Income Taxes (Details) (USD $)	3 Months Ended		12 Months Ended
	Sep. 30, 2012	Dec. 31, 2011	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Income Tax Contingency [Line Items]
Deferred tax assets		$ 9,395,000	$ 13,881,000	$ 9,395,000
Deferred tax assets		78,441,000	46,625,000	78,441,000
Current:
Federal			(2,492,000)	(1,299,000)	(1,380,000)
State			(1,309,000)	(1,677,000)	(1,433,000)
Foreign			(863,000)	(226,000)	0
Total			(4,664,000)	(3,202,000)	(2,813,000)
Deferred:
Federal			(26,388,000)	48,384,000	43,582,000
State			(3,920,000)	5,077,000	(282,000)
Foreign			(66,000)	(225,000)	0
Deferred income tax expense (benefit)			30,374,000	(53,236,000)	(43,300,000)
Benefit (provision) for income taxes			35,038,000	(50,034,000)	(40,487,000)
Components of Income (Loss) Before Income Taxes
Domestic			92,998,000	84,390,000	80,765,000
International			(6,790,000)	(6,547,000)	(16,617,000)
Income before income taxes			86,208,000	77,843,000	64,148,000
Statutory federal income tax rate			35.00%	35.00%	35.00%
Tax Rate Reconciliation [Abstract]
Statutory rate applied to pre-tax income (loss)			30,202,000	27,245,000	22,452,000
State income taxes, net of federal benefit			3,399,000	(2,210,000)	1,115,000
Foreign			2,136,000	(1,263,000)	1,551,000
Tax exempt portion of WilmerHale settlement			0	(4,344,000)	0
Revaluation of Targanta conversion rights			(511,000)	(1,735,000)	602,000
Tax credits			(1,712,000)	(1,000,000)	0
Lobbying costs			171,000	0	1,324,000
Meals and entertainment			386,000	349,000	390,000
Uncertain tax positions			542,000	0	510,000
Other			425,000	(567,000)	181,000
Net operating loss utilization			0	0	(23,438,000)
(Decrease) increase to federal valuation allowances			0	(66,509,000)	(45,174,000)
Income tax (benefit) provision			35,038,000	(50,034,000)	(40,487,000)
Deferred tax assets:
Net operating loss carryforwards		32,437,000	23,501,000	32,437,000
Tax credits		24,072,000	13,581,000	24,072,000
Intangible assets		23,352,000	17,760,000	23,352,000
Stock based compensation		15,692,000	16,994,000	15,692,000
Other		14,841,000	10,386,000	14,841,000
Total deferred tax assets		110,394,000	82,222,000	110,394,000
Valuation allowance		(4,190,000)	(2,425,000)	(4,190,000)
Total deferred tax assets net of valuation allowance		106,204,000	79,797,000	106,204,000
Deferred tax liabilities:
Fixed assets		(979,000)	(1,192,000)	(979,000)
Indefinite lived intangible assets		(17,389,000)	(18,099,000)	(17,389,000)
Total deferred tax liabilities		(18,368,000)	(19,291,000)	(18,368,000)
Net deferred tax assets		87,836,000	60,506,000	87,836,000
Deferred tax asset valuation allowance		4,200,000	2,400,000	4,200,000
Change in valuation allowance against deferred tax assets	(66,500,000)	(66,500,000)
Eliminated deferred tax assets	(500,000)			(22,100,000)
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Gross unrecognized tax benefits, beginning of period			1,891,000	1,891,000
Additions related to current year tax positions			0	0
Additions for prior year tax positions			542,000	0
Reductions for prior year tax positions			0	0
Settlements			0	0
Gross unrecognized tax benefits, ending of period		1,891,000	2,433,000	1,891,000	1,891,000
Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			8,529,000
Federal Net Operating Loss [Member]
Deferred tax liabilities:
Tax carryforwards			60,217,000
Alternative Minimum Tax Credit [Member]
Deferred tax liabilities:
Additional tax carryforwards			4,900,000
Foreign Net Operating Losses [Member]
Deferred tax liabilities:
Tax carryforwards			15,100,000
Year of Expiration 2018 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			0
Year of Expiration 2025 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			224,000
Year of Expiration 2026 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			1,971,000
Year of Expiration 2026 [Member] | Federal Net Operating Loss [Member]
Deferred tax liabilities:
Tax carryforwards			0
Year of Expiration 2027 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			1,028,000
Year of Expiration 2027 [Member] | Federal Net Operating Loss [Member]
Deferred tax liabilities:
Tax carryforwards			16,507,000
Year of Expiration 2028 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			1,186,000
Year of Expiration 2028 [Member] | Federal Net Operating Loss [Member]
Deferred tax liabilities:
Tax carryforwards			38,955,000
Year of Expiration 2029 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			899,000
Year of Expiration 2029 [Member] | Federal Net Operating Loss [Member]
Deferred tax liabilities:
Tax carryforwards			4,755,000
Year of Expiration 2030 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			1,051,000
Year of Expiration 2031 [Member] | Federal Research and Development Tax Credit [Member]
Deferred tax liabilities:
Tax carryforwards			$ 2,170,000