X0306 4 2018-01-02 0 0001113148 INFINITY PHARMACEUTICALS, INC. INFI 0001375124 Perkins Adelene Q C/O INFINITY PHARMACEUTICALS, INC. 784 MEMORIAL DRIVE CAMBRIDGE MA 02139 1 1 0 0 Chief Executive Officer Common Stock 2018-01-02 4 A 0 69924 0.00 A 612252 D Common Stock 12391.26 I 401(k) Stock Option (right to buy) 2.23 2018-01-02 4 A 0 180000 0.00 A 2028-01-02 Common Stock 180000 180000 D Represents the reporting person's 2017 contingent compensation award paid in shares of common stock in lieu of cash at the election of the Compensation Committee of the issuer's Board of Directors. Includes 7,308 shares of common stock acquired by Ms. Perkins on December 15, 2017 through participation in the issuer's Employee Stock Purchase Plan. The option vests over a period of two years in equal annual installments on the first and second anniversary of the date of grant. /s/ Adelene Q. Perkins 2018-01-04