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Stockholders’ Equity - Summary of Share-based Compensation Expense for all Stock Awards (Details)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Feb. 28, 2021
USD ($)
employee
Oct. 02, 2022
USD ($)
Oct. 03, 2021
USD ($)
Oct. 02, 2022
USD ($)
Oct. 03, 2021
USD ($)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense before taxes   $ 83 $ 697 $ 266 $ 844
Related income tax benefits   (18) (29) (60) (57)
Share-based compensation expense, net of taxes   65 668 206 787
Replacement Awards | GRAIL Inc          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     615    
Performance Stock Units (PSU)          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share based compensation vesting performance period (in years) 3 years        
Performance Shares, Granted In 2019          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of employees effected by modification | employee 52        
Incremental share-based compensation cost $ 41        
Performance Shares, Granted In 2020          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of employees effected by modification | employee 72        
Incremental share-based compensation cost $ 65        
Cost of product revenue          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense before taxes   7 7 20 22
Cost of service and other revenue          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense before taxes   2 1 4 3
Research and development          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense before taxes   37 193 112 243
Research and development | Replacement Awards | GRAIL Inc          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     167    
Selling, general and administrative          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense before taxes   $ 37 496 $ 130 $ 576
Selling, general and administrative | Replacement Awards | GRAIL Inc          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     $ 448