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    <schemaVersion>X0707</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

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        <cik>0001111485</cik>
        <entityName>RxSight, Inc.</entityName>
        <issuerAddress>
            <street1>100 COLUMBIA STREET</street1>
            <street2>SUITE 120</street2>
            <city>ALISO VIEJO</city>
            <stateOrCountry>CA</stateOrCountry>
            <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
            <zipCode>92656</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>949-521-7822</issuerPhoneNumber>
        <jurisdictionOfInc>CALIFORNIA</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>CALHOUN VISION INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

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            <relatedPersonName>
                <firstName>Ron</firstName>
                <lastName>Kurtz</lastName>
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            <relatedPersonAddress>
                <street1>c/o RxSight, Inc.</street1>
                <street2>100 Columbia, Suite 120</street2>
                <city>Aliso Viejo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92656</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Shelley</firstName>
                <lastName>Thunen</lastName>
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            <relatedPersonAddress>
                <street1>c/o RxSight, Inc.</street1>
                <street2>100 Columbia, Suite 120</street2>
                <city>Aliso Viejo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92656</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Juliet</firstName>
                <lastName>Bakker</lastName>
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                <street1>c/o RxSight, Inc.</street1>
                <street2>100 Columbia, Suite 120</street2>
                <city>Aliso Viejo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92656</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Chris</firstName>
                <lastName>Cox</lastName>
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                <city>Aliso Viejo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92656</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Bruce</firstName>
                <lastName>Robertson</lastName>
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                <street1>c/o RxSight, Inc.</street1>
                <street2>100 Columbia, Suite 120</street2>
                <city>Aliso Viejo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92656</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Dan</firstName>
                <lastName>Schwartz</lastName>
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                <street2>100 Columbia, Suite 120</street2>
                <city>Aliso Viejo</city>
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                <zipCode>92656</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Werner</firstName>
                <lastName>Wolfen</lastName>
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                <zipCode>92656</zipCode>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <lastName>Link</lastName>
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            <relatedPersonAddress>
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                <zipCode>92656</zipCode>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>J.</firstName>
                <middleName>Andy</middleName>
                <lastName>Corley</lastName>
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            <relatedPersonAddress>
                <street1>c/o RxSight, Inc.</street1>
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                <zipCode>92656</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06b</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001111485-17-000005</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2017-02-24</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>77499999</totalOfferingAmount>
            <totalAmountSold>49975202</totalAmountSold>
            <totalRemaining>27524797</totalRemaining>
            <clarificationOfResponse>$46,746,748.80 new cash; $3,228,453.60 upon exercise of warrants</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>62</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>RxSight, Inc.</issuerName>
                <signatureName>/s/ Ron Kurtz</signatureName>
                <nameOfSigner>Ron Kurtz</nameOfSigner>
                <signatureTitle>President &amp; CEO</signatureTitle>
                <signatureDate>2017-04-03</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
