepreciationDepletionAndAmortization
Amortization of long term debt financing costs 562us-gaap_AmortizationOfFinancingCosts 320us-gaap_AmortizationOfFinancingCosts
Amortization of debt discount 4,954us-gaap_AmortizationOfDebtDiscountPremium 2,595us-gaap_AmortizationOfDebtDiscountPremium
Unrealized foreign currency transaction (gain) loss, net (151)us-gaap_ForeignCurrencyTransactionGainLossUnrealized (113)us-gaap_ForeignCurrencyTransactionGainLossUnrealized
Non-cash share-based compensation expense 7,618us-gaap_ShareBasedCompensation 7,372us-gaap_ShareBasedCompensation
Undistributed loss on equity method investments 144us-gaap_IncomeLossFromEquityMethodInvestments 0us-gaap_IncomeLossFromEquityMethodInvestments
Loss on disposal of fixed assets 530us-gaap_GainLossOnSaleOfPropertyPlantEquipment 7us-gaap_GainLossOnSaleOfPropertyPlantEquipment
Deferred tax provision (433)us-gaap_DeferredIncomeTaxExpenseBenefit 1,669us-gaap_DeferredIncomeTaxExpenseBenefit
Excess tax benefit from share-based compensation arrangements 282us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities (1,670)us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities
Gain on remeasurement of equity investment (22,741)us-gaap_BusinessCombinationStepAcquisitionEquityInterestInAcquireeRemeasurementGain 0us-gaap_BusinessCombinationStepAcquisitionEquityInterestInAcquireeRemeasurementGain
Adjustment to contingent purchase price 1,417mdco_AdjustmentToContingentPurchasePrice 2,264mdco_AdjustmentToContingentPurchasePrice
Changes in operating assets and liabilities:    
Accrued interest receivable   1us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet
Accounts receivable 56,032us-gaap_IncreaseDecreaseInAccountsReceivable (2,768)us-gaap_IncreaseDecreaseInAccountsReceivable
Inventory (46,006)us-gaap_IncreaseDecreaseInInventories 1,120us-gaap_IncreaseDecreaseInInventories
Prepaid expenses and other current assets 1,214us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets (314)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Accounts payable (6,142)us-gaap_IncreaseDecreaseInAccountsPayable (19,575)us-gaap_IncreaseDecreaseInAccountsPayable
Accrued expenses (44,230)us-gaap_IncreaseDecreaseInAccruedLiabilities 7,740us-gaap_IncreaseDecreaseInAccruedLiabilities
Deferred revenue (933)us-gaap_IncreaseDecreaseInDeferredRevenue (4,087)us-gaap_IncreaseDecreaseInDeferredRevenue
Other liabilities (5,713)us-gaap_IncreaseDecreaseInOtherOperatingLiabilities (2,583)us-gaap_IncreaseDecreaseInOtherOperatingLiabilities
Net cash used in operating activities (41,029)us-gaap_NetCashProvidedByUsedInOperatingActivities (5,089)us-gaap_NetCashProvidedByUsedInOperatingActivities
Cash flows from investing activities:    
Proceeds from sale of fixed assets 250us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment 0us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment
Purchases of fixed assets (632)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (3,393)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Cash used for acquisitions, net (28,397)us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired (63)us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired
Payments for intangible assets (90,617)us-gaap_PaymentsToAcquireIntangibleAssets 0us-gaap_PaymentsToAcquireIntangibleAssets
Decrease in restricted cash 17us-gaap_IncreaseDecreaseInRestrictedCash 83us-gaap_IncreaseDecreaseInRestrictedCash
Net cash used in investing activities (119,379)us-gaap_NetCashProvidedByUsedInInvestingActivities (3,373)us-gaap_NetCashProvidedByUsedInInvestingActivities
Cash flows from financing activities:    
Proceeds from issuances of common stock 11,975us-gaap_ProceedsFromIssuanceOfCommonStock 8,582us-gaap_ProceedsFromIssuanceOfCommonStock
Milestone payments (1,000)mdco_CollaborativeArrangementMilestonePayment 0mdco_CollaborativeArrangementMilestonePayment
Proceeds from issuance of convertible senior notes 400,000us-gaap_ProceedsFromConvertibleDebt 0us-gaap_ProceedsFromConvertibleDebt
Debt issuance costs (12,769)us-gaap_PaymentsOfDebtIssuanceCosts 0us-gaap_PaymentsOfDebtIssuanceCosts
Excess tax benefit from share-based compensation arrangements (282)us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities 1,670us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities
Net cash provided by financing activities 397,924us-gaap_NetCashProvidedByUsedInFinancingActivities 10,252us-gaap_NetCashProvidedByUsedInFinancingActivities
Effect of exchange rate changes on cash (1,184)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents (141)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents
Increase in cash and cash equivalents 236,332us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 1,649us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period 370,741us-gaap_CashAndCashEquivalentsAtCarryingValue 376,727us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period 607,073us-gaap_CashAndCashEquivalentsAtCarryingValue 378,376us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of cash flow information:    
Taxes paid $ 45us-gaap_IncomeTaxesPaid $ 1,180us-gaap_IncomeTaxesPaid