Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions	9 Months Ended
	Oct. 02, 2022	Oct. 03, 2021
Cash flows from operating activities:
Net (loss) income	$ (4,265)	$ 650
Adjustments to reconcile net (loss) income to net cash provided by operating activities:
Depreciation expense	158	128
Amortization of intangible assets	130	34
Share-based compensation expense	266	656
Accretion of debt discount on convertible senior notes	0	26
Deferred income taxes	(40)	(81)
Goodwill impairment	3,914	0
Gain on previously held investment in GRAIL	0	(900)
Net losses (gains) on strategic investments	79	(46)
Loss (gain) on Helix contingent value right	8	(30)
Gain on derivative assets related to terminated acquisition	0	(26)
Change in fair value of contingent consideration liabilities	(230)	(7)
Other	7	26
Changes in operating assets and liabilities:
Accounts receivable	13	(125)
Inventory	(127)	(27)
Prepaid expenses and other current assets	10	(34)
Operating lease right-of-use assets and liabilities, net	(10)	(9)
Other assets	17	(35)
Accounts payable	(51)	(28)
Accrued liabilities	388	81
Other long-term liabilities	(22)	10
Net cash provided by operating activities	245	263
Cash flows from investing activities:
Maturities of available-for-sale securities	0	331
Purchases of available-for-sale securities	0	(77)
Sales of available-for-sale securities	0	1,031
Cash received for derivative assets related to terminated acquisition	0	52
Purchases of property and equipment	(198)	(138)
Purchases of strategic investments	(26)	(44)
Sales of strategic investments	0	220
Net cash paid for acquisitions	(85)	(2,444)
Cash paid for intangible asset	(180)	0
Net cash used in investing activities	(489)	(1,069)
Cash flows from financing activities:
Net proceeds from issuance of debt	0	988
Payments on convertible senior notes	0	(517)
Taxes paid related to net share settlement of equity awards	(19)	(452)
Proceeds from issuance of common stock	63	59
Net cash provided by financing activities	44	78
Effect of exchange rate changes on cash and cash equivalents	(32)	(2)
Net decrease in cash and cash equivalents	(232)	(730)
Cash and cash equivalents at beginning of period	1,232	1,810
Cash and cash equivalents at end of period	$ 1,000	$ 1,080