Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions	9 Months Ended
	Sep. 27, 2020	Sep. 29, 2019
Cash flows from operating activities:
Consolidated net income	$ 399	$ 751
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation expense	114	113
Amortization of intangible assets	23	30
Share-based compensation expense	116	145
Accretion of debt discount	29	36
Deferred income taxes	50	(13)
Unrealized gains on marketable equity securities	(128)	(57)
Payment of accreted debt discount	0	(84)
Gains on deconsolidation		(54)
Loss on derivative assets related to terminated acquisition	116
Other	(14)	(10)
Changes in operating assets and liabilities:
Accounts receivable	108	(29)
Inventory	(56)	(33)
Prepaid expenses and other current assets	(15)	(14)
Operating lease right-of-use assets and liabilities, net	(9)	(3)
Other assets	(25)	(29)
Accounts payable	(2)	(46)
Accrued liabilities	(68)	(81)
Other long-term liabilities	36	(14)
Net cash provided by operating activities	674	608
Cash flows from investing activities:
Maturities of available-for-sale securities	327	1,262
Purchases of available-for-sale securities	(757)	(760)
Sales of available-for-sale securities	379	528
Proceeds from the deconsolidation of GRAIL		15
Cash paid for derivative assets related to terminated acquisition	(132)
Purchases of property and equipment	(127)	(152)
Deconsolidation of Helix cash	0	(29)
Net purchases of strategic investments	(112)	(15)
Net cash paid for acquisitions	(98)	0
Net cash (used in) provided by investing activities	(520)	849
Cash flows from financing activities:
Payments on financing obligations		(550)
Common stock repurchases	(455)	(261)
Taxes paid related to net share settlement of equity awards	(41)	(30)
Proceeds from issuance of common stock	61	59
Net cash used in financing activities	(435)	(782)
Effect of exchange rate changes on cash and cash equivalents		(4)
Net (decrease) increase in cash and cash equivalents	(281)	671
Cash and cash equivalents at beginning of period	2,042	1,144
Cash and cash equivalents at end of period	$ 1,761	$ 1,815