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Supplemental Balance Sheet Details - Intangible Assets and Goodwill Narrative (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Oct. 02, 2022
Jul. 03, 2022
Oct. 03, 2021
Oct. 02, 2022
Oct. 03, 2021
Jan. 02, 2022
Indefinite-lived Intangible Assets [Line Items]            
Measurement period adjustment       $ (6)    
Goodwill impairment $ 3,914   $ 0 3,914 $ 0  
Goodwill 3,238     3,238   $ 7,113
GRAIL            
Indefinite-lived Intangible Assets [Line Items]            
Measurement period adjustment (6)          
Deferred tax assets $ 6          
Fair value of discount rate (as a percent) 22.00% 16.00%        
Amount exceeding carrying value   $ 700        
Goodwill impairment $ 3,914 0        
Goodwill 2,178     2,178    
Core Illumina            
Indefinite-lived Intangible Assets [Line Items]            
Fair value in excess of carrying amount (more than) 30,000     $ 30,000    
Developed technology            
Indefinite-lived Intangible Assets [Line Items]            
Finite-lived intangible assets acquired   $ 23        
Useful life (in years)   7 years        
Database            
Indefinite-lived Intangible Assets [Line Items]            
Finite-lived intangible assets acquired   $ 12        
Useful life (in years)   7 years        
License | Complete Genomics            
Indefinite-lived Intangible Assets [Line Items]            
Loss contingency, license granted $ 180          
Amortization period (in years) 6 years 6 months