X0306 4 2017-05-25 0 0001113148 INFINITY PHARMACEUTICALS, INC. INFI 0001229815 VENUTI MICHAEL C C/O INFINITY PHARMACEUTICALS, INC. 784 MEMORIAL DRIVE CAMBRIDGE MA 02139 1 0 0 0 Stock Option (right to buy) 1.74 2017-05-25 4 A 0 20000 0.00 A 2027-05-25 Common Stock 20000 20000 D Stock Option (right to buy) 1.74 2017-05-25 4 A 0 4000 0.00 A 2027-05-25 Common Stock 4000 4000 D The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as a director of the issuer. The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as Chair of the Research and Development Committee of the issuer's Board of Directors. /s/ Michael C. Venuti 2017-05-25