X0305 4 2012-05-16 0001113148 INFINITY PHARMACEUTICALS, INC. INFI 0001239241 EVNIN ANTHONY B C/O VENROCK 530 FIFTH AVENUE, 22ND FLOOR NEW YORK NY 10036 1 0 0 0 Stock Option (right to buy) 12.94 2012-05-16 4 A 0 6000 0 A 2022-05-16 Common Stock 6000 6000 D Stock Option (right to buy) 12.94 2012-05-16 4 A 0 10000 0 A 2022-05-16 Common Stock 10000 10000 D The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as a director of the issuer. The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as Lead Outside Director of the issuer. /s/ Anthony B. Evnin 2012-05-17