Subsequent Events Annovation (Details) (Subsequent Event [Member], USD $)	0 Months Ended	1 Months Ended
	Feb. 02, 2015	Feb. 28, 2015	Feb. 02, 2015
Annovation [Member]
Subsequent Event [Line Items]
Upfront cash consideration	$ 28,400,000	$ 28,400,000
Milestone payments	26,300,000		26,300,000
The General Hospital Corporation [Member]
Subsequent Event [Line Items]
Milestone payments	$ 6,500,000		$ 6,500,000