10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

þ Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

For the Quarterly Period Ended October 1, 2017

¨ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

For the transition period from             to            

Commission File Number 001-35406

Illumina, Inc.

(Exact name of registrant as specified in its charter)

Delaware	33-0804655
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)
5200 Illumina Way, San Diego, CA	92122
(Address of principal executive offices)	(Zip Code)

(858) 202-4500

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes   þ    No   ¨

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).    Yes   þ    No  ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer	þ		Accelerated filer	¨
Non-accelerated filer	¨	(Do not check if a smaller reporting company)	Smaller reporting company	¨
			Emerging growth company	¨

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13a of the Exchange Act. o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).     Yes  ¨    No   þ

As of October 20, 2017, there were 146 million shares of the registrant’s common stock outstanding.

ILLUMINA, INC.

INDEX

	Page
PART I. FINANCIAL INFORMATION
Item 1. Financial Statements	3
Condensed Consolidated Balance Sheets	3
Condensed Consolidated Statements of Income	4
Condensed Consolidated Statements of Comprehensive Income	5
Condensed Consolidated Statement of Stockholders’ Equity	6
Condensed Consolidated Statements of Cash Flows	7
Notes to Condensed Consolidated Financial Statements	8
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations	21
Item 3. Quantitative and Qualitative Disclosures About Market Risk	29
Item 4. Controls and Procedures	29
PART II. OTHER INFORMATION
Item 1. Legal Proceedings	30
Item 1A. Risk Factors	30
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds	30
Item 3. Defaults Upon Senior Securities	30
Item 4. Mine Safety Disclosures	31
Item 5. Other Information	31
Item 6. Exhibits	31
SIGNATURES	32

2

PART I. FINANCIAL INFORMATION

Item 1. Financial Statements.

ILLUMINA, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS

(In millions)

	October 1, 2017			January 1, 2017
	(Unaudited)
ASSETS
Current assets:
Cash and cash equivalents	$	1,354		$	735
Short-term investments	687			824
Accounts receivable, net	383			381
Inventory	327			300
Prepaid expenses and other current assets	54			78
Total current assets	2,805			2,318
Property and equipment, net	862			713
Goodwill	771			776
Intangible assets, net	185			243
Deferred tax assets	117			123
Other assets	306			108
Total assets	$	5,046		$	4,281
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable	$	158		$	138
Accrued liabilities	381			342
Build-to-suit lease liability	124			223
Long-term debt, current portion	2			2
Total current liabilities	665			705
Long-term debt	1,180			1,056
Other long-term liabilities	222			206
Redeemable noncontrolling interests	124			44
Stockholders’ equity:
Common stock	2			2
Additional paid-in capital	2,891			2,733
Accumulated other comprehensive loss	—			(1		)
Retained earnings	2,188			1,485
Treasury stock, at cost	(2,226		)	(2,022		)
Total Illumina stockholders’ equity	2,855			2,197
Noncontrolling interests	—			73
Total stockholders’ equity	2,855			2,270
Total liabilities and stockholders’ equity	$	5,046		$	4,281

See accompanying notes to the condensed consolidated financial statements.

3

ILLUMINA, INC.

CONDENSED CONSOLIDATED STATEMENTS OF INCOME

(Unaudited)

(In millions, except per share amounts)

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Revenue:
Product revenue	$	596		$	514		$	1,631		$	1,506
Service and other revenue	118			93			344			273
Total revenue	714			607			1,975			1,779
Cost of revenue:
Cost of product revenue	173			132			508			383
Cost of service and other revenue	50			38			153			117
Amortization of acquired intangible assets	9			11			30			32
Total cost of revenue	232			181			691			532
Gross profit	482			426			1,284			1,247
Operating expense:
Research and development	134			126			409			374
Selling, general and administrative	167			139			499			438
Legal contingencies	—			—			—			(9		)
Total operating expense	301			265			908			803
Income from operations	181			161			376			444
Other income (expense):
Interest income	4			2			13			7
Interest expense	(10		)	(9		)	(26		)	(25		)
Other income, net	—			—			457			1
Total other (expense) income, net	(6		)	(7		)	444			(17		)
Income before income taxes	175			154			820			427
Provision for income taxes	23			37			199			106
Consolidated net income	152			117			621			321
Add: Net loss attributable to noncontrolling interests	11			12			37			18
Net income attributable to Illumina stockholders	$	163		$	129		$	658		$	339
Net income attributable to Illumina stockholders for earnings per share	$	163		$	129		$	657		$	336
Earnings per share attributable to Illumina stockholders:
Basic	$	1.12		$	0.88		$	4.49		$	2.29
Diluted	$	1.11		$	0.87		$	4.45		$	2.27
Shares used in computing earnings per common share:
Basic	146			147			146			147
Diluted	148			148			148			148

See accompanying notes to the condensed consolidated financial statements.

4

ILLUMINA, INC.

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(Unaudited)

(In millions)

	Three Months Ended					Nine Months Ended
	October 1, 2017		October 2, 2016			October 1, 2017		October 2, 2016
Consolidated net income	$	152	$	117		$	621	$	321
Unrealized gain (loss) on available-for-sale securities, net of deferred tax	1		(1		)	1		1
Total consolidated comprehensive income	153		116			622		322
Add: Comprehensive loss attributable to noncontrolling interests	11		12			37		18
Comprehensive income attributable to Illumina stockholders	$	164	$	128		$	659	$	340

See accompanying notes to the condensed consolidated financial statements.

5

ILLUMINA, INC.

CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS’ EQUITY

(Unaudited)

(In millions)

	Illumina Stockholders
			Additional			Accumulated Other											Total
	Common		Paid-In			Comprehensive			Retained		Treasury			Noncontrolling			Stockholders’
	Stock		Capital			(Loss) Income			Earnings		Stock			Interests			Equity
Balance as of January 1, 2017	$	2	$	2,733		$	(1	)	$	1,485	$	(2,022	)	$	73		$	2,270
Net income (loss)	—		—			—			658		—			(7		)	651
Unrealized gain on available-for-sale securities, net of deferred tax	—		—			1			—		—			—			1
Issuance of common stock, net of repurchases	—		63			—			—		(204		)	—			(141		)
Share-based compensation	—		123			—			—		—			—			123
Adjustment to the carrying value of redeemable noncontrolling interests	—		(30		)	—			—		—			—			(30		)
Vesting of redeemable equity awards	—		(12		)	—			—		—			—			(12		)
Cumulative-effect adjustment from adoption of ASU 2016-09	—		3			—			45		—			—			48
Deconsolidation of GRAIL	—		11			—			—		—			(66		)	(55		)
Balance as of October 1, 2017	$	2	$	2,891		$	—		$	2,188	$	(2,226	)	$	—		$	2,855

See accompanying notes to condensed consolidated financial statements.

6

ILLUMINA, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(Unaudited)

(In millions)

	Nine Months Ended
	October 1, 2017			October 2, 2016
Cash flows from operating activities:
Consolidated net income	$	621		$	321
Adjustments to reconcile net income to net cash provided by operating activities:
Gain on deconsolidation of GRAIL	(453		)	—
Depreciation expense	81			65
Amortization of intangible assets	36			38
Share-based compensation expense	123			102
Accretion of debt discount	23			22
Deferred income taxes	53			58
Impairment of intangible assets	23			—
Other	(2		)	5
Changes in operating assets and liabilities:
Accounts receivable	1			5
Inventory	(27		)	(42		)
Prepaid expenses and other current assets	14			3
Other assets	(3		)	(6		)
Accounts payable	12			(7		)
Accrued liabilities	56			(57		)
Other long-term liabilities	23			10
Net cash provided by operating activities	581			517
Cash flows from investing activities:
Purchases of available-for-sale securities	(359		)	(679		)
Sales of available-for-sale securities	314			406
Maturities of available-for-sale securities	181			148
Net cash paid for acquisitions	—			(18		)
Proceeds from sale of GRAIL securities	278			—
Deconsolidation of GRAIL cash	(52		)	—
Net purchases of strategic investments	(25		)	(9		)
Purchases of property and equipment	(234		)	(178		)
Cash paid for intangible assets	(2		)	(11		)
Net cash provided by (used in) investing activities	101			(341		)
Cash flows from financing activities:
Payments on financing obligations	(7		)	(71		)
Payments on acquisition related contingent consideration liability	(3		)	(29		)
Proceeds from issuance of debt	5			5
Common stock repurchases	(176		)	(113		)
Taxes paid related to net share settlement of equity awards	(28		)	(76		)
Proceeds from issuance of common stock	63			47
Proceeds from early exercise of equity awards from a subsidiary	—			6
Contributions from noncontrolling interest owners	79			80
Net cash used in financing activities	(67		)	(151		)
Effect of exchange rate changes on cash and cash equivalents	4			1
Net increase in cash and cash equivalents	619			26
Cash and cash equivalents at beginning of period	735			769
Cash and cash equivalents at end of period	$	1,354		$	795

See accompanying notes to the condensed consolidated financial statements.

7

Illumina, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

Unless the context requires otherwise, references in this report to “Illumina,” “we,” “us,” the “Company,” and “our” refer to Illumina, Inc. and its consolidated subsidiaries.

1. Basis of Presentation and Summary of Significant Accounting Policies

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (GAAP) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. Interim financial results are not necessarily indicative of results anticipated for the full year. These unaudited condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and footnotes included in the Company’s Annual Report on Form 10-K for the fiscal year ended January 1, 2017, from which the balance sheet information herein was derived. The preparation of financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expense, and related disclosure of contingent assets and liabilities. Actual results could differ from those estimates.

The unaudited condensed consolidated financial statements include the accounts of the Company, its wholly-owned subsidiaries, majority-owned or controlled companies, and variable interest entities (VIEs) for which the Company is the primary beneficiary. All intercompany transactions and balances have been eliminated in consolidation. Effective February 28, 2017, Illumina deconsolidated GRAIL, Inc.’s financial statements. In management’s opinion, the accompanying financial statements reflect all adjustments, consisting of normal recurring adjustments, considered necessary for a fair presentation of the results for the interim periods presented.

The Company evaluates its ownership, contractual, and other interests in entities that are not wholly-owned by the Company to determine if these entities are VIEs, and, if so, whether the Company is the primary beneficiary of the VIE. In determining whether the Company is the primary beneficiary of a VIE and is therefore required to consolidate the VIE, the Company applies a qualitative approach that determines whether it has both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may result in the consolidation or deconsolidation, as the case may be, of such VIE. The Company has not provided financial or other support during the periods presented to its VIEs that it was not previously contractually required to provide.

The equity method is used to account for investments in which the Company has the ability to exercise significant influence, but not control, over the investee. Such investments are recorded within other assets, and the share of net income or losses of equity investments is recognized on a one quarter lag in other income, net.

Redeemable Noncontrolling Interests

Noncontrolling interests represent the portion of equity (net assets) in a consolidated entity that is not wholly-owned by the Company that is not attributable, directly or indirectly, to the Company. Noncontrolling interests with embedded contingent redemption features, such as put rights, that are not solely within the Company’s control are considered redeemable noncontrolling interests. Redeemable noncontrolling interests are presented outside of stockholders’ equity on the condensed consolidated balance sheets.

Fiscal Year

The Company’s fiscal year consists of 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. The three and nine months ended October 1, 2017 and October 2, 2016 were both 13 and 39 weeks, respectively.

8

Reclassifications

Certain prior period amounts have been reclassified to conform to the current period presentation.

Significant Accounting Policies

During the three and nine months ended October 1, 2017, there have been no changes to the Company’s significant accounting policies as described in the Annual Report on Form 10-K for the fiscal year ended January 1, 2017.

Recently Adopted Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board issued Accounting Standard Update (ASU) 2016-09, Compensation - Stock Compensation (Topic 718), which aims to simplify the accounting for share-based payment transactions, including accounting for income taxes, classification on the statement of cash flows, accounting for forfeitures, and classification of awards as either liabilities or equity. This ASU was effective for the Company beginning in the first quarter of 2017.

Under the ASU, excess tax benefits from share-based payment arrangements are classified as discrete items within the provision for income taxes, rather than recognizing excess tax benefits in additional paid-in capital. Upon adoption in Q1 2017, the Company recorded $45 million, net, to retained earnings, primarily related to unrealized tax benefits associated with share-based compensation. During the three and nine months ended October 1, 2017, excess tax benefits of $12 million and $31 million, respectively, were reflected as a component of the provision for income taxes.

In addition, under the ASU, excess income tax benefits from share-based compensation arrangements are classified as cash flow from operations, rather than cash flow from financing activities. The Company has elected to apply the cash flow classification guidance retrospectively and reclassified $110 million from financing activity to operating activity for the nine months ended October 2, 2016.

Recently Issued Accounting Pronouncements

In May 2014, the Financial Accounting Standards Board issued Accounting Standards Update (ASU) 2014-09, Revenue from Contracts with Customers (Topic 606). The new standard is based on the principle that revenue should be recognized in an amount that reflects the consideration to which the entity expects to be entitled in exchange for the transfer of promised goods or services. Since its initial release, the FASB has issued several amendments to the standard, which include clarification of accounting guidance related to identification of performance obligations, intellectual property licenses, and principal vs. agent considerations.

ASU 2014-09 and all subsequent amendments (collectively, the “new standards”) will be effective for the Company beginning in the first quarter of 2018 and may be applied using either the full retrospective method, in which case the standard would be applied to each prior reporting period presented, or the modified retrospective method, in which case the cumulative effect of applying the standard would be recognized at the date of initial application.

The Company continues to work through steps in the implementation project plan, which include: finalizing new disclosures required by the new standards and implementing changes to business processes and reporting in support of the adoption of the new standards. The Company will adopt the new standards using the modified retrospective method with an adjustment to beginning retained earnings for the cumulative effect of the change, which is not expected to be material.

9

In January 2016, the Financial Accounting Standards Board issued ASU 2016-01, Financial Instruments - Overall (Subtopic 825-10), which requires equity investments (other than those accounted for under the equity method or those that result in consolidation) to be measured at fair value, with changes in fair value recognized in net income. ASU 2016-01 will be effective for the Company beginning in the first quarter of 2018. The Company anticipates that the adoption of ASU 2016-01 may increase the volatility of other income and expense, net, as a result of the remeasurement of the Company’s cost-method investments.

In February 2016, the Financial Accounting Standards Board issued ASU 2016-02, Leases (Topic 842). The new standard requires lessees to recognize most leases on their balance sheets as lease liabilities with corresponding right-of-use assets and eliminates certain real estate-specific provisions. ASU 2016-02 will be effective for the Company beginning in the first quarter of 2019. ASU 2016-02 will be adopted on a modified retrospective transition basis for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The Company is currently evaluating the impact of ASU 2016-02 on its consolidated financial statements.

In June 2016, the FASB issued ASU 2016-13, Financial Instruments - Credit Losses: Measurement of Credit Losses on Financial Instruments, which amends the impairment model by requiring entities to use a forward-looking approach based on expected losses to estimate credit losses on certain types of financial instruments, including trade receivables and available for sale debt securities. The ASU is effective for the Company beginning in the first quarter of 2020, with early adoption permitted.  The Company is currently evaluating the impact of ASU 2016-13 on its consolidated financial statements.

Earnings per Share

Basic earnings per share attributable to Illumina stockholders is computed based on the weighted average number of common shares outstanding during the period. Diluted earnings per share attributable to Illumina stockholders is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. Per-share earnings of our VIEs are included in the Company’s consolidated basic and diluted earnings per share computations based on the Company’s share of the VIEs’ securities.

Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. Convertible senior notes have a dilutive impact when the average market price of the Company’s common stock exceeds the applicable conversion price of the respective notes. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares. In loss periods, basic net loss per share and diluted net loss per share are identical because the otherwise dilutive potential common shares become anti-dilutive and are therefore excluded.

The following table presents the calculation of weighted average shares used to calculate basic and diluted earnings per share (in millions):

	Three Months Ended		Nine Months Ended
	October 1, 2017	October 2, 2016	October 1, 2017	October 2, 2016
Weighted average shares outstanding	146	147	146	147
Effect of potentially dilutive common shares from:
Equity awards	2	1	2	1
Weighted average shares used in calculating diluted earnings per share	148	148	148	148
Potentially dilutive shares excluded from calculation due to anti-dilutive effect	—	—	—	1

10

2. Balance Sheet Account Details

Short-Term Investments

The following is a summary of short-term investments (in millions):

	October 1, 2017							January 1, 2017
	Amortized Cost		Gross Unrealized Losses			Estimated Fair Value		Amortized Cost		Gross Unrealized Losses			Estimated Fair Value
Available-for-sale securities:
Debt securities in government sponsored entities	$	74	$	—		$	74	$	34	$	—		$	34
Corporate debt securities	343		(1		)	342		478		(2		)	476
U.S. Treasury securities	272		(1		)	271		316		(2		)	314
Total available-for-sale securities	$	689	$	(2	)	$	687	$	828	$	(4	)	$	824

Realized gains and losses are determined based on the specific identification method and are reported in interest income.

Contractual maturities of available-for-sale debt securities as of October 1, 2017 were as follows (in millions):

	Estimated Fair Value
Due within one year	$	421
After one but within five years	266
Total	$	687

The Company has the ability, if necessary, to liquidate any of its cash equivalents and short-term investments in order to meet its liquidity needs in the next 12 months. Accordingly, those investments with contractual maturities greater than one year from the date of purchase nonetheless are classified as short-term on the accompanying condensed consolidated balance sheets.

Strategic Investments

As of October 1, 2017 and January 1, 2017, the aggregate carrying amounts of the Company’s cost-method investments in non-publicly traded companies included in other assets were $250 million and $57 million, respectively. Revenue recognized from transactions with such companies was $38 million and $96 million, respectively, for the three and nine months ended October 1, 2017 and $12 million and $42 million, respectively, for the three and nine months ended October 2, 2016.

The Company’s cost-method investments are assessed for impairment quarterly. The Company determines that it is not practicable to estimate the fair value of its cost-method investments on a regular basis and does not reassess the fair value of cost-method investments unless there are identified events or changes in circumstances that may have a significant adverse effect on the fair value of the investments. No material impairment losses were recorded during the three and nine months ended October 1, 2017 or October 2, 2016.

The Company invests in a venture capital investment fund (the Fund) with a capital commitment of $100 million that is callable over ten years. The Company’s investment in the Fund is accounted for as an equity method investment. The carrying amounts included in other assets were $14 million and $10 million as of October 1, 2017 and January 1, 2017, respectively.

Inventory

Inventory consists of the following (in millions):

	October 1, 2017		January 1, 2017
Raw materials	$	90	$	102
Work in process	192		161
Finished goods	45		37
Total inventory	$	327	$	300

11

Property and Equipment

Property and equipment, net consists of the following (in millions):

	October 1, 2017			January 1, 2017
Leasehold improvements	$	320		$	270
Machinery and equipment	301			274
Computer hardware and software	178			156
Furniture and fixtures	34			24
Building	147			9
Construction in progress	273			307
Total property and equipment, gross	1,253			1,040
Accumulated depreciation	(391		)	(327		)
Total property and equipment, net	$	862		$	713

Property and equipment, net included non-cash expenditures of $94 million and $194 million for the nine months ended October 1, 2017 and October 2, 2016, respectively, which were excluded from the condensed consolidated statements of cash flows. Such non-cash expenditures included $60 million and $169 million recorded under build-to-suit lease accounting for the nine months ended October 1, 2017 and October 2, 2016, respectively.

Intangible Assets and Goodwill

The Company tests the carrying value of goodwill in accordance with accounting rules on impairment of goodwill, which require the Company to estimate the fair value of the reporting unit annually, or when impairment indicators exist, and compare such amounts to their respective carrying values to determine if an impairment is required. The Company performed its annual assessment for goodwill impairment in the second quarter of 2017, noting no impairment.

Changes to the Company’s goodwill balance during the nine months ended October 1, 2017 are as follows (in millions):

	Goodwill
Balance as of January 1, 2017	$	776
GRAIL deconsolidation	(5		)
Balance as of October 1, 2017	$	771

The Company regularly performs reviews to determine if any event has occurred that may indicate its identifiable intangible assets are potentially impaired.  During the nine months ended October 1, 2017, the Company performed a recoverability test when the planned use of a finite-lived acquired intangible asset changed, resulting in an impairment charge of $18 million recorded in cost of product revenue. Also during the nine months ended October 1, 2017, the Company recorded a $5 million impairment charge of in-process research and development as it was determined the project had no future alternative use.

Derivatives

The Company is exposed to foreign exchange rate risks in the normal course of business. The Company enters into foreign exchange contracts to manage foreign currency risks related to monetary assets and liabilities that are denominated in currencies other than the U.S. dollar. These foreign exchange contracts are carried at fair value in other assets or other liabilities and are not designated as hedging instruments. Changes in the value of derivatives are recognized in other income, net, along with the remeasurement gain or loss on the foreign currency denominated assets or liabilities.

As of October 1, 2017, the Company had foreign exchange forward contracts in place to hedge exposures in the euro, Japanese yen, Australian dollar, and Canadian dollar. As of October 1, 2017 and January 1, 2017, the total notional amounts of outstanding forward contracts in place for foreign currency purchases were $79 million and $69 million, respectively.

12

Accrued Liabilities

Accrued liabilities consist of the following (in millions):

	October 1, 2017		January 1, 2017
Accrued compensation expenses	$	138	$	112
Deferred revenue, current portion	131		121
Accrued taxes payable	41		32
Customer deposits	18		20
Other	53		57
Total accrued liabilities	$	381	$	342

Warranties

The Company generally provides a one-year warranty on instruments. Additionally, the Company provides a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, the Company establishes an accrual for estimated warranty expenses based on historical experience as well as anticipated product performance. The Company periodically reviews its warranty reserve for adequacy and adjusts the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.

Changes in the Company’s reserve for product warranties during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	14		$	16		$	13		$	17
Additions charged to cost of product revenue	7			4			18			17
Repairs and replacements	(5		)	(6		)	(15		)	(20		)
Balance at end of period	$	16		$	14		$	16		$	14

Leases

Changes in the Company’s facility exit obligation related to its former headquarters lease during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	18		$	21		$	19		$	22
Accretion of interest expense	—			—			—			1
Cash payments	(1		)	(1		)	(2		)	(3		)
Balance at end of period	$	17		$	20		$	17		$	20

On February 22, 2017, the Company entered into a lease agreement for a building under construction in Madison, Wisconsin. Minimum lease payments during the initial 15-year term are estimated to be $46 million.

Investments in Consolidated Variable Interest Entities

GRAIL, Inc.

In January 2016, the Company obtained a majority equity ownership interest in GRAIL, a company formed with unrelated third party investors to develop a blood test for early-stage cancer detection. The Company determined that GRAIL

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was a variable interest entity as the entity lacked sufficient equity to finance its activities without additional support. Additionally, the Company determined that it had (a) control of GRAIL’s board of directors, which had unilateral power over the activities that most significantly impacted the economic performance of GRAIL and (b) the obligation to absorb losses of and the right to receive benefits from GRAIL that were potentially significant to GRAIL. As a result, the Company was deemed to be the primary beneficiary of GRAIL and was required to consolidate GRAIL.

In January 2016, GRAIL completed its Series A convertible preferred stock financing, raising $120 million, of which the Company invested $40 million. Additionally, the Company and GRAIL executed a long-term supply agreement in which the Company contributed certain perpetual licenses, employees, and discounted supply terms in exchange for 113 million shares of GRAIL’s Class B common stock. Such contributions were recorded at their historical basis as they remained within the control of the Company. The $80 million received by GRAIL from unrelated third party investors upon issuance of its Series A convertible preferred stock was classified as noncontrolling interests in stockholders’ equity on the Company’s condensed consolidated balance sheet.

In June 2016, GRAIL authorized for issuance 98 million shares of Series A-1 convertible preferred stock, all of which were issued to Illumina in exchange for Illumina’s 98 million shares of GRAIL Class B common stock. As a result of the exchange, Illumina recorded a $10 million deemed dividend, net of tax of $10 million, through equity, which was eliminated in consolidation.

Deconsolidation of GRAIL, Inc.

On February 28, 2017, GRAIL completed the initial close of its Series B preferred stock financing, raising over $900 million, in which the Company did not participate. Concurrent with the financing, GRAIL repurchased from the Company 35 million shares of its Series A preferred stock and approximately 34 million shares of its Series A-1 preferred stock for an aggregate purchase price of $278 million. At this time, the Company ceased to have a controlling financial interest in GRAIL and the Company’s equity ownership was reduced from 52% to 19%. Additionally, the Company’s voting interest was reduced to 13%, and the Company no longer has representation on GRAIL’s board of directors. As a result, the Company deconsolidated GRAIL’s financial statements effective February 28, 2017 and accounts for the remaining retained investment as a cost method investment. During the three months ended July 2, 2017, the Company purchased approximately 3 million Series B preferred shares for $14 million resulting in an ownership of approximately 17% of GRAIL’s outstanding stock and a 12% voting interest. As of October 1, 2017, the Company holds $185 million in other assets related to this investment, which consists of 5 million Series A preferred shares, and approximately 3 million Series B preferred shares and 78 million Class A common shares of GRAIL.

The operations of GRAIL from January 2, 2017 up to the date of deconsolidation are included in the accompanying condensed consolidated statements of income for the nine months ended October 1, 2017. During this period, the Company absorbed approximately 50% of GRAIL’s losses based upon its proportional ownership of GRAIL’s common stock.

On February 28, 2017, the Company recorded a pretax gain of $453 million included in other income, net, of which $159 million relates to the remeasurement of the Company’s retained equity interest to its fair value. The pretax gain on deconsolidation includes (i) the consideration received from GRAIL for its repurchase of a portion of the Company’s ownership interest, (ii) the derecognition of the carrying amounts of GRAIL’s assets and liabilities, (iii) the derecognition of the noncontrolling interest related to GRAIL, and (iv) the recording of the Company’s remaining interest in GRAIL at fair value. This fair value measurement of the Company’s remaining interest was derived using the market approach. Significant estimates and assumptions required for this valuation included, but were not limited to, various Black-Scholes option-pricing model assumptions as of the date of deconsolidation and estimated discounts for lack of marketability related to the equity securities. These unobservable inputs, which represent a Level 3 measurement, are supported by little or no market activity and reflect the Company’s own assumptions in measuring fair value. 

In connection with the deconsolidation of GRAIL, the parties amended their long-term supply agreement, including the discounted supply terms. The repurchase and supply arrangements, which were entered into concurrently, contain various elements and, as such, are deemed to be an arrangement with multiple deliverables as defined under the respective authoritative accounting guidance. The Company determined that each of the elements, which include the purchase obligation, the purchase right, and services to be provided in accordance with the long-term supply agreement, were at, or approximated, fair value on a standalone basis, and therefore, there was no discount to allocate among the deliverables. As such, none of the deconsolidation gain was allocated to these elements.

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Helix Holdings I, LLC

In July 2015, the Company obtained a 50% voting equity ownership interest in Helix Holdings I, LLC (Helix), a limited liability company formed with unrelated third party investors to pursue the development and commercialization of a marketplace for consumer genomics. The Company determined that Helix is a variable interest entity as the holders of the at-risk equity investments as a group lack the power to direct the activities of Helix that most significantly impact Helix’s economic performance. Additionally, the Company determined that it has (a) unilateral power over one of the activities that most significantly impacts the economic performance of Helix through its contractual arrangements and no one individual party has unilateral power over the remaining significant activities of Helix and (b) the obligation to absorb losses of and the right to receive benefits from Helix that are potentially significant to Helix. As a result, the Company is deemed to be the primary beneficiary of Helix and is required to consolidate Helix.

As contractually committed, the Company contributed certain perpetual licenses, instruments, intangibles, initial laboratory setup, and discounted supply terms in exchange for voting equity interests in Helix. Such contributions are recorded at their historical basis as they remain within the control of the Company. Helix is financed through cash contributions made by the third party investors in exchange for voting equity interests in Helix.

Certain noncontrolling Helix investors may require the Company to redeem all noncontrolling interests in cash at the then approximate fair market value. Such redemption right is exercisable at the option of certain noncontrolling interest holders after January 1, 2021, provided that a bona fide pursuit of the sale of Helix has occurred and an initial public offering of Helix has not been completed. The fair value of the redeemable noncontrolling interests is considered a Level 3 instrument.

As the contingent redemption is outside of the control of Illumina, the redeemable noncontrolling interests in Helix are classified outside of stockholders’ equity on the accompanying condensed consolidated balance sheets. The balance of the redeemable noncontrolling interests is reported at the greater of its carrying value after receiving its allocation of Helix’s profits and losses or its estimated redemption value at each reporting date. As of October 1, 2017, the noncontrolling shareholders and Illumina each held 50% of Helix’s outstanding voting equity interests.

The assets and liabilities of Helix are not significant to the Company’s financial position as of October 1, 2017. Helix has an immaterial impact on the Company’s condensed consolidated statements of income and cash flows for the three and nine months ended October 1, 2017.

As of October 1, 2017, the accompanying condensed consolidated balance sheet includes $32 million of cash and cash equivalents attributable to Helix that will be used to settle their respective obligations and will not be available to settle obligations of the Company.

Redeemable Noncontrolling Interests

The activity of the redeemable noncontrolling interests during the nine months ended October 1, 2017 is as follows (in millions):

	Redeemable Noncontrolling Interests
Balance as of January 1, 2017	$	44
Amount released from escrow	79
Vesting of redeemable equity awards	12
Net loss attributable to noncontrolling interests	(30		)
Adjustment up to the redemption value	30
Deconsolidation of GRAIL	(11		)
Balance as of October 1, 2017	$	124

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3. Fair Value Measurements

The following table presents the Company’s hierarchy for assets and liabilities measured at fair value on a recurring basis as of October 1, 2017 and January 1, 2017 (in millions):

	October 1, 2017								January 1, 2017
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Money market funds (cash equivalents)	$	1,051	$	—	$	—	$	1,051	$	386	$	—	$	—	$	386
Debt securities in government-sponsored entities	—		74		—		74		—		34		—		34
Corporate debt securities	—		342		—		342		—		476		—		476
U.S. Treasury securities	271		—		—		271		314		—		—		314
Deferred compensation plan assets	—		34		—		34		—		31		—		31
Total assets measured at fair value	$	1,322	$	450	$	—	$	1,772	$	700	$	541	$	—	$	1,241
Liabilities:
Acquisition related contingent consideration liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	4	$	4
Deferred compensation liability	—		31		—		31		—		29		—		29
Total liabilities measured at fair value	$	—	$	31	$	—	$	31	$	—	$	29	$	4	$	33

The Company holds available-for-sale securities that consist of highly liquid, investment grade debt securities. The Company considers information provided by the Company’s investment accounting and reporting service provider in the measurement of fair value of its debt securities. The investment service provider provides valuation information from an industry-recognized valuation service. Such valuations may be based on trade prices in active markets for identical assets or liabilities (Level 1 inputs) or valuation models using inputs that are observable either directly or indirectly (Level 2 inputs), such as quoted prices for similar assets or liabilities, yield curve, volatility factors, credit spreads, default rates, loss severity, current market and contractual prices for the underlying instruments or debt, broker and dealer quotes, as well as other relevant economic measures. The Company’s deferred compensation plan assets consist primarily of investments in life insurance contracts carried at cash surrender value, which reflects the net asset value of the underlying publicly traded mutual funds. The Company performs control procedures to corroborate the fair value of its holdings, including comparing valuations obtained from its investment service provider to valuations reported by the Company’s asset custodians, validation of pricing sources and models, and review of key model inputs if necessary.

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4. Debt

Summary of debt obligations

The Company’s debt obligations consist of the following (dollars in millions):

	October 1, 2017			January 1, 2017
Principal amount of 2019 Notes outstanding	$	633		$	633
Principal amount of 2021 Notes outstanding	517			517
Unamortized discount of liability component of convertible senior notes	(83		)	(105		)
Net carrying amount of liability component of convertible senior notes	1,067			1,045
Obligations under financing leases	111			9
Other	4			4
Less: current portion	(2		)	(2		)
Long-term debt	$	1,180		$	1,056
Carrying value of equity component of convertible senior notes, net of debt issuance cost	$	161		$	161
Fair value of convertible senior notes outstanding (Level 2)	$	1,262		$	1,108
Weighted-average remaining amortization period of discount on the liability component of convertible senior notes	3.0 years			3.6 years

Convertible Senior Notes

0% Convertible Senior Notes due 2019 (2019 Notes) and 0.5% Convertible Senior Notes due 2021 (2021 Notes)

In June 2014, the Company issued $633 million aggregate principal amount of 2019 Notes and $517 million aggregate principal amount of 2021 Notes. The Company used the net proceeds plus cash on hand to repurchase outstanding debt. The 2019 and 2021 Notes mature on June 15, 2019 and June 15, 2021, respectively, and the implied estimated effective rates of the liability components of the Notes were 2.9% and 3.5%, respectively, assuming no conversion.

Both the 2019 and 2021 Notes will be convertible into cash, shares of common stock, or a combination of cash and shares of common stock, at the Company's election, based on an initial conversion rate, subject to adjustment, of 3.9318 shares per $1,000 principal amount of the notes (which represents an initial conversion price of approximately $254.34 per share), only in the following circumstances and to the following extent: (1) during the five business-day period after any 10 consecutive trading day period (the measurement period) in which the trading price per 2019 and 2021 Note for each day of such measurement period was less than 98% of the product of the last reported sale price of the Company’s common stock and the conversion rate on each such day; (2) during any calendar quarter (and only during that quarter) after the calendar quarter ending September 30, 2014, if the last reported sale price of the Company’s common stock for 20 or more trading days in the period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter exceeds 130% of the applicable conversion price in effect on the last trading day of the immediately preceding calendar quarter; (3) upon the occurrence of specified events described in the indenture for the 2019 and 2021 Notes; and (4) at any time on or after March 15, 2019 for the 2019 Notes, or March 15, 2021 for the 2021 Notes, through the second scheduled trading day immediately preceding the maturity date.

Neither the 2019 nor the 2021 Notes were convertible as of October 1, 2017, and had no dilutive impact during the three and nine months ended October 1, 2017. If the 2019 and 2021 Notes were converted as of October 1, 2017, the if-converted value would not exceed the principal amount.

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0.25% Convertible Senior Notes due 2016

In 2011, the Company issued $920 million aggregate principal amount of 0.25% convertible senior notes due 2016 (2016 Notes) with a maturity date of March 15, 2016. The effective rate of the liability component was estimated to be 4.5%. Based upon meeting the stock trading price conversion requirement during the three months ended March 30, 2014, the 2016 Notes became convertible on April 1, 2014 through, and including, March 11, 2016. All notes were converted by March 11, 2016.

Build-to-suit leases

The Company evaluates whether it is the accounting owner of leased assets during the construction period when the Company is involved in the construction of leased assets. Including the Madison lease agreement entered on February 28, 2017, the Company is considered the owner of two construction projects for accounting purposes only under build-to-suit lease accounting due to certain indemnification obligations related to the construction. As of October 1, 2017 and January 1, 2017, the Company has recorded $124 million and $223 million, respectively, in project construction costs paid or reimbursed by the landlord as construction in progress and a corresponding build-to-suit lease liability.

During the nine months ended October 1, 2017, construction of a build-to-suit property was completed. The Company concluded it did not qualify for “sale-leaseback” treatment and the lease is accounted for as a financing obligation. Accordingly, the Company reclassified $102 million of construction in progress and build-to-suit lease liability to building asset and obligations under financing leases, respectively.

On February 28, 2017, the Company deconsolidated GRAIL, as further described in note “2. Balance Sheet Account Details”, and removed $58 million of construction in progress and the corresponding build-to-suit lease liability.

5. Share-based Compensation Expense

Share-based compensation expense for all stock awards consists of the following (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Cost of product revenue	$	3		$	2		$	9		$	6
Cost of service and other revenue	1			1			2			2
Research and development	12			12			38			33
Selling, general and administrative	18			20			74			61
Share-based compensation expense before taxes	34			35			123			102
Related income tax benefits	(11		)	(8		)	(34		)	(23		)
Share-based compensation expense, net of taxes	$	23		$	27		$	89		$	79

The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the Employee Stock Purchase Plan (ESPP) during the nine months ended October 1, 2017 are as follows:

	Employee Stock Purchase Rights
Risk-free interest rate	0.50% - 1.22%
Expected volatility	29% - 44%
Expected term	0.5 - 1.0 year
Expected dividends	0		%
Weighted-average fair value per share	$	46.85

As of October 1, 2017, approximately $242 million of unrecognized compensation cost related to restricted stock and ESPP shares granted to date is expected to be recognized over a weighted-average period of approximately 2.2 years.

6. Stockholders’ Equity

As of October 1, 2017, approximately 6.3 million shares remained available for future grants under the 2015 Stock Plan.

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Restricted Stock

The Company’s restricted stock activity and related information for the nine months ended October 1, 2017 is as follows (units in thousands):

	Restricted Stock Awards (RSA)		Restricted Stock Units (RSU)		Performance Stock Units (PSU)(1)		Weighted-Average Grant-Date Fair Value per Share
							RSA		RSU		PSU
Outstanding at January 1, 2017	32		2,293		460		$	136.30	$	141.80	$	158.66
Awarded	—		141		38		—		$	173.08	$	154.93
Vested	(11	)	(257	)	—		$	179.00	$	110.56	—
Cancelled	—		(184	)	(60	)	—		$	149.22	$	176.15
Outstanding at October 1, 2017	21		1,993		438		$	114.59	$	147.41	$	155.95

______________________________________

(1) The number of units reflect the estimated number of shares to be issued at the end of the performance period.

Stock Options

The Company’s stock option activity under all stock option plans during the nine months ended October 1, 2017 is as follows:

	Options (in thousands)		Weighted-Average Exercise Price
Outstanding at January 1, 2017	1,045		$	48.56
Exercised	(604	)	$	46.43
Outstanding and exercisable at October 1, 2017	441		$	51.51

Employee Stock Purchase Plan

The price at which common stock is purchased under the ESPP is equal to 85% of the fair market value of the common stock on the first day of the offering period or purchase date, whichever is lower. During the nine months ended October 1, 2017, approximately 0.3 million shares were issued under the ESPP. As of October 1, 2017, there were approximately 14.0 million shares available for issuance under the ESPP.

Share Repurchases

On July 28, 2016, the Company’s Board of Directors authorized a share repurchase program, which superseded all prior and available repurchase authorizations, to repurchase $250 million of outstanding common stock. During the three months ended April 2, 2017, the Company repurchased 0.6 million shares for $101 million, completing the share repurchase program.

On May 4, 2017, the Company’s Board of Directors authorized an additional share repurchase program to repurchase $250 million of outstanding common stock. The repurchases may be completed under a 10b5-1 plan or at management’s discretion. During the three months ended October 1, 2017, the Company repurchased 0.4 million shares for $75 million under a 10b5-1 plan. Authorizations to repurchase $175 million of the Company’s common stock remained available as of October 1, 2017.

7. Income Taxes

The Company’s effective tax rate may vary from the U.S. federal statutory tax rate due to the change in the mix of earnings in tax jurisdictions with different statutory rates, benefits related to tax credits, and the tax impact of non-deductible expenses and other permanent differences between income before income taxes and taxable income. The effective tax rates for the three and nine months ended October 1, 2017 were 12.9% and 24.3%, respectively. For the three and nine months ended October 1, 2017, the variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, and excess tax benefits related to share-based compensation. In addition, for the nine months ended October 1, 2017, the decrease from the federal statutory tax rate was partially offset by the discrete tax impact of $150 million from the gain on the deconsolidation of GRAIL.

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8. Legal Proceedings

The Company is involved in various lawsuits and claims arising in the ordinary course of business, including actions with respect to intellectual property, employment, and contractual matters. In connection with these matters, the Company assesses, on a regular basis, the probability and range of possible loss based on the developments in these matters. A liability is recorded in the financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. Because litigation is inherently unpredictable and unfavorable results could occur, assessing contingencies is highly subjective and requires judgments about future events. The Company regularly reviews outstanding legal matters to determine the adequacy of the liabilities accrued and related disclosures. The amount of ultimate loss may differ from these estimates. Each matter presents its own unique circumstances, and prior litigation does not necessarily provide a reliable basis on which to predict the outcome, or range of outcomes, in any individual proceeding. Because of the uncertainties related to the occurrence, amount, and range of loss on any pending litigation or claim, the Company is currently unable to predict their ultimate outcome, and, with respect to any pending litigation or claim where no liability has been accrued, to make a meaningful estimate of the reasonably possible loss or range of loss that could result from an unfavorable outcome. In the event that opposing litigants in outstanding litigations or claims ultimately succeed at trial and any subsequent appeals on their claims, any potential loss or charges in excess of any established accruals, individually or in the aggregate, could have a material adverse effect on the Company’s business, financial condition, results of operations, and/or cash flows in the period in which the unfavorable outcome occurs or becomes probable, and potentially in future periods.

9. Segment Information

The Company has two reportable segments: Core Illumina and one segment related to the combined activities of the Company’s consolidated VIEs, GRAIL and Helix (Consolidated VIEs). Following the GRAIL deconsolidation on February 28, 2017, the Company’s Consolidated VIEs no longer include GRAIL. The Company reports segment information based on the management approach. This approach designates the internal reporting used by the Chief Operating Decision Maker (“CODM”) for making decisions and assessing performance as the source of the Company’s reportable segments. The CODM allocates resources and assesses the performance of each operating segment using information about its revenues and income (losses) from operations. Based on the information used by the CODM, the Company has determined its reportable segments as follows:

Core Illumina:

Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina includes all operations of the Company, excluding the results of its consolidated VIEs.

Consolidated VIEs:

GRAIL:GRAIL was created to develop a blood test for early-stage cancer detection. GRAIL is currently in the early stages of developing this test and as such, had no revenues through the date of deconsolidation.

Helix: Helix was established to enable individuals to explore their genetic information by providing affordable sequencing and database services for consumers through third party partners, driving the creation of an ecosystem of consumer applications.

Management evaluates the performance of the Company’s operating segments based upon income (loss) from operations. The Company does not allocate expenses between segments. Core Illumina sells products and provides services to GRAIL and Helix in accordance with contractual agreements between the entities.

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The following table presents the operating performance of each reportable segment (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Revenues:
Core Illumina	$	715		$	615		$	1,978		$	1,792
Consolidated VIEs	1			—			4			—
Elimination of intersegment revenues	(2		)	(8		)	(7		)	(13		)
Consolidated revenues	$	714		$	607		$	1,975		$	1,779
Operating income (loss):
Core Illumina	$	203		$	191		$	447		$	502
Consolidated VIEs	(22		)	(25		)	(72		)	(50		)
Elimination of intersegment earnings	—			(5		)	1			(8		)
Consolidated operating income	$	181		$	161		$	376		$	444

The following table presents the total assets of each reportable segment (in millions):

	October 1, 2017			January 1, 2017
Total assets:
Core Illumina	$	4,999		$	4,167
Consolidated VIEs	59			180
Elimination of intersegment assets	(12		)	(66		)
Consolidated total assets	$	5,046		$	4,281

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

Our Management’s Discussion and Analysis of Financial Condition and Results of Operations (MD&A) will help readers understand our results of operations, financial condition, and cash flow. It is provided in addition to the accompanying condensed consolidated financial statements and notes. This MD&A is organized as follows:

• Business Overview and Outlook. High level discussion of our operating results and significant known trends that affect our business.

• Results of Operations. Detailed discussion of our revenues and expenses.

• Liquidity and Capital Resources. Discussion of key aspects of our statements of cash flows, changes in our financial position, and our financial commitments.

• Off-Balance Sheet Arrangements. We have no off-balance sheet arrangements.

• Critical Accounting Policies and Estimates. Discussion of significant changes since our most recent Annual Report on Form 10-K we believe are important to understanding the assumptions and judgments underlying our financial statements.

• Recent Accounting Pronouncements. Summary of recent accounting pronouncements applicable to our condensed consolidated financial statements.

This MD&A discussion contains forward-looking statements that involve risks and uncertainties. Please see “Consideration Regarding Forward-Looking Statements” at the end of this MD&A section for additional factors relating to such statements. This MD&A should be read in conjunction with our condensed consolidated financial statements and

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accompanying notes included in this report and our Annual Report on Form 10-K for the fiscal year ended January 1, 2017. Operating results are not necessarily indicative of results that may occur in future periods.

Business Overview and Outlook

This overview and outlook provides a high level discussion of our operating results and significant known trends that affect our business. We believe that an understanding of these trends is important to understanding our financial results for the periods being reported herein as well as our future financial performance. This summary is not intended to be exhaustive, nor is it intended to be a substitute for the detailed discussion and analysis provided elsewhere in this Quarterly Report on Form 10-Q.

About Illumina

The Company has two reportable segments: Illumina’s core operations (Core Illumina) and one segment related to the combined activities of the Company’s consolidated VIEs, GRAIL and Helix (Consolidated VIEs). Following the GRAIL deconsolidation on February 28, 2017, the Company’s Consolidated VIEs no longer include GRAIL. For information on GRAIL and Helix, refer to notes 2 and 9 of the Notes to the Condensed Consolidated Financial Statements provided in this Quarterly Report on Form 10-Q.

Our focus on innovation has established us as the global leader in sequencing- and array-based technologies for genetic analysis, serving customers in a wide range of markets, enabling the adoption of genomic solutions in research and clinical settings.

Our customers include leading genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, agrigenomics, commercial molecular diagnostic laboratories, and consumer genomics companies.

Our portfolio of integrated systems, consumables, and analysis tools is designed to accelerate and simplify genetic analysis. This portfolio addresses the range of genomic complexity, price points, and throughput, enabling customers to select the best solution for their research or clinical challenge.

Our financial results have been, and will continue to be, impacted by several significant trends, which are described below. While these trends are important to understanding and evaluating our financial results, this discussion should be read in conjunction with our condensed consolidated financial statements and the notes thereto in Item 1, Part I of this report, and the other transactions, events, and trends discussed in “Risk Factors” in Item 1A, Part II of this report and Item 1A of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017.

Next-Generation Sequencing

Next-generation sequencing has become an essential technology in our markets, and our portfolio of sequencing platforms represents a family of systems that are designed to meet the workflow, output, and accuracy demands of a full range of sequencing applications. We believe that the expanding sequencing market, along with an increase in the number of samples available and enhancements in our sequencing portfolio, will continue to drive demand for our next-generation sequencing technologies. As a result, we believe that our sequencing consumables revenue will continue to grow in future periods.

Arrays

As a complement to next-generation sequencing, we believe arrays offer a less expensive, faster, and highly accurate technology for use when genetic content is already known.  The information content of arrays is fixed and reproducible, providing a repeatable, standardized technology to read out subsets of nucleotide bases within the overall genome.  We believe that our customers, particularly in research, will migrate certain array studies to sequencing.  However, we expect that demand from customers in applied markets who require high-throughput, cost-effective screening solutions will provide growth.  Demand in the array market has trended toward more focused arrays that can be used on larger numbers of samples, resulting in a lower selling price per sample.

Financial Overview

Consolidated financial highlights for the first three quarters of 2017 include the following:

• Net revenue increased11% during the first three quarters of 2017 to $2.0 billion compared to $1.8 billion in the first three quarters of 2016 due to the growth in sales of our sequencing consumables and genotyping services, as well as the launch of our NovaSeq platform, partially offset by lower shipments of our HiSeq instruments. We expect our revenue to continue to increase in 2017.

• Gross profit as a percentage of revenue (gross margin) was 65.0% in the first three quarters of 2017 compared to 70.1% in the first three quarters of 2016. The gross margin decrease was driven by a variety of factors, including impairment of an acquired intangible asset, an increase in lower-margin array services mix, inventory reserves related to product transitions, and lower instrument margin from the NovaSeq introduction. Our gross margin in future periods will depend on several factors, including: market conditions that may impact our pricing power; sales mix changes among consumables, instruments, and services; product mix changes between established products and new products in new markets; excess and obsolete inventories; royalties; our cost structure for manufacturing operations relative to volume; and product support obligations.

• Income from operations as a percentage of revenue decreased to 19.0% in the first three quarters of 2017 compared to 25.0% in the first three quarters of 2016 primarily due to lower gross margins. We expect research and development and selling, general and administrative expenses to continue to grow.

• Our effective tax rate was 24.3% in the first three quarters of 2017 compared to 24.9% in the first three quarters of 2016. The variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, and excess tax benefits related to share-based compensation, partially offset by the discrete tax impact of $150 million from the gain on the deconsolidation of GRAIL. Our future effective tax rate may vary from the U.S. federal statutory tax rate due to the mix of earnings in tax jurisdictions with different statutory tax rates and the other factors discussed in the risk factor “We are subject to risks related to taxation in multiple jurisdictions” in Part I Item 1A of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017. We anticipate that our effective tax rate will trend lower than the U.S. federal statutory tax rate in the future due to the portion of our earnings that will be subject to lower statutory tax rates.

• Cash, cash equivalents, and short-term investments were $2.0 billion as of October 1, 2017, of which approximately $953 million was held by our foreign subsidiaries.

Results of Operations

To enhance comparability, the following table sets forth our unaudited condensed consolidated statements of income for the specified reporting periods stated as a percentage of total revenue.

	Q3 2017		Q3 2016		YTD 2017		YTD 2016
Revenue:
Product revenue	83.5	%	84.7	%	82.6	%	84.7	%
Service and other revenue	16.5		15.3		17.4		15.3
Total revenue	100.0		100.0		100.0		100.0
Cost of revenue:
Cost of product revenue	24.2		21.7		25.7		21.5
Cost of service and other revenue	7.0		6.3		7.7		6.6
Amortization of acquired intangible assets	1.3		1.8		1.6		1.8
Total cost of revenue	32.5		29.8		35.0		29.9
Gross profit	67.5		70.2		65.0		70.1
Operating expense:
Research and development	18.7		20.7		20.7		21.0
Selling, general and administrative	23.5		23.0		25.3		24.6

22

Legal contingencies	—		—		—		(0.5	)
Total operating expense	42.2		43.7		46.0		45.1
Income from operations	25.3		26.5		19.0		25.0
Other income (expense):
Interest income	0.6		0.3		0.7		0.4
Interest expense	(1.4	)	(1.3	)	(1.3	)	(1.5	)
Other income, net	—		—		23.1		0.1
Total other (expense) income, net	(0.8	)	(1.0	)	22.5		(1.0	)
Income before income taxes	24.5		25.5		41.5		24.0
Provision for income taxes	3.2		6.1		10.1		6.0
Consolidated net income	21.3		19.4		31.4		18.0
Add: Net loss attributable to noncontrolling interests	1.5		2.0		1.9		1.0
Net income attributable to Illumina stockholders	22.8	%	21.4	%	33.3	%	19.0	%

Percentages may not recalculate due to rounding

Our fiscal year is the 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. The three and nine month periods ended October 1, 2017 and October 2, 2016 were both 13 and 39 weeks, respectively.

Revenue

(Dollars in millions)	Q3 2017		Q3 2016		Change		% Change		YTD 2017		YTD 2016		Change		% Change
Product revenue	$	596	$	514	$	82	16	%	$	1,631	$	1,506	$	125	8	%
Service and other revenue	118		93		25		27		344		273		71		26
Total revenue	$	714	$	607	$	107	18	%	$	1,975	$	1,779	$	196	11	%

Product revenue consists primarily of revenue from sales of consumables and instruments. Service and other revenue consists primarily of sequencing and genotyping service revenue as well as instrument service contract revenue. Total revenue primarily relates to Core Illumina for all periods presented.

QTD 2017 vs. QTD 2016

Revenue increased $107 million, or 18%, to $714 million in Q3 2017 compared to $607 million in Q3 2016.

Consumables revenue increased$55 million, or 14%, to $451 million in Q3 2017 compared to $396 million in Q3 2016, driven by growth in the sequencing instrument installed base.

Instrument revenue increased$28 million, or 25%, to $140 million in Q3 2017 compared to $112 million in Q3 2016, primarily due to shipments of our NovaSeq instrument introduced in Q1 2017, partially offset by lower shipments of our HiSeq and HiSeq X instruments.

Service and other revenue increased $25 million, or 27%, to $118 million in Q3 2017 compared to $93 million in Q3 2016, driven by revenue from genotyping services and instrument service contracts associated with a larger sequencing installed base.

YTD 2017 vs. YTD 2016

Revenue increased$196 million, or 11%, to $1,975 million in the first three quarters of 2017 compared to $1,779 million in the first three quarters of 2016.

Consumables revenue increased$103 million, or 9%, to $1,240 million in the first three quarters of 2017 compared to $1,137 million in the first three quarters of 2016, driven by growth in the sequencing instrument installed base.

23

Instrument revenue increased$20 million, or 6%, to $376 million in the first three quarters of 2017 compared to $356 million in the first three quarters of 2016, primarily due to shipments of our NovaSeq instrument introduced in Q1 2017, partially offset by lower shipments of our HiSeq and HiSeq X instruments.

Service and other revenue increased$71 million, or 26%, to $344 million in the first three quarters of 2017 compared to $273 million in the first three quarters of 2016, driven by revenue from genotyping services and extended instrument service contracts associated with a larger sequencing installed base.

Gross Margin

(Dollars in millions)	Q3 2017			Q3 2016			Change		% Change	YTD 2017			YTD 2016			Change		% Change
Gross profit	$	482		$	426		$	56	13%	$	1,284		$	1,247		$	37	3%
Gross margin	67.5		%	70.2		%				65.0		%	70.1		%

QTD 2017 vs. QTD 2016

Gross margin decreased to 67.5% in Q3 2017 from 70.2% in Q3 2016. The gross margin decrease was primarily driven by an increase in lower-margin array services mix and lower instrument margin from the NovaSeq introduction.

YTD 2017 vs. YTD 2016

Gross margin decreased to 65.0% in the first three quarters of 2017 compared to 70.1% in the first three quarters of 2016. The gross margin decrease was driven by a variety of factors, including an $18 millionimpairment of an acquired intangible asset, an increase in lower-margin array services mix, inventory reserves related to product transitions, and lower instrument margin from the NovaSeq introduction.

Operating Expense

(Dollars in millions)	Q3 2017		Q3 2016		Change		% Change		YTD 2017		YTD 2016			Change		% Change
Research and development	$	134	$	126	$	8	6	%	$	409	$	374		$	35	9	%
Selling, general and administrative	167		139		28		20		499		438			61		14
Legal contingencies	—		—		—		—		—		(9		)	9		(100	)
Total operating expense	$	301	$	265	$	36	14	%	$	908	$	803		$	105	13	%

QTD 2017 vs. QTD 2016

Research and development (R&D) expense increased by $8 million, or 6%, in Q3 2017 from Q3 2016. Core Illumina R&D expense increased by $16 million, or 14%, in Q3 2017 from Q3 2016 primarily due to increased headcount. R&D expense of our Consolidated VIEs decreased by $8 million primarily due to the deconsolidation of GRAIL in Q1 2017, partially offset by higher headcount at Helix.

Selling, general and administrative (SG&A) expense increased by $28 million, or 20%, in Q3 2017 from Q3 2016. Core Illumina SG&A expense increased by $25 million, or 19%, in Q3 2017 from Q3 2016 primarily due to increased investment in headcount and facilities to support the continued growth and scale of our operations. SG&A expense of our Consolidated VIEs increased by $3 million due to marketing expenses related to Helix’s platform launch being offset by the deconsolidation of GRAIL in Q1 2017.

YTD 2017 vs. YTD 2016

Research and development expense increased by $35 million, or 9%, in the first three quarters of 2017 compared to the first three quarters of 2016. Core Illumina R&D expense increased by $41 million, or 12%, primarily due to increased headcount as we continue to invest in the development of new products as well as enhancements to existing products. R&D expense of our Consolidated VIEs decreased by $6 million primarily due to the deconsolidation of GRAIL in Q1 2017, partially offset by growth in Helix’s operations.

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Selling, general and administrative expense increased by $61 million, or 14%, in the first three quarters of 2017 compared to the first three quarters of 2016. Core Illumina SG&A expense increased by $42 million, or 10%, primarily due to increased headcount and facilities investment to support the continued growth and scale of our operations. SG&A expense of our Consolidated VIEs increased by $19 million due to marketing expenses related to Helix’s platform launch and increased headcount, as well as performance based compensation related to the GRAIL Series B financing. These results were partially offset by the deconsolidation of GRAIL in Q1 2017.

Legal contingencies in the first three quarters of 2016 represent a reversal of previously recorded expense related to the settlement of patent litigation.

Other (Expense) Income, Net

(Dollars in millions)	Q3 2017			Q3 2016			Change			% Change		YTD 2017			YTD 2016			Change			% Change
Interest income	$	4		$	2		$	2		100	%	$	13		$	7		$	6		86	%
Interest expense	(10		)	(9		)	(1		)	11		(26		)	(25		)	(1		)	4
Other income, net	—			—			—			—		457			1			456			45,600
Total other (expense) income, net	$	(6	)	$	(7	)	$	1		(14	)%	$	444		$	(17	)	$	461		(2,712	)%

Other (expense) income, net primarily relates to Core Illumina for all periods presented.

QTD 2017 vs. QTD 2016

Interest income increased in Q3 2017 compared to Q3 2016 as a result of higher yields on our investments and higher savings and money market balances. Interest expense consisted primarily of accretion of discount on our convertible senior notes.

YTD 2017 vs. YTD 2016

Interest income increased in the first three quarters of 2017 compared to the first three quarters of 2016 as a result of higher yields on our investments and higher savings and money market balances. Interest expense consisted primarily of accretion of discount on our convertible senior notes.

Other income, net in the first three quarters of 2017 primarily consists of a $453 million gain recorded on the deconsolidation of GRAIL. Other income, net in the first three quarters of 2016 primarily consisted of net foreign exchange gains and losses.

Provision for Income Taxes

(Dollars in millions)	Q3 2017			Q3 2016			Change			% Change		YTD 2017			YTD 2016			Change		% Change
Income before income taxes	$	175		$	154		$	21		14	%	$	820		$	427		$	393	92	%
Provision for income taxes	23			37			(14		)	(38	)	199			106			93		88
Consolidated net income	$	152		$	117		$	35		30	%	$	621		$	321		$	300	93	%
Effective tax rate	12.9		%	24.2		%						24.3		%	24.9		%

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QTD 2017 vs. QTD 2016

Our effective tax rate was 12.9% for Q3 2017 compared to 24.2% in Q3 2016. For Q3 2017, the variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, and excess tax benefits related to share-based compensation. For Q3 2016, the variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, partially offset by the tax impact associated with the investments in our consolidated variable interest entities.

YTD 2017 vs. YTD 2016

Our effective tax rate was 24.3% in the first three quarters of 2017 compared to 24.9% for the first three quarters of 2016. For the first three quarters of 2017, the variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, and excess tax benefits related to share-based compensation, partially offset by the discrete tax impact of $150 million from the gain on the deconsolidation of GRAIL. For the first three quarters of 2016, the variance from the U.S. federal statutory tax rate was primarily attributable to the mix of earnings in jurisdictions with lower statutory rates than the U.S. federal statutory rate, such as in Singapore and the United Kingdom, partially offset by the tax impact associated with the investments in our consolidated variable interest entities.

Liquidity and Capital Resources

At October 1, 2017, we had approximately $1.4 billion in cash and cash equivalents, of which approximately $708 million was held by our foreign subsidiaries. Cash and cash equivalents increased by $619 million from January 1, 2017, due to the factors described in the “Cash Flow Summary” below. Our primary source of liquidity, other than our holdings of cash, cash equivalents and investments, has been cash flows from operations. Our ability to generate cash from operations provides us with the financial flexibility we need to meet operating, investing, and financing needs. It is our intention to indefinitely reinvest all current and future foreign earnings in foreign subsidiaries.

Historically, we have liquidated our short-term investments and/or issued debt and equity securities to finance our business needs as a supplement to cash provided by operating activities. As of October 1, 2017, we had $687 million in short-term investments. Short-term investments held by our foreign subsidiaries as of October 1, 2017 were approximately $245 million. Our short-term investments include marketable securities consisting of U.S. government-sponsored entities, corporate debt securities, and U.S. Treasury securities.

We anticipate that our current cash, cash equivalents, and short-term investments, together with cash provided by operating activities are sufficient to fund our near term capital and operating needs for at least the next 12 months. Operating needs include the planned costs to operate our business, including amounts required to fund working capital and capital expenditures. Our primary short-term needs for capital, which are subject to change, include:

• support of commercialization efforts related to our current and future products, including expansion of our direct sales force and field support resources both in the United States and abroad;

• acquisitions of equipment and other fixed assets for use in our current and future manufacturing and research and development facilities;

• the continued advancement of research and development efforts;

• potential strategic acquisitions and investments;

• potential early repayment of debt obligations as a result of conversions;

• the expansion needs of our facilities, including costs of leasing and building out additional facilities; and

• repurchases of our outstanding common stock.

Our convertible senior notes due 2019 and 2021 were not convertible as of October 1, 2017.

During Q1 2017, we used $101 million to repurchase our outstanding shares, completing the stock repurchase program authorized by our Board of Directors on July 28, 2016. On May 4, 2017, the Board of Directors authorized an additional share repurchase program to repurchase $250 million of outstanding common stock. The repurchases may be completed under a

26

10b5-1 plan or at management’s discretion. During Q3 2017, we used $75 million to repurchase shares of our common stock under a 10b5-1 plan.

Certain noncontrolling Helix investors may require Illumina to redeem all noncontrolling interests in cash at the then approximate fair market value. Such redemption right is exercisable at the option of certain noncontrolling interest holders after January 1, 2021, provided that a bona fide pursuit of the sale of Helix has occurred and an initial public offering of Helix has not been completed. The fair value of the redeemable noncontrolling interests related to Helix as of October 1, 2017 was $124 million.

We have $86 million remaining in our capital commitment to the venture capital investment fund as of October 1, 2017.

We expect that our revenue and the resulting operating income, as well as the status of each of our new product development programs, will significantly impact our cash management decisions.

Our future capital requirements and the adequacy of our available funds will depend on many factors, including:

• our ability to successfully commercialize and further develop our technologies and create innovative products in our markets;

• scientific progress in our research and development programs and the magnitude of those programs;

• competing technological and market developments; and

• the need to enter into collaborations with other companies or acquire other companies or technologies to enhance or complement our product and service offerings.

Cash Flow Summary

(In millions)	YTD 2017			YTD 2016
Net cash provided by operating activities	$	581		$	517
Net cash provided by (used in) investing activities	101			(341		)
Net cash used in financing activities	(67		)	(151		)
Effect of exchange rate changes on cash and cash equivalents	4			1
Net increase in cash and cash equivalents	$	619		$	26

Operating Activities

Net cash provided by operating activities in the first three quarters of 2017 consisted of net income of $621 million less net adjustments of $116 million partially offset by net changes in operating assets and liabilities of $76 million. The primary non-cash adjustments to net income included the gain on deconsolidation of GRAIL of $453 million, depreciation and amortization expenses of $117 million, share-based compensation of $123 million, deferred income tax of $53 million, impairment of intangible assets of $23 million, and accretion of debt discount of $23 million. Cash flow impact from changes in net operating assets and liabilities were driven by increases in accrued liabilities, other long-term liabilities and inventory.

Net cash provided by operating activities in the first three quarters of 2016 consisted of net income of $321 million plus net adjustments of $290 million partially offset by net changes in operating assets and liabilities of $94 million. The primary non-cash expenses added back to net income included depreciation and amortization expenses of $103 million, share-based compensation of $102 million, deferred income tax of $58 million, and accretion of debt discount of $22 million. Cash flow impact from changes in net operating assets included increases in inventory and other assets, and a decrease in accrued liabilities and accounts payable, partially offset by an increase in other long-term liabilities, and decreases in accounts receivable and prepaid expenses.

Investing Activities

Net cash provided by investing activities totaled $101 million for the first three quarters of 2017. We purchased $359 million of available-for-sale securities and $495 million of our available-for-sale securities matured or were sold during the period. We received $278 million from the sale of a portion of our ownership interest in GRAIL. In connection with the sale, we removed $52 million in cash from our condensed consolidated balance sheet as a result of the deconsolidation. We paid $25 million for strategic investments and invested $234 million in capital expenditures, primarily associated with our investment in facilities.

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Net cash used in investing activities totaled $341 million for the first three quarters of 2016. We purchased $679 million of available-for-sale securities and $554 million of our available-for-sale securities matured or were sold during the period. We also paid net cash of $18 million for acquisitions and invested $178 million in capital expenditures primarily associated with facilities and the purchase of manufacturing, research, and development equipment.

Financing Activities

Net cash used in financing activities totaled $67 million for the first three quarters of 2017. We used $176 million to repurchase shares of our common stock and $28 million to pay taxes related to net share settlement of equity awards. We received $63 million in proceeds from issuance of common stock through the exercise of stock options and the sale of shares under our employee stock purchase plan, and contributions from noncontrolling interest owners were $79 million. Additionally, $7 million was used by Helix to repay financing obligations.

Net cash used in financing activities totaled $151 million for the first three quarters of 2016. We used $113 million to repurchase shares of our common stock, $76 million to pay taxes related to net share settlement of equity awards, $29 million to pay acquisition related contingent consideration, and $71 million to repay financing obligations. We received $47 million in proceeds from issuance of common stock through the exercise of stock options and the sale of shares under our employee stock purchase plan, $5 million in proceeds from issuance of debt related to an outstanding line of credit held by Helix, and $6 million in proceeds from early exercises of equity awards from a subsidiary. Contributions from noncontrolling owners were $80 million.

Off-Balance Sheet Arrangements

We do not participate in any transactions that generate relationships with unconsolidated entities or financial partnerships, such as entities often referred to as structured finance or special purpose entities, which would have been established for the purpose of facilitating off-balance sheet arrangements or other contractually narrow or limited purposes. During the first three quarters of 2017, we were not involved in any “off-balance sheet arrangements” within the meaning of the rules of the Securities and Exchange Commission.

Critical Accounting Policies and Estimates

In preparing our condensed consolidated financial statements, we make estimates, assumptions and judgments that can have a significant impact on our net revenue, operating income and net income, as well as on the value of certain assets and liabilities on our balance sheet. We believe that the estimates, assumptions and judgments involved in the accounting policies described in Management’s Discussion and Analysis of Financial Condition and Results of Operations in Item 7 of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017 have the greatest potential impact on our financial statements, so we consider them to be our critical accounting policies and estimates. Other than the adoption of ASU 2016-09, Compensation - Stock Compensation (Topic 718) as described in note 2 of the Notes to the Condensed Consolidated Financial Statements provided in this Quarterly Report on Form 10-Q, there were no material changes to our critical accounting policies and estimates during the first three quarters of 2017.

Recent Accounting Pronouncements

For summary of recent accounting pronouncements applicable to our condensed consolidated financial statements, see note “1. Summary of Significant Accounting Policies” in Part I, Item 1, Notes to Condensed Consolidated Financial Statements, which is incorporated herein by reference.

Consideration Regarding Forward-Looking Statements

This Quarterly Report on Form 10-Q contains forward-looking statements that involve risks and uncertainties, such as statements of our plans, strategies, objectives, expectations, intentions, and adequacy of resources. Words such as “anticipate,” “believe,” “continue,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” or similar words or phrases, or the negatives of these words, may identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward looking. Examples of forward-looking statements include, among others, statements regarding the integration of our acquired technologies with our existing technology, the commercial launch of new products, the entry into new business segments or markets, and the duration which our existing cash and other resources is expected to fund our operating activities.

28

Forward-looking statements are subject to known and unknown risks and uncertainties and are based on potentially inaccurate assumptions that could cause actual results to differ materially from those expected or implied by the forward-looking statements. Among the important factors that could cause actual results to differ materially from those in any forward-looking statements include the following:

• our ability to develop and commercialize our instruments and consumables, to deploy new products, services, and applications, and expand the markets for our technology platforms;

• our ability to manufacture robust instrumentation and consumables;

• our ability to identify and integrate acquired technologies, products, or businesses successfully;

• our expectations and beliefs regarding prospects and growth for the business and its markets;

• the assumptions underlying our critical accounting policies and estimates;

• our assessments and estimates that determine our effective tax rate;

• our assessments and beliefs regarding the outcome of pending legal proceedings and any liability that we may incur as a result of those proceedings;

• uncertainty, or adverse economic and business conditions, including as a result of slowing or uncertain economic growth in the United States or worldwide; and

• other factors detailed in our filings with the SEC, including the risks, uncertainties, and assumptions described in Item 1A of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017, or in information disclosed in public conference calls, the date and time of which are released beforehand.

The foregoing factors should be considered together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend to update these forward-looking statements, to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of the current financial quarter. Accordingly, you should not unduly rely on these forward-looking statements, which speak only as of the date of this Quarterly Report on Form 10-Q.

Item 3. Quantitative and Qualitative Disclosures About Market Risk.

There were no substantial changes to our market risks in the nine months ended October 1, 2017, when compared to the disclosures in Item 7A of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017.

Item 4. Controls and Procedures.

We design our internal controls to provide reasonable assurance that (1) our transactions are properly authorized; (2) our assets are safeguarded against unauthorized or improper use; and (3) our transactions are properly recorded and reported in conformity with U.S. generally accepted accounting principles. We also maintain internal controls and procedures to ensure that we comply with applicable laws and our established financial policies.

Based on management’s evaluation (under the supervision and with the participation of our chief executive officer (CEO) and chief financial officer (CFO)), as of the end of the period covered by this report, our CEO and CFO concluded that our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)), are effective to provide reasonable assurance that information required to be disclosed by us in reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in SEC rules and forms, and is accumulated and communicated to management, including our principal executive officer and principal financial officer, as appropriate, to allow timely decisions regarding required disclosure.

During Q3 2017, we continued to monitor and evaluate the operating effectiveness of key controls.  There were no changes in our internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) of the Exchange Act) that materially affected or are reasonably likely to materially affect internal control over financial reporting.

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PART II — OTHER INFORMATION

Item 1. Legal Proceedings.

We are involved in various lawsuits and claims arising in the ordinary course of business, including actions with respect to intellectual property, employment, and contractual matters. In connection with these matters, we assess, on a regular basis, the probability and range of possible loss based on the developments in these matters. A liability is recorded in the financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. Because litigation is inherently unpredictable and unfavorable results could occur, assessing contingencies is highly subjective and requires judgments about future events. We regularly review outstanding legal matters to determine the adequacy of the liabilities accrued and related disclosures. The amount of ultimate loss may differ from these estimates. Each matter presents its own unique circumstances, and prior litigation does not necessarily provide a reliable basis on which to predict the outcome, or range of outcomes, in any individual proceeding. Because of the uncertainties related to the occurrence, amount, and range of loss on any pending litigation or claim, we are currently unable to predict their ultimate outcome, and, with respect to any pending litigation or claim where no liability has been accrued, to make a meaningful estimate of the reasonably possible loss or range of loss that could result from an unfavorable outcome. In the event that opposing litigants or claims ultimately succeed at trial and any subsequent appeals on their claims, any potential loss or charges in excess of any established accruals, individually or in the aggregate, could have a material adverse effect on our business, financial condition, results of operations, and/or cash flows in the period in which the unfavorable outcome occurs or becomes probable, and potentially in future periods.

Item 1A. Risk Factors.

Our business is subject to various risks, including those described in Item 1A of our Annual Report on Form 10-K for the fiscal year ended January 1, 2017, which we strongly encourage you to review. There have been no material changes from the risk factors disclosed in Item 1A of our Form 10-K.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

Unregistered Sales of Equity Securities

None during the quarterly period ended October 1, 2017.

Purchases of Equity Securities by the Issuer

The following table summarizes shares repurchased pursuant to our share repurchase program during the three months ended October 1, 2017 (in thousands except for price per share):

Period	Total Number of Shares Purchased (1)	Average Price Paid per Share		Total Number of Shares Purchased as Part of Publicly Announced Programs	Approximate Dollar Value of Shares that May Yet Be Purchased Under the Programs
July 3, 2017 - July 30, 2017	—	—		—	$	250,001
July 31, 2017 - August 27, 2017	385	$	194.85	385	$	175,001
August 28, 2017 - October 1, 2017	—	—		—	$	175,001
Total	385	$	194.85	385	$	175,001

___________

(1) All shares purchased during the three months ended October 1, 2017, were made in open-market transactions under a Rule 10b5-1 plan.

Item 3. Defaults Upon Senior Securities.

None.

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Item 4. Mine Safety Disclosures.

Not applicable.

Item 5. Other Information.

None.

Item 6. Exhibits.

Exhibit Number	Description of Document
31.1	Certification of Francis A. deSouza pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
31.2	Certification of Sam A. Samad pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
32.1	Certification of Francis A. deSouza pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
32.2	Certification of Sam A. Samad pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
101.INS	XBRL Instance Document
101.SCH	XBRL Taxonomy Extension Schema
101.CAL	XBRL Taxonomy Extension Calculation Linkbase
101.LAB	XBRL Taxonomy Extension Label Linkbase
101.PRE	XBRL Taxonomy Extension Presentation Linkbase
101.DEF	XBRL Taxonomy Extension Definition Linkbase

31

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

		ILLUMINA, INC. (registrant)
Date:	October 25, 2017		/s/ SAM A. SAMAD
			Sam A. Samad Senior Vice President and Chief Financial Officer

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EX-31.1

Exhibit 31.1

CERTIFICATION OF FRANCIS A. DESOUZA PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Francis A. deSouza, certify that:

1	I have reviewed this Quarterly Report on Form 10-Q of Illumina, Inc.;
2	Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3	Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4	The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
	a)	designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
	b)	designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
	c)	evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
	d)	disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5	The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
	a)	all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
	b)	any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Dated: October 25, 2017

By:	/s/ FRANCIS A. DESOUZA
	Francis A. deSouza
	President and Chief Executive Officer

EX-31.2

Exhibit 31.2

CERTIFICATION OF SAM A. SAMAD PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Sam A. Samad, certify that:

1	I have reviewed this Quarterly Report on Form 10-Q of Illumina, Inc.;
2	Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3	Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4	The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
	a)	designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
	b)	designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
	c)	evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
	d)	disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5	The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
	a)	all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
	b)	any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Dated: October 25, 2017

By:	/s/ SAM A. SAMAD
	Sam A. Samad
	Senior Vice President and Chief Financial Officer

EX-32.1

Exhibit 32.1

CERTIFICATION OF FRANCIS A. DESOUZA PURSUANT TO 18 U.S.C. SECTION

1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-

OXLEY ACT OF 2002

In connection with the Quarterly Report of Illumina, Inc. (the “Company”) on Form 10-Q for the quarter ended October 1, 2017, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Francis A. deSouza, Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: October 25, 2017

By:	/s/ FRANCIS A. DESOUZA
	Francis A. deSouza
	President and Chief Executive Officer

This certification accompanying the Report is not deemed filed with the Securities and Exchange Commission for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities such Section, and is not to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before, on or after the date of the Report), irrespective of any general incorporation language contained in such filing.

EX-32.2

Exhibit 32.2

CERTIFICATION OF SAM A. SAMAD PURSUANT TO 18 U.S.C.

SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE

SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of Illumina, Inc. (the “Company”) on Form 10-Q for the quarter ended October 1, 2017, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Sam A. Samad, Senior Vice President and Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: October 25, 2017

By:	/s/ SAM A. SAMAD
	Sam A. Samad
	Senior Vice President and Chief Financial Officer

This certification accompanying the Report is not deemed filed with the Securities and Exchange Commission for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities such Section, and is not to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before, on or after the date of the Report), irrespective of any general incorporation language contained in such filing.

XML

Document and Entity Information - shares shares in Millions	9 Months Ended
	Oct. 01, 2017	Oct. 20, 2017
Document and Entity Information [Abstract]
Entity Registrant Name	Illumina Inc
Entity Central Index Key	0001110803
Current Fiscal Year End Date	--01-01
Entity Filer Category	Large Accelerated Filer
Document Type	10-Q
Document Period End Date	Oct. 01, 2017
Document Fiscal Year Focus	2017
Document Fiscal Period Focus	Q3
Amendment Flag	false
Entity Common Stock, Shares Outstanding		146

XML

Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Current assets:
Cash and cash equivalents	$ 1,354	$ 735
Short-term investments	687	824
Accounts receivable, net	383	381
Inventory	327	300
Prepaid expenses and other current assets	54	78
Total current assets	2,805	2,318
Property and equipment, net	862	713
Goodwill	771	776
Intangible assets, net	185	243
Deferred tax assets	117	123
Other assets	306	108
Total assets	5,046	4,281
Current liabilities:
Accounts payable	158	138
Accrued liabilities	381	342
Build-to-suit lease liability	124	223
Long-term debt, current portion	2	2
Total current liabilities	665	705
Long-term debt	1,180	1,056
Other long-term liabilities	222	206
Redeemable noncontrolling interests	124	44
Stockholders’ equity:
Common stock	2	2
Additional paid-in capital	2,891	2,733
Accumulated other comprehensive loss		(1)
Retained earnings	2,188	1,485
Treasury stock, at cost	(2,226)	(2,022)
Total Illumina stockholders' equity	2,855	2,197
Noncontrolling interests		73
Total stockholders’ equity	2,855	2,270
Total liabilities and stockholders’ equity	$ 5,046	$ 4,281

XML

Condensed Consolidated Statements of Income (Unaudited) - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Revenue:
Product revenue	$ 596	$ 514	$ 1,631	$ 1,506
Service and other revenue	118	93	344	273
Total revenue	714	607	1,975	1,779
Cost of revenue:
Cost of product revenue	173	132	508	383
Cost of service and other revenue	50	38	153	117
Amortization of acquired intangible assets	9	11	30	32
Total cost of revenue	232	181	691	532
Gross profit	482	426	1,284	1,247
Operating expense:
Research and development	134	126	409	374
Selling, general and administrative	167	139	499	438
Legal contingencies				(9)
Total operating expense	301	265	908	803
Income from operations	181	161	376	444
Other income (expense):
Interest income	4	2	13	7
Interest expense	(10)	(9)	(26)	(25)
Other income, net			457	1
Total other (expense) income, net	(6)	(7)	444	(17)
Income before income taxes	175	154	820	427
Provision for income taxes	23	37	199	106
Consolidated net income	152	117	621	321
Add: Net loss attributable to noncontrolling interests	11	12	37	18
Net income attributable to Illumina stockholders	163	129	658	339
Net income attributable to Illumina stockholders for earnings per share	$ 163	$ 129	$ 657	$ 336
Earnings per share attributable to Illumina stockholders:
Basic (in dollars per share)	$ 1.12	$ 0.88	$ 4.49	$ 2.29
Diluted (in dollars per share)	$ 1.11	$ 0.87	$ 4.45	$ 2.27
Shares used in computing earnings per common share:
Basic (in shares)	146	147	146	147
Diluted (in shares)	148	148	148	148

XML

Condensed Consolidated Statements of Comprehensive Income (Unaudited) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Statement of Comprehensive Income [Abstract]
Consolidated net income	$ 152	$ 117	$ 621	$ 321
Unrealized gain (loss) on available-for-sale securities, net of deferred tax	1	(1)	1	1
Total consolidated comprehensive income	153	116	622	322
Add: Comprehensive loss attributable to noncontrolling interests	11	12	37	18
Comprehensive income attributable to Illumina stockholders	$ 164	$ 128	$ 659	$ 340

XML

Condensed Consolidated Statement of Stockholders' Equity Statement - 9 months ended Oct. 01, 2017 - USD ($) $ in Millions	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive (Loss) Income [Member]	Retained Earnings [Member]	Treasury Stock [Member]	Noncontrolling Interests [Member]
Beginning balance at Jan. 01, 2017	$ 2,270	$ 2	$ 2,733	$ (1)	$ 1,485	$ (2,022)	$ 73
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net income (loss)	651				658		(7)
Unrealized gain on available-for-sale securities, net of deferred tax	1			1
Issuance of common stock, net of repurchases	(141)		63			(204)
Share-based compensation	123		123
Adjustment to the carrying value of redeemable noncontrolling interests	(30)		(30)
Vesting of redeemable equity awards	(12)		(12)
Cumulative-effect adjustment from adoption of ASU 2016-09	48		3		45
Deconsolidation of GRAIL	(55)		11				(66)
Ending balance at Oct. 01, 2017	$ 2,855	$ 2	$ 2,891	$ 0	$ 2,188	$ (2,226)	$ 0

XML

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Millions	9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016
Cash flows from operating activities:
Consolidated net income	$ 621	$ 321
Adjustments to reconcile net income to net cash provided by operating activities:
Gain on deconsolidation of GRAIL	(453)
Depreciation expense	81	65
Amortization of intangible assets	36	38
Share-based compensation expense	123	102
Accretion of debt discount	23	22
Deferred income taxes	53	58
Impairment of intangible assets	23
Other	(2)	5
Changes in operating assets and liabilities:
Accounts receivable	1	5
Inventory	(27)	(42)
Prepaid expenses and other current assets	14	3
Other assets	(3)	(6)
Accounts payable	12	(7)
Accrued liabilities	56	(57)
Other long-term liabilities	23	10
Net cash provided by operating activities	581	517
Cash flows from investing activities:
Purchases of available-for-sale securities	(359)	(679)
Sales of available-for-sale securities	314	406
Maturities of available-for-sale securities	181	148
Net cash paid for acquisitions		(18)
Proceeds from sale of GRAIL securities	278
Deconsolidation of GRAIL cash	(52)
Net purchases of strategic investments	(25)	(9)
Purchases of property and equipment	(234)	(178)
Cash paid for intangible assets	2	11
Net cash provided by (used in) investing activities	101	(341)
Cash flows from financing activities:
Payments on financing obligations	(7)	(71)
Payments on acquisition related contingent consideration liability	(3)	(29)
Proceeds from issuance of debt	5	5
Common stock repurchases	(176)	(113)
Taxes paid related to net share settlement of equity awards	(28)	(76)
Proceeds from issuance of common stock	63	47
Proceeds from early exercise of equity awards from a subsidiary		6
Contributions from noncontrolling interest owners	79	80
Net cash used in financing activities	(67)	(151)
Effect of exchange rate changes on cash and cash equivalents	4	1
Net increase in cash and cash equivalents	619	26
Cash and cash equivalents at beginning of period	735	769
Cash and cash equivalents at end of period	$ 1,354	$ 795

XML

Basis of Presentation and Summary of Significant Accounting Policies

9 Months Ended

Oct. 01, 2017

Accounting Policies [Abstract]

Basis of Presentation and Summary of Significant Accounting Policies

Basis of Presentation and Summary of Significant Accounting Policies

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (GAAP) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. Interim financial results are not necessarily indicative of results anticipated for the full year. These unaudited condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and footnotes included in the Company’s Annual Report on Form 10-K for the fiscal year ended January 1, 2017, from which the balance sheet information herein was derived. The preparation of financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expense, and related disclosure of contingent assets and liabilities. Actual results could differ from those estimates.

The unaudited condensed consolidated financial statements include the accounts of the Company, its wholly-owned subsidiaries, majority-owned or controlled companies, and variable interest entities (VIEs) for which the Company is the primary beneficiary. All intercompany transactions and balances have been eliminated in consolidation. Effective February 28, 2017, Illumina deconsolidated GRAIL, Inc.’s financial statements. In management’s opinion, the accompanying financial statements reflect all adjustments, consisting of normal recurring adjustments, considered necessary for a fair presentation of the results for the interim periods presented.

The Company evaluates its ownership, contractual, and other interests in entities that are not wholly-owned by the Company to determine if these entities are VIEs, and, if so, whether the Company is the primary beneficiary of the VIE. In determining whether the Company is the primary beneficiary of a VIE and is therefore required to consolidate the VIE, the Company applies a qualitative approach that determines whether it has both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may result in the consolidation or deconsolidation, as the case may be, of such VIE. The Company has not provided financial or other support during the periods presented to its VIEs that it was not previously contractually required to provide.

The equity method is used to account for investments in which the Company has the ability to exercise significant influence, but not control, over the investee. Such investments are recorded within other assets, and the share of net income or losses of equity investments is recognized on a one quarter lag in other income, net.

Redeemable Noncontrolling Interests

Noncontrolling interests represent the portion of equity (net assets) in a consolidated entity that is not wholly-owned by the Company that is not attributable, directly or indirectly, to the Company. Noncontrolling interests with embedded contingent redemption features, such as put rights, that are not solely within the Company’s control are considered redeemable noncontrolling interests. Redeemable noncontrolling interests are presented outside of stockholders’ equity on the condensed consolidated balance sheets.

Fiscal Year

The Company’s fiscal year consists of 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. The three and nine months ended October 1, 2017 and October 2, 2016 were both 13 and 39 weeks, respectively.

Reclassifications

Certain prior period amounts have been reclassified to conform to the current period presentation.

Significant Accounting Policies

During the three and nine months ended October 1, 2017, there have been no changes to the Company’s significant accounting policies as described in the Annual Report on Form 10-K for the fiscal year ended January 1, 2017.

Recently Adopted Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board issued Accounting Standard Update (ASU) 2016-09, Compensation - Stock Compensation (Topic 718), which aims to simplify the accounting for share-based payment transactions, including accounting for income taxes, classification on the statement of cash flows, accounting for forfeitures, and classification of awards as either liabilities or equity. This ASU was effective for the Company beginning in the first quarter of 2017.

Under the ASU, excess tax benefits from share-based payment arrangements are classified as discrete items within the provision for income taxes, rather than recognizing excess tax benefits in additional paid-in capital. Upon adoption in Q1 2017, the Company recorded $45 million, net, to retained earnings, primarily related to unrealized tax benefits associated with share-based compensation. During the three and nine months ended October 1, 2017, excess tax benefits of $12 million and $31 million, respectively, were reflected as a component of the provision for income taxes.

In addition, under the ASU, excess income tax benefits from share-based compensation arrangements are classified as cash flow from operations, rather than cash flow from financing activities. The Company has elected to apply the cash flow classification guidance retrospectively and reclassified $110 million from financing activity to operating activity for the nine months ended October 2, 2016.

Recently Issued Accounting Pronouncements

In May 2014, the Financial Accounting Standards Board issued Accounting Standards Update (ASU) 2014-09, Revenue from Contracts with Customers (Topic 606). The new standard is based on the principle that revenue should be recognized in an amount that reflects the consideration to which the entity expects to be entitled in exchange for the transfer of promised goods or services. Since its initial release, the FASB has issued several amendments to the standard, which include clarification of accounting guidance related to identification of performance obligations, intellectual property licenses, and principal vs. agent considerations.

ASU 2014-09 and all subsequent amendments (collectively, the “new standards”) will be effective for the Company beginning in the first quarter of 2018 and may be applied using either the full retrospective method, in which case the standard would be applied to each prior reporting period presented, or the modified retrospective method, in which case the cumulative effect of applying the standard would be recognized at the date of initial application.

The Company continues to work through steps in the implementation project plan, which include: finalizing new disclosures required by the new standards and implementing changes to business processes and reporting in support of the adoption of the new standards. The Company will adopt the new standards using the modified retrospective method with an adjustment to beginning retained earnings for the cumulative effect of the change, which is not expected to be material.

In January 2016, the Financial Accounting Standards Board issued ASU 2016-01, Financial Instruments - Overall (Subtopic 825-10), which requires equity investments (other than those accounted for under the equity method or those that result in consolidation) to be measured at fair value, with changes in fair value recognized in net income. ASU 2016-01 will be effective for the Company beginning in the first quarter of 2018. The Company anticipates that the adoption of ASU 2016-01 may increase the volatility of other income and expense, net, as a result of the remeasurement of the Company’s cost-method investments.

In February 2016, the Financial Accounting Standards Board issued ASU 2016-02, Leases (Topic 842). The new standard requires lessees to recognize most leases on their balance sheets as lease liabilities with corresponding right-of-use assets and eliminates certain real estate-specific provisions. ASU 2016-02 will be effective for the Company beginning in the first quarter of 2019. ASU 2016-02 will be adopted on a modified retrospective transition basis for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The Company is currently evaluating the impact of ASU 2016-02 on its consolidated financial statements.

In June 2016, the FASB issued ASU 2016-13, Financial Instruments - Credit Losses: Measurement of Credit Losses on Financial Instruments, which amends the impairment model by requiring entities to use a forward-looking approach based on expected losses to estimate credit losses on certain types of financial instruments, including trade receivables and available for sale debt securities. The ASU is effective for the Company beginning in the first quarter of 2020, with early adoption permitted.  The Company is currently evaluating the impact of ASU 2016-13 on its consolidated financial statements.

Earnings per Share

Basic earnings per share attributable to Illumina stockholders is computed based on the weighted average number of common shares outstanding during the period. Diluted earnings per share attributable to Illumina stockholders is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. Per-share earnings of our VIEs are included in the Company’s consolidated basic and diluted earnings per share computations based on the Company’s share of the VIEs’ securities.

Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. Convertible senior notes have a dilutive impact when the average market price of the Company’s common stock exceeds the applicable conversion price of the respective notes. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares. In loss periods, basic net loss per share and diluted net loss per share are identical because the otherwise dilutive potential common shares become anti-dilutive and are therefore excluded.

The following table presents the calculation of weighted average shares used to calculate basic and diluted earnings per share (in millions):

	Three Months Ended		Nine Months Ended
	October 1, 2017	October 2, 2016	October 1, 2017	October 2, 2016
Weighted average shares outstanding	146	147	146	147
Effect of potentially dilutive common shares from:
Equity awards	2	1	2	1
Weighted average shares used in calculating diluted earnings per share	148	148	148	148
Potentially dilutive shares excluded from calculation due to anti-dilutive effect	—	—	—	1

XML

Balance Sheet Account Details

9 Months Ended

Oct. 01, 2017

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Balance Sheet Account Details

Balance Sheet Account Details

Short-Term Investments

The following is a summary of short-term investments (in millions):

	October 1, 2017							January 1, 2017
	Amortized Cost		Gross Unrealized Losses			Estimated Fair Value		Amortized Cost		Gross Unrealized Losses			Estimated Fair Value
Available-for-sale securities:
Debt securities in government sponsored entities	$	74	$	—		$	74	$	34	$	—		$	34
Corporate debt securities	343		(1		)	342		478		(2		)	476
U.S. Treasury securities	272		(1		)	271		316		(2		)	314
Total available-for-sale securities	$	689	$	(2	)	$	687	$	828	$	(4	)	$	824

Realized gains and losses are determined based on the specific identification method and are reported in interest income.

Contractual maturities of available-for-sale debt securities as of October 1, 2017 were as follows (in millions):

	Estimated Fair Value
Due within one year	$	421
After one but within five years	266
Total	$	687

The Company has the ability, if necessary, to liquidate any of its cash equivalents and short-term investments in order to meet its liquidity needs in the next 12 months. Accordingly, those investments with contractual maturities greater than one year from the date of purchase nonetheless are classified as short-term on the accompanying condensed consolidated balance sheets.

Strategic Investments

As of October 1, 2017 and January 1, 2017, the aggregate carrying amounts of the Company’s cost-method investments in non-publicly traded companies included in other assets were $250 million and $57 million, respectively. Revenue recognized from transactions with such companies was $38 million and $96 million, respectively, for the three and nine months ended October 1, 2017 and $12 million and $42 million, respectively, for the three and nine months ended October 2, 2016.

The Company’s cost-method investments are assessed for impairment quarterly. The Company determines that it is not practicable to estimate the fair value of its cost-method investments on a regular basis and does not reassess the fair value of cost-method investments unless there are identified events or changes in circumstances that may have a significant adverse effect on the fair value of the investments. No material impairment losses were recorded during the three and nine months ended October 1, 2017 or October 2, 2016.

The Company invests in a venture capital investment fund (the Fund) with a capital commitment of $100 million that is callable over ten years. The Company’s investment in the Fund is accounted for as an equity method investment. The carrying amounts included in other assets were $14 million and $10 million as of October 1, 2017 and January 1, 2017, respectively.

Inventory

Inventory consists of the following (in millions):

	October 1, 2017		January 1, 2017
Raw materials	$	90	$	102
Work in process	192		161
Finished goods	45		37
Total inventory	$	327	$	300

Property and Equipment

Property and equipment, net consists of the following (in millions):

	October 1, 2017			January 1, 2017
Leasehold improvements	$	320		$	270
Machinery and equipment	301			274
Computer hardware and software	178			156
Furniture and fixtures	34			24
Building	147			9
Construction in progress	273			307
Total property and equipment, gross	1,253			1,040
Accumulated depreciation	(391		)	(327		)
Total property and equipment, net	$	862		$	713

Property and equipment, net included non-cash expenditures of $94 million and $194 million for the nine months ended October 1, 2017 and October 2, 2016, respectively, which were excluded from the condensed consolidated statements of cash flows. Such non-cash expenditures included $60 million and $169 million recorded under build-to-suit lease accounting for the nine months ended October 1, 2017 and October 2, 2016, respectively.

Intangible Assets and Goodwill

The Company tests the carrying value of goodwill in accordance with accounting rules on impairment of goodwill, which require the Company to estimate the fair value of the reporting unit annually, or when impairment indicators exist, and compare such amounts to their respective carrying values to determine if an impairment is required. The Company performed its annual assessment for goodwill impairment in the second quarter of 2017, noting no impairment.

Changes to the Company’s goodwill balance during the nine months ended October 1, 2017 are as follows (in millions):

	Goodwill
Balance as of January 1, 2017	$	776
GRAIL deconsolidation	(5		)
Balance as of October 1, 2017	$	771

The Company regularly performs reviews to determine if any event has occurred that may indicate its identifiable intangible assets are potentially impaired.  During the nine months ended October 1, 2017, the Company performed a recoverability test when the planned use of a finite-lived acquired intangible asset changed, resulting in an impairment charge of $18 million recorded in cost of product revenue. Also during the nine months ended October 1, 2017, the Company recorded a $5 million impairment charge of in-process research and development as it was determined the project had no future alternative use.

Derivatives

The Company is exposed to foreign exchange rate risks in the normal course of business. The Company enters into foreign exchange contracts to manage foreign currency risks related to monetary assets and liabilities that are denominated in currencies other than the U.S. dollar. These foreign exchange contracts are carried at fair value in other assets or other liabilities and are not designated as hedging instruments. Changes in the value of derivatives are recognized in other income, net, along with the remeasurement gain or loss on the foreign currency denominated assets or liabilities.

As of October 1, 2017, the Company had foreign exchange forward contracts in place to hedge exposures in the euro, Japanese yen, Australian dollar, and Canadian dollar. As of October 1, 2017 and January 1, 2017, the total notional amounts of outstanding forward contracts in place for foreign currency purchases were $79 million and $69 million, respectively.

Accrued Liabilities

Accrued liabilities consist of the following (in millions):

	October 1, 2017		January 1, 2017
Accrued compensation expenses	$	138	$	112
Deferred revenue, current portion	131		121
Accrued taxes payable	41		32
Customer deposits	18		20
Other	53		57
Total accrued liabilities	$	381	$	342

Warranties

The Company generally provides a one-year warranty on instruments. Additionally, the Company provides a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, the Company establishes an accrual for estimated warranty expenses based on historical experience as well as anticipated product performance. The Company periodically reviews its warranty reserve for adequacy and adjusts the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.

Changes in the Company’s reserve for product warranties during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	14		$	16		$	13		$	17
Additions charged to cost of product revenue	7			4			18			17
Repairs and replacements	(5		)	(6		)	(15		)	(20		)
Balance at end of period	$	16		$	14		$	16		$	14

Leases

Changes in the Company’s facility exit obligation related to its former headquarters lease during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	18		$	21		$	19		$	22
Accretion of interest expense	—			—			—			1
Cash payments	(1		)	(1		)	(2		)	(3		)
Balance at end of period	$	17		$	20		$	17		$	20

On February 22, 2017, the Company entered into a lease agreement for a building under construction in Madison, Wisconsin. Minimum lease payments during the initial 15-year term are estimated to be $46 million.

Investments in Consolidated Variable Interest Entities

GRAIL, Inc.

In January 2016, the Company obtained a majority equity ownership interest in GRAIL, a company formed with unrelated third party investors to develop a blood test for early-stage cancer detection. The Company determined that GRAIL was a variable interest entity as the entity lacked sufficient equity to finance its activities without additional support. Additionally, the Company determined that it had (a) control of GRAIL’s board of directors, which had unilateral power over the activities that most significantly impacted the economic performance of GRAIL and (b) the obligation to absorb losses of and the right to receive benefits from GRAIL that were potentially significant to GRAIL. As a result, the Company was deemed to be the primary beneficiary of GRAIL and was required to consolidate GRAIL.

In January 2016, GRAIL completed its Series A convertible preferred stock financing, raising $120 million, of which the Company invested $40 million. Additionally, the Company and GRAIL executed a long-term supply agreement in which the Company contributed certain perpetual licenses, employees, and discounted supply terms in exchange for 113 million shares of GRAIL’s Class B common stock. Such contributions were recorded at their historical basis as they remained within the control of the Company. The $80 million received by GRAIL from unrelated third party investors upon issuance of its Series A convertible preferred stock was classified as noncontrolling interests in stockholders’ equity on the Company’s condensed consolidated balance sheet.

In June 2016, GRAIL authorized for issuance 98 million shares of Series A-1 convertible preferred stock, all of which were issued to Illumina in exchange for Illumina’s 98 million shares of GRAIL Class B common stock. As a result of the exchange, Illumina recorded a $10 million deemed dividend, net of tax of $10 million, through equity, which was eliminated in consolidation.

Deconsolidation of GRAIL, Inc.

On February 28, 2017, GRAIL completed the initial close of its Series B preferred stock financing, raising over $900 million, in which the Company did not participate. Concurrent with the financing, GRAIL repurchased from the Company 35 million shares of its Series A preferred stock and approximately 34 million shares of its Series A-1 preferred stock for an aggregate purchase price of $278 million. At this time, the Company ceased to have a controlling financial interest in GRAIL and the Company’s equity ownership was reduced from 52% to 19%. Additionally, the Company’s voting interest was reduced to 13%, and the Company no longer has representation on GRAIL’s board of directors. As a result, the Company deconsolidated GRAIL’s financial statements effective February 28, 2017 and accounts for the remaining retained investment as a cost method investment. During the three months ended July 2, 2017, the Company purchased approximately 3 million Series B preferred shares for $14 million resulting in an ownership of approximately 17% of GRAIL’s outstanding stock and a 12% voting interest. As of October 1, 2017, the Company holds $185 million in other assets related to this investment, which consists of 5 million Series A preferred shares, and approximately 3 million Series B preferred shares and 78 million Class A common shares of GRAIL.

The operations of GRAIL from January 2, 2017 up to the date of deconsolidation are included in the accompanying condensed consolidated statements of income for the nine months ended October 1, 2017. During this period, the Company absorbed approximately 50% of GRAIL’s losses based upon its proportional ownership of GRAIL’s common stock.

On February 28, 2017, the Company recorded a pretax gain of $453 million included in other income, net, of which $159 million relates to the remeasurement of the Company’s retained equity interest to its fair value. The pretax gain on deconsolidation includes (i) the consideration received from GRAIL for its repurchase of a portion of the Company’s ownership interest, (ii) the derecognition of the carrying amounts of GRAIL’s assets and liabilities, (iii) the derecognition of the noncontrolling interest related to GRAIL, and (iv) the recording of the Company’s remaining interest in GRAIL at fair value. This fair value measurement of the Company’s remaining interest was derived using the market approach. Significant estimates and assumptions required for this valuation included, but were not limited to, various Black-Scholes option-pricing model assumptions as of the date of deconsolidation and estimated discounts for lack of marketability related to the equity securities. These unobservable inputs, which represent a Level 3 measurement, are supported by little or no market activity and reflect the Company’s own assumptions in measuring fair value. 

In connection with the deconsolidation of GRAIL, the parties amended their long-term supply agreement, including the discounted supply terms. The repurchase and supply arrangements, which were entered into concurrently, contain various elements and, as such, are deemed to be an arrangement with multiple deliverables as defined under the respective authoritative accounting guidance. The Company determined that each of the elements, which include the purchase obligation, the purchase right, and services to be provided in accordance with the long-term supply agreement, were at, or approximated, fair value on a standalone basis, and therefore, there was no discount to allocate among the deliverables. As such, none of the deconsolidation gain was allocated to these elements.

Helix Holdings I, LLC

In July 2015, the Company obtained a 50% voting equity ownership interest in Helix Holdings I, LLC (Helix), a limited liability company formed with unrelated third party investors to pursue the development and commercialization of a marketplace for consumer genomics. The Company determined that Helix is a variable interest entity as the holders of the at-risk equity investments as a group lack the power to direct the activities of Helix that most significantly impact Helix’s economic performance. Additionally, the Company determined that it has (a) unilateral power over one of the activities that most significantly impacts the economic performance of Helix through its contractual arrangements and no one individual party has unilateral power over the remaining significant activities of Helix and (b) the obligation to absorb losses of and the right to receive benefits from Helix that are potentially significant to Helix. As a result, the Company is deemed to be the primary beneficiary of Helix and is required to consolidate Helix.

As contractually committed, the Company contributed certain perpetual licenses, instruments, intangibles, initial laboratory setup, and discounted supply terms in exchange for voting equity interests in Helix. Such contributions are recorded at their historical basis as they remain within the control of the Company. Helix is financed through cash contributions made by the third party investors in exchange for voting equity interests in Helix.

Certain noncontrolling Helix investors may require the Company to redeem all noncontrolling interests in cash at the then approximate fair market value. Such redemption right is exercisable at the option of certain noncontrolling interest holders after January 1, 2021, provided that a bona fide pursuit of the sale of Helix has occurred and an initial public offering of Helix has not been completed. The fair value of the redeemable noncontrolling interests is considered a Level 3 instrument.

As the contingent redemption is outside of the control of Illumina, the redeemable noncontrolling interests in Helix are classified outside of stockholders’ equity on the accompanying condensed consolidated balance sheets. The balance of the redeemable noncontrolling interests is reported at the greater of its carrying value after receiving its allocation of Helix’s profits and losses or its estimated redemption value at each reporting date. As of October 1, 2017, the noncontrolling shareholders and Illumina each held 50% of Helix’s outstanding voting equity interests.

The assets and liabilities of Helix are not significant to the Company’s financial position as of October 1, 2017. Helix has an immaterial impact on the Company’s condensed consolidated statements of income and cash flows for the three and nine months ended October 1, 2017.

As of October 1, 2017, the accompanying condensed consolidated balance sheet includes $32 million of cash and cash equivalents attributable to Helix that will be used to settle their respective obligations and will not be available to settle obligations of the Company.

Redeemable Noncontrolling Interests

The activity of the redeemable noncontrolling interests during the nine months ended October 1, 2017 is as follows (in millions):

	Redeemable Noncontrolling Interests
Balance as of January 1, 2017	$	44
Amount released from escrow	79
Vesting of redeemable equity awards	12
Net loss attributable to noncontrolling interests	(30		)
Adjustment up to the redemption value	30
Deconsolidation of GRAIL	(11		)
Balance as of October 1, 2017	$	124

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Fair Value Measurements

9 Months Ended

Oct. 01, 2017

Fair Value Disclosures [Abstract]

Fair Value Measurements

Fair Value Measurements

The following table presents the Company’s hierarchy for assets and liabilities measured at fair value on a recurring basis as of October 1, 2017 and January 1, 2017 (in millions):

	October 1, 2017								January 1, 2017
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Money market funds (cash equivalents)	$	1,051	$	—	$	—	$	1,051	$	386	$	—	$	—	$	386
Debt securities in government-sponsored entities	—		74		—		74		—		34		—		34
Corporate debt securities	—		342		—		342		—		476		—		476
U.S. Treasury securities	271		—		—		271		314		—		—		314
Deferred compensation plan assets	—		34		—		34		—		31		—		31
Total assets measured at fair value	$	1,322	$	450	$	—	$	1,772	$	700	$	541	$	—	$	1,241
Liabilities:
Acquisition related contingent consideration liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	4	$	4
Deferred compensation liability	—		31		—		31		—		29		—		29
Total liabilities measured at fair value	$	—	$	31	$	—	$	31	$	—	$	29	$	4	$	33

The Company holds available-for-sale securities that consist of highly liquid, investment grade debt securities. The Company considers information provided by the Company’s investment accounting and reporting service provider in the measurement of fair value of its debt securities. The investment service provider provides valuation information from an industry-recognized valuation service. Such valuations may be based on trade prices in active markets for identical assets or liabilities (Level 1 inputs) or valuation models using inputs that are observable either directly or indirectly (Level 2 inputs), such as quoted prices for similar assets or liabilities, yield curve, volatility factors, credit spreads, default rates, loss severity, current market and contractual prices for the underlying instruments or debt, broker and dealer quotes, as well as other relevant economic measures. The Company’s deferred compensation plan assets consist primarily of investments in life insurance contracts carried at cash surrender value, which reflects the net asset value of the underlying publicly traded mutual funds. The Company performs control procedures to corroborate the fair value of its holdings, including comparing valuations obtained from its investment service provider to valuations reported by the Company’s asset custodians, validation of pricing sources and models, and review of key model inputs if necessary.

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Debt

9 Months Ended

Oct. 01, 2017

Debt Disclosure [Abstract]

Debt

Debt

Summary of debt obligations

The Company’s debt obligations consist of the following (dollars in millions):

	October 1, 2017			January 1, 2017
Principal amount of 2019 Notes outstanding	$	633		$	633
Principal amount of 2021 Notes outstanding	517			517
Unamortized discount of liability component of convertible senior notes	(83		)	(105		)
Net carrying amount of liability component of convertible senior notes	1,067			1,045
Obligations under financing leases	111			9
Other	4			4
Less: current portion	(2		)	(2		)
Long-term debt	$	1,180		$	1,056
Carrying value of equity component of convertible senior notes, net of debt issuance cost	$	161		$	161
Fair value of convertible senior notes outstanding (Level 2)	$	1,262		$	1,108
Weighted-average remaining amortization period of discount on the liability component of convertible senior notes	3.0 years			3.6 years

Convertible Senior Notes

0% Convertible Senior Notes due 2019 (2019 Notes) and 0.5% Convertible Senior Notes due 2021 (2021 Notes)

In June 2014, the Company issued $633 million aggregate principal amount of 2019 Notes and $517 million aggregate principal amount of 2021 Notes. The Company used the net proceeds plus cash on hand to repurchase outstanding debt. The 2019 and 2021 Notes mature on June 15, 2019 and June 15, 2021, respectively, and the implied estimated effective rates of the liability components of the Notes were 2.9% and 3.5%, respectively, assuming no conversion.

Both the 2019 and 2021 Notes will be convertible into cash, shares of common stock, or a combination of cash and shares of common stock, at the Company's election, based on an initial conversion rate, subject to adjustment, of 3.9318 shares per $1,000 principal amount of the notes (which represents an initial conversion price of approximately $254.34 per share), only in the following circumstances and to the following extent: (1) during the five business-day period after any 10 consecutive trading day period (the measurement period) in which the trading price per 2019 and 2021 Note for each day of such measurement period was less than 98% of the product of the last reported sale price of the Company’s common stock and the conversion rate on each such day; (2) during any calendar quarter (and only during that quarter) after the calendar quarter ending September 30, 2014, if the last reported sale price of the Company’s common stock for 20 or more trading days in the period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter exceeds 130% of the applicable conversion price in effect on the last trading day of the immediately preceding calendar quarter; (3) upon the occurrence of specified events described in the indenture for the 2019 and 2021 Notes; and (4) at any time on or after March 15, 2019 for the 2019 Notes, or March 15, 2021 for the 2021 Notes, through the second scheduled trading day immediately preceding the maturity date.

Neither the 2019 nor the 2021 Notes were convertible as of October 1, 2017, and had no dilutive impact during the three and nine months ended October 1, 2017. If the 2019 and 2021 Notes were converted as of October 1, 2017, the if-converted value would not exceed the principal amount.

0.25% Convertible Senior Notes due 2016

In 2011, the Company issued $920 million aggregate principal amount of 0.25% convertible senior notes due 2016 (2016 Notes) with a maturity date of March 15, 2016. The effective rate of the liability component was estimated to be 4.5%. Based upon meeting the stock trading price conversion requirement during the three months ended March 30, 2014, the 2016 Notes became convertible on April 1, 2014 through, and including, March 11, 2016. All notes were converted by March 11, 2016.

Build-to-suit leases

The Company evaluates whether it is the accounting owner of leased assets during the construction period when the Company is involved in the construction of leased assets. Including the Madison lease agreement entered on February 28, 2017, the Company is considered the owner of two construction projects for accounting purposes only under build-to-suit lease accounting due to certain indemnification obligations related to the construction. As of October 1, 2017 and January 1, 2017, the Company has recorded $124 million and $223 million, respectively, in project construction costs paid or reimbursed by the landlord as construction in progress and a corresponding build-to-suit lease liability.

During the nine months ended October 1, 2017, construction of a build-to-suit property was completed. The Company concluded it did not qualify for “sale-leaseback” treatment and the lease is accounted for as a financing obligation. Accordingly, the Company reclassified $102 million of construction in progress and build-to-suit lease liability to building asset and obligations under financing leases, respectively.

On February 28, 2017, the Company deconsolidated GRAIL, as further described in note “2. Balance Sheet Account Details”, and removed $58 million of construction in progress and the corresponding build-to-suit lease liability.

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Share-based Compensation Expense

9 Months Ended

Oct. 01, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Share-based Compensation Expense

Share-based Compensation Expense

Share-based compensation expense for all stock awards consists of the following (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Cost of product revenue	$	3		$	2		$	9		$	6
Cost of service and other revenue	1			1			2			2
Research and development	12			12			38			33
Selling, general and administrative	18			20			74			61
Share-based compensation expense before taxes	34			35			123			102
Related income tax benefits	(11		)	(8		)	(34		)	(23		)
Share-based compensation expense, net of taxes	$	23		$	27		$	89		$	79

The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the Employee Stock Purchase Plan (ESPP) during the nine months ended October 1, 2017 are as follows:

	Employee Stock Purchase Rights
Risk-free interest rate	0.50% - 1.22%
Expected volatility	29% - 44%
Expected term	0.5 - 1.0 year
Expected dividends	0		%
Weighted-average fair value per share	$	46.85

As of October 1, 2017, approximately $242 million of unrecognized compensation cost related to restricted stock and ESPP shares granted to date is expected to be recognized over a weighted-average period of approximately 2.2 years.

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Stockholders' Equity

9 Months Ended

Oct. 01, 2017

Equity [Abstract]

Stockholders' Equity

Stockholders’ Equity

As of October 1, 2017, approximately 6.3 million shares remained available for future grants under the 2015 Stock Plan.

Restricted Stock

The Company’s restricted stock activity and related information for the nine months ended October 1, 2017 is as follows (units in thousands):

	Restricted Stock Awards (RSA)		Restricted Stock Units (RSU)		Performance Stock Units (PSU)(1)		Weighted-Average Grant-Date Fair Value per Share
							RSA		RSU		PSU
Outstanding at January 1, 2017	32		2,293		460		$	136.30	$	141.80	$	158.66
Awarded	—		141		38		—		$	173.08	$	154.93
Vested	(11	)	(257	)	—		$	179.00	$	110.56	—
Cancelled	—		(184	)	(60	)	—		$	149.22	$	176.15
Outstanding at October 1, 2017	21		1,993		438		$	114.59	$	147.41	$	155.95

______________________________________

(1) The number of units reflect the estimated number of shares to be issued at the end of the performance period.

Stock Options

The Company’s stock option activity under all stock option plans during the nine months ended October 1, 2017 is as follows:

	Options (in thousands)		Weighted-Average Exercise Price
Outstanding at January 1, 2017	1,045		$	48.56
Exercised	(604	)	$	46.43
Outstanding and exercisable at October 1, 2017	441		$	51.51

Employee Stock Purchase Plan

The price at which common stock is purchased under the ESPP is equal to 85% of the fair market value of the common stock on the first day of the offering period or purchase date, whichever is lower. During the nine months ended October 1, 2017, approximately 0.3 million shares were issued under the ESPP. As of October 1, 2017, there were approximately 14.0 million shares available for issuance under the ESPP.

Share Repurchases

On July 28, 2016, the Company’s Board of Directors authorized a share repurchase program, which superseded all prior and available repurchase authorizations, to repurchase $250 million of outstanding common stock. During the three months ended April 2, 2017, the Company repurchased 0.6 million shares for $101 million, completing the share repurchase program.

On May 4, 2017, the Company’s Board of Directors authorized an additional share repurchase program to repurchase $250 million of outstanding common stock. The repurchases may be completed under a 10b5-1 plan or at management’s discretion. During the three months ended October 1, 2017, the Company repurchased 0.4 million shares for $75 million under a 10b5-1 plan. Authorizations to repurchase $175 million of the Company’s common stock remained available as of October 1, 2017.

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Income Taxes

9 Months Ended

Oct. 01, 2017

Income Tax Disclosure [Abstract]

Income Taxes

Income Taxes

The Company’s effective tax rate may vary from the U.S. federal statutory tax rate due to the change in the mix of earnings in tax jurisdictions with different statutory rates, benefits related to tax credits, and the tax impact of non-deductible expenses and other permanent differences between income before income taxes and taxable income. The effective tax rates for the three and nine months ended October 1, 2017 were 12.9% and 24.3%, respectively. For the three and nine months ended October 1, 2017, the variance from the U.S. federal statutory tax rate of 35% was primarily attributable to the mix of earnings in jurisdictions with lower statutory tax rates than the U.S. federal statutory tax rate, such as in Singapore and the United Kingdom, and excess tax benefits related to share-based compensation. In addition, for the nine months ended October 1, 2017, the decrease from the federal statutory tax rate was partially offset by the discrete tax impact of $150 million from the gain on the deconsolidation of GRAIL.

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Legal Proceedings

9 Months Ended

Oct. 01, 2017

Commitments and Contingencies Disclosure [Abstract]

Legal Proceedings

Legal Proceedings

The Company is involved in various lawsuits and claims arising in the ordinary course of business, including actions with respect to intellectual property, employment, and contractual matters. In connection with these matters, the Company assesses, on a regular basis, the probability and range of possible loss based on the developments in these matters. A liability is recorded in the financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. Because litigation is inherently unpredictable and unfavorable results could occur, assessing contingencies is highly subjective and requires judgments about future events. The Company regularly reviews outstanding legal matters to determine the adequacy of the liabilities accrued and related disclosures. The amount of ultimate loss may differ from these estimates. Each matter presents its own unique circumstances, and prior litigation does not necessarily provide a reliable basis on which to predict the outcome, or range of outcomes, in any individual proceeding. Because of the uncertainties related to the occurrence, amount, and range of loss on any pending litigation or claim, the Company is currently unable to predict their ultimate outcome, and, with respect to any pending litigation or claim where no liability has been accrued, to make a meaningful estimate of the reasonably possible loss or range of loss that could result from an unfavorable outcome. In the event that opposing litigants in outstanding litigations or claims ultimately succeed at trial and any subsequent appeals on their claims, any potential loss or charges in excess of any established accruals, individually or in the aggregate, could have a material adverse effect on the Company’s business, financial condition, results of operations, and/or cash flows in the period in which the unfavorable outcome occurs or becomes probable, and potentially in future periods.

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Segment Information (Notes)

9 Months Ended

Oct. 01, 2017

Segment Reporting [Abstract]

Segment Reporting Disclosure [Text Block]

Segment Information

The Company has two reportable segments: Core Illumina and one segment related to the combined activities of the Company’s consolidated VIEs, GRAIL and Helix (Consolidated VIEs). Following the GRAIL deconsolidation on February 28, 2017, the Company’s Consolidated VIEs no longer include GRAIL. The Company reports segment information based on the management approach. This approach designates the internal reporting used by the Chief Operating Decision Maker (“CODM”) for making decisions and assessing performance as the source of the Company’s reportable segments. The CODM allocates resources and assesses the performance of each operating segment using information about its revenues and income (losses) from operations. Based on the information used by the CODM, the Company has determined its reportable segments as follows:

Core Illumina:

Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina includes all operations of the Company, excluding the results of its consolidated VIEs.

Consolidated VIEs:

GRAIL:GRAIL was created to develop a blood test for early-stage cancer detection. GRAIL is currently in the early stages of developing this test and as such, had no revenues through the date of deconsolidation.

Helix: Helix was established to enable individuals to explore their genetic information by providing affordable sequencing and database services for consumers through third party partners, driving the creation of an ecosystem of consumer applications.

Management evaluates the performance of the Company’s operating segments based upon income (loss) from operations. The Company does not allocate expenses between segments. Core Illumina sells products and provides services to GRAIL and Helix in accordance with contractual agreements between the entities.

The following table presents the operating performance of each reportable segment (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Revenues:
Core Illumina	$	715		$	615		$	1,978		$	1,792
Consolidated VIEs	1			—			4			—
Elimination of intersegment revenues	(2		)	(8		)	(7		)	(13		)
Consolidated revenues	$	714		$	607		$	1,975		$	1,779
Operating income (loss):
Core Illumina	$	203		$	191		$	447		$	502
Consolidated VIEs	(22		)	(25		)	(72		)	(50		)
Elimination of intersegment earnings	—			(5		)	1			(8		)
Consolidated operating income	$	181		$	161		$	376		$	444

The following table presents the total assets of each reportable segment (in millions):

	October 1, 2017			January 1, 2017
Total assets:
Core Illumina	$	4,999		$	4,167
Consolidated VIEs	59			180
Elimination of intersegment assets	(12		)	(66		)
Consolidated total assets	$	5,046		$	4,281

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Basis of Presentation and Summary of Significant Accounting Policies (Policies)

9 Months Ended

Oct. 01, 2017

Accounting Policies [Abstract]

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (GAAP) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements.

Consolidation

The unaudited condensed consolidated financial statements include the accounts of the Company, its wholly-owned subsidiaries, majority-owned or controlled companies, and variable interest entities (VIEs) for which the Company is the primary beneficiary. All intercompany transactions and balances have been eliminated in consolidation. Effective February 28, 2017, Illumina deconsolidated GRAIL, Inc.’s financial statements. In management’s opinion, the accompanying financial statements reflect all adjustments, consisting of normal recurring adjustments, considered necessary for a fair presentation of the results for the interim periods presented.

Variable Interest Entities

The Company evaluates its ownership, contractual, and other interests in entities that are not wholly-owned by the Company to determine if these entities are VIEs, and, if so, whether the Company is the primary beneficiary of the VIE. In determining whether the Company is the primary beneficiary of a VIE and is therefore required to consolidate the VIE, the Company applies a qualitative approach that determines whether it has both (1) the power to direct the activities of the VIE that most significantly impact the VIE’s economic performance and (2) the obligation to absorb losses of, or the rights to receive benefits from, the VIE that could potentially be significant to that VIE. The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may result in the consolidation or deconsolidation, as the case may be, of such VIE. The Company has not provided financial or other support during the periods presented to its VIEs that it was not previously contractually required to provide.

Equity Method Investments

The equity method is used to account for investments in which the Company has the ability to exercise significant influence, but not control, over the investee. Such investments are recorded within other assets, and the share of net income or losses of equity investments is recognized on a one quarter lag in other income, net.

Redeemable Noncontrolling Interests

Noncontrolling interests represent the portion of equity (net assets) in a consolidated entity that is not wholly-owned by the Company that is not attributable, directly or indirectly, to the Company. Noncontrolling interests with embedded contingent redemption features, such as put rights, that are not solely within the Company’s control are considered redeemable noncontrolling interests. Redeemable noncontrolling interests are presented outside of stockholders’ equity on the condensed consolidated balance sheets.

Fiscal Year

The Company’s fiscal year consists of 52 or 53 weeks ending the Sunday closest to December 31, with quarters of 13 or 14 weeks ending the Sunday closest to March 31, June 30, September 30, and December 31. The three and nine months ended October 1, 2017 and October 2, 2016 were both 13 and 39 weeks, respectively.

Reclassifications

Certain prior period amounts have been reclassified to conform to the current period presentation.

Recently Adopted Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board issued Accounting Standard Update (ASU) 2016-09, Compensation - Stock Compensation (Topic 718), which aims to simplify the accounting for share-based payment transactions, including accounting for income taxes, classification on the statement of cash flows, accounting for forfeitures, and classification of awards as either liabilities or equity. This ASU was effective for the Company beginning in the first quarter of 2017.

Under the ASU, excess tax benefits from share-based payment arrangements are classified as discrete items within the provision for income taxes, rather than recognizing excess tax benefits in additional paid-in capital. Upon adoption in Q1 2017, the Company recorded $45 million, net, to retained earnings, primarily related to unrealized tax benefits associated with share-based compensation. During the three and nine months ended October 1, 2017, excess tax benefits of $12 million and $31 million, respectively, were reflected as a component of the provision for income taxes.

In addition, under the ASU, excess income tax benefits from share-based compensation arrangements are classified as cash flow from operations, rather than cash flow from financing activities. The Company has elected to apply the cash flow classification guidance retrospectively and reclassified $110 million from financing activity to operating activity for the nine months ended October 2, 2016.

Recently Issued Accounting Pronouncements

In May 2014, the Financial Accounting Standards Board issued Accounting Standards Update (ASU) 2014-09, Revenue from Contracts with Customers (Topic 606). The new standard is based on the principle that revenue should be recognized in an amount that reflects the consideration to which the entity expects to be entitled in exchange for the transfer of promised goods or services. Since its initial release, the FASB has issued several amendments to the standard, which include clarification of accounting guidance related to identification of performance obligations, intellectual property licenses, and principal vs. agent considerations.

ASU 2014-09 and all subsequent amendments (collectively, the “new standards”) will be effective for the Company beginning in the first quarter of 2018 and may be applied using either the full retrospective method, in which case the standard would be applied to each prior reporting period presented, or the modified retrospective method, in which case the cumulative effect of applying the standard would be recognized at the date of initial application.

The Company continues to work through steps in the implementation project plan, which include: finalizing new disclosures required by the new standards and implementing changes to business processes and reporting in support of the adoption of the new standards. The Company will adopt the new standards using the modified retrospective method with an adjustment to beginning retained earnings for the cumulative effect of the change, which is not expected to be material.

In January 2016, the Financial Accounting Standards Board issued ASU 2016-01, Financial Instruments - Overall (Subtopic 825-10), which requires equity investments (other than those accounted for under the equity method or those that result in consolidation) to be measured at fair value, with changes in fair value recognized in net income. ASU 2016-01 will be effective for the Company beginning in the first quarter of 2018. The Company anticipates that the adoption of ASU 2016-01 may increase the volatility of other income and expense, net, as a result of the remeasurement of the Company’s cost-method investments.

In February 2016, the Financial Accounting Standards Board issued ASU 2016-02, Leases (Topic 842). The new standard requires lessees to recognize most leases on their balance sheets as lease liabilities with corresponding right-of-use assets and eliminates certain real estate-specific provisions. ASU 2016-02 will be effective for the Company beginning in the first quarter of 2019. ASU 2016-02 will be adopted on a modified retrospective transition basis for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The Company is currently evaluating the impact of ASU 2016-02 on its consolidated financial statements.

In June 2016, the FASB issued ASU 2016-13, Financial Instruments - Credit Losses: Measurement of Credit Losses on Financial Instruments, which amends the impairment model by requiring entities to use a forward-looking approach based on expected losses to estimate credit losses on certain types of financial instruments, including trade receivables and available for sale debt securities. The ASU is effective for the Company beginning in the first quarter of 2020, with early adoption permitted.  The Company is currently evaluating the impact of ASU 2016-13 on its consolidated financial statements.

Earnings per Share

Basic earnings per share attributable to Illumina stockholders is computed based on the weighted average number of common shares outstanding during the period. Diluted earnings per share attributable to Illumina stockholders is computed based on the sum of the weighted average number of common shares and potentially dilutive common shares outstanding during the period. Per-share earnings of our VIEs are included in the Company’s consolidated basic and diluted earnings per share computations based on the Company’s share of the VIEs’ securities.

Potentially dilutive common shares consist of shares issuable under convertible senior notes and equity awards. Convertible senior notes have a dilutive impact when the average market price of the Company’s common stock exceeds the applicable conversion price of the respective notes. Potentially dilutive common shares from equity awards are determined using the average share price for each period under the treasury stock method. In addition, proceeds from exercise of equity awards and the average amount of unrecognized compensation expense for equity awards are assumed to be used to repurchase shares. In loss periods, basic net loss per share and diluted net loss per share are identical because the otherwise dilutive potential common shares become anti-dilutive and are therefore excluded.

Derivatives

The Company is exposed to foreign exchange rate risks in the normal course of business. The Company enters into foreign exchange contracts to manage foreign currency risks related to monetary assets and liabilities that are denominated in currencies other than the U.S. dollar. These foreign exchange contracts are carried at fair value in other assets or other liabilities and are not designated as hedging instruments. Changes in the value of derivatives are recognized in other income, net, along with the remeasurement gain or loss on the foreign currency denominated assets or liabilities.

Warranties

The Company generally provides a one-year warranty on instruments. Additionally, the Company provides a warranty on consumables through the expiration date, which generally ranges from six to twelve months after the manufacture date. At the time revenue is recognized, the Company establishes an accrual for estimated warranty expenses based on historical experience as well as anticipated product performance. The Company periodically reviews its warranty reserve for adequacy and adjusts the warranty accrual, if necessary, based on actual experience and estimated costs to be incurred. Warranty expense is recorded as a component of cost of product revenue.

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Basis of Presentation and Summary of Significant Accounting Policies (Tables)

9 Months Ended

Oct. 01, 2017

Accounting Policies [Abstract]

Summary of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings Per Share, Earnings Per Share

The following table presents the calculation of weighted average shares used to calculate basic and diluted earnings per share (in millions):

	Three Months Ended		Nine Months Ended
	October 1, 2017	October 2, 2016	October 1, 2017	October 2, 2016
Weighted average shares outstanding	146	147	146	147
Effect of potentially dilutive common shares from:
Equity awards	2	1	2	1
Weighted average shares used in calculating diluted earnings per share	148	148	148	148
Potentially dilutive shares excluded from calculation due to anti-dilutive effect	—	—	—	1

Summary of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings Per Share, Antidilutive Securities

The following table presents the calculation of weighted average shares used to calculate basic and diluted earnings per share (in millions):

	Three Months Ended		Nine Months Ended
	October 1, 2017	October 2, 2016	October 1, 2017	October 2, 2016
Weighted average shares outstanding	146	147	146	147
Effect of potentially dilutive common shares from:
Equity awards	2	1	2	1
Weighted average shares used in calculating diluted earnings per share	148	148	148	148
Potentially dilutive shares excluded from calculation due to anti-dilutive effect	—	—	—	1

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Balance Sheet Account Details (Tables)

9 Months Ended

Oct. 01, 2017

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Summary of Short-term Investments

The following is a summary of short-term investments (in millions):

	October 1, 2017							January 1, 2017
	Amortized Cost		Gross Unrealized Losses			Estimated Fair Value		Amortized Cost		Gross Unrealized Losses			Estimated Fair Value
Available-for-sale securities:
Debt securities in government sponsored entities	$	74	$	—		$	74	$	34	$	—		$	34
Corporate debt securities	343		(1		)	342		478		(2		)	476
U.S. Treasury securities	272		(1		)	271		316		(2		)	314
Total available-for-sale securities	$	689	$	(2	)	$	687	$	828	$	(4	)	$	824

Summary of Contractual Maturities of Available-for-sale Debt Securities

Contractual maturities of available-for-sale debt securities as of October 1, 2017 were as follows (in millions):

	Estimated Fair Value
Due within one year	$	421
After one but within five years	266
Total	$	687

Summary of Inventory

Inventory consists of the following (in millions):

	October 1, 2017		January 1, 2017
Raw materials	$	90	$	102
Work in process	192		161
Finished goods	45		37
Total inventory	$	327	$	300

Summary of Property and Equipment

Property and equipment, net consists of the following (in millions):

	October 1, 2017			January 1, 2017
Leasehold improvements	$	320		$	270
Machinery and equipment	301			274
Computer hardware and software	178			156
Furniture and fixtures	34			24
Building	147			9
Construction in progress	273			307
Total property and equipment, gross	1,253			1,040
Accumulated depreciation	(391		)	(327		)
Total property and equipment, net	$	862		$	713

Summary of Changes in Goodwill

Changes to the Company’s goodwill balance during the nine months ended October 1, 2017 are as follows (in millions):

	Goodwill
Balance as of January 1, 2017	$	776
GRAIL deconsolidation	(5		)
Balance as of October 1, 2017	$	771

Summary of Accrued Liabilities

Accrued liabilities consist of the following (in millions):

	October 1, 2017		January 1, 2017
Accrued compensation expenses	$	138	$	112
Deferred revenue, current portion	131		121
Accrued taxes payable	41		32
Customer deposits	18		20
Other	53		57
Total accrued liabilities	$	381	$	342

Summary of Changes in Reserve for Product Warranties

Changes in the Company’s reserve for product warranties during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	14		$	16		$	13		$	17
Additions charged to cost of product revenue	7			4			18			17
Repairs and replacements	(5		)	(6		)	(15		)	(20		)
Balance at end of period	$	16		$	14		$	16		$	14

Summary of Changes in Facility Exit Obligation Related to the Former Headquarters Lease

Changes in the Company’s facility exit obligation related to its former headquarters lease during the three and nine months ended October 1, 2017 and October 2, 2016 are as follows (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Balance at beginning of period	$	18		$	21		$	19		$	22
Accretion of interest expense	—			—			—			1
Cash payments	(1		)	(1		)	(2		)	(3		)
Balance at end of period	$	17		$	20		$	17		$	20

Summary of Activity of Redeemable Noncontrolling Interests

The activity of the redeemable noncontrolling interests during the nine months ended October 1, 2017 is as follows (in millions):

	Redeemable Noncontrolling Interests
Balance as of January 1, 2017	$	44
Amount released from escrow	79
Vesting of redeemable equity awards	12
Net loss attributable to noncontrolling interests	(30		)
Adjustment up to the redemption value	30
Deconsolidation of GRAIL	(11		)
Balance as of October 1, 2017	$	124

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Fair Value Measurements (Tables)

9 Months Ended

Oct. 01, 2017

Fair Value Disclosures [Abstract]

Summary of Hierarchy for Assets and Liabilities Measured at Fair Value on a Recurring Basis

The following table presents the Company’s hierarchy for assets and liabilities measured at fair value on a recurring basis as of October 1, 2017 and January 1, 2017 (in millions):

	October 1, 2017								January 1, 2017
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Money market funds (cash equivalents)	$	1,051	$	—	$	—	$	1,051	$	386	$	—	$	—	$	386
Debt securities in government-sponsored entities	—		74		—		74		—		34		—		34
Corporate debt securities	—		342		—		342		—		476		—		476
U.S. Treasury securities	271		—		—		271		314		—		—		314
Deferred compensation plan assets	—		34		—		34		—		31		—		31
Total assets measured at fair value	$	1,322	$	450	$	—	$	1,772	$	700	$	541	$	—	$	1,241
Liabilities:
Acquisition related contingent consideration liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	4	$	4
Deferred compensation liability	—		31		—		31		—		29		—		29
Total liabilities measured at fair value	$	—	$	31	$	—	$	31	$	—	$	29	$	4	$	33

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Debt (Tables)

9 Months Ended

Oct. 01, 2017

Debt Disclosure [Abstract]

Convertible Debt [Table Text Block]

Summary of debt obligations

The Company’s debt obligations consist of the following (dollars in millions):

	October 1, 2017			January 1, 2017
Principal amount of 2019 Notes outstanding	$	633		$	633
Principal amount of 2021 Notes outstanding	517			517
Unamortized discount of liability component of convertible senior notes	(83		)	(105		)
Net carrying amount of liability component of convertible senior notes	1,067			1,045
Obligations under financing leases	111			9
Other	4			4
Less: current portion	(2		)	(2		)
Long-term debt	$	1,180		$	1,056
Carrying value of equity component of convertible senior notes, net of debt issuance cost	$	161		$	161
Fair value of convertible senior notes outstanding (Level 2)	$	1,262		$	1,108
Weighted-average remaining amortization period of discount on the liability component of convertible senior notes	3.0 years			3.6 years

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Share-based Compensation Expense (Tables)

9 Months Ended

Oct. 01, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Summary of Share-based Compensation Expense for all Stock Awards

Share-based compensation expense for all stock awards consists of the following (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Cost of product revenue	$	3		$	2		$	9		$	6
Cost of service and other revenue	1			1			2			2
Research and development	12			12			38			33
Selling, general and administrative	18			20			74			61
Share-based compensation expense before taxes	34			35			123			102
Related income tax benefits	(11		)	(8		)	(34		)	(23		)
Share-based compensation expense, net of taxes	$	23		$	27		$	89		$	79

Summary of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan

The assumptions used for the specified reporting periods and the resulting estimates of weighted-average fair value per share for stock purchased under the Employee Stock Purchase Plan (ESPP) during the nine months ended October 1, 2017 are as follows:

	Employee Stock Purchase Rights
Risk-free interest rate	0.50% - 1.22%
Expected volatility	29% - 44%
Expected term	0.5 - 1.0 year
Expected dividends	0		%
Weighted-average fair value per share	$	46.85

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Stockholders' Equity (Tables)

9 Months Ended

Oct. 01, 2017

Equity [Abstract]

Summary of Restricted Stock Activity and Related Information, Restricted Stock

The Company’s restricted stock activity and related information for the nine months ended October 1, 2017 is as follows (units in thousands):

	Restricted Stock Awards (RSA)		Restricted Stock Units (RSU)		Performance Stock Units (PSU)(1)		Weighted-Average Grant-Date Fair Value per Share
							RSA		RSU		PSU
Outstanding at January 1, 2017	32		2,293		460		$	136.30	$	141.80	$	158.66
Awarded	—		141		38		—		$	173.08	$	154.93
Vested	(11	)	(257	)	—		$	179.00	$	110.56	—
Cancelled	—		(184	)	(60	)	—		$	149.22	$	176.15
Outstanding at October 1, 2017	21		1,993		438		$	114.59	$	147.41	$	155.95

______________________________________

(1) The number of units reflect the estimated number of shares to be issued at the end of the performance period.

Summary of Restricted Stock Activity and Related Information, Performance Units

The Company’s restricted stock activity and related information for the nine months ended October 1, 2017 is as follows (units in thousands):

	Restricted Stock Awards (RSA)		Restricted Stock Units (RSU)		Performance Stock Units (PSU)(1)		Weighted-Average Grant-Date Fair Value per Share
							RSA		RSU		PSU
Outstanding at January 1, 2017	32		2,293		460		$	136.30	$	141.80	$	158.66
Awarded	—		141		38		—		$	173.08	$	154.93
Vested	(11	)	(257	)	—		$	179.00	$	110.56	—
Cancelled	—		(184	)	(60	)	—		$	149.22	$	176.15
Outstanding at October 1, 2017	21		1,993		438		$	114.59	$	147.41	$	155.95

______________________________________

(1) The number of units reflect the estimated number of shares to be issued at the end of the performance period.

Summary of Stock Option Activity Under all Stock Option Plans

The Company’s stock option activity under all stock option plans during the nine months ended October 1, 2017 is as follows:

	Options (in thousands)		Weighted-Average Exercise Price
Outstanding at January 1, 2017	1,045		$	48.56
Exercised	(604	)	$	46.43
Outstanding and exercisable at October 1, 2017	441		$	51.51

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Segment Information (Tables)

9 Months Ended

Oct. 01, 2017

Segment Reporting [Abstract]

Summary of Operating Performance and Assets by Segment

The following table presents the operating performance of each reportable segment (in millions):

	Three Months Ended						Nine Months Ended
	October 1, 2017			October 2, 2016			October 1, 2017			October 2, 2016
Revenues:
Core Illumina	$	715		$	615		$	1,978		$	1,792
Consolidated VIEs	1			—			4			—
Elimination of intersegment revenues	(2		)	(8		)	(7		)	(13		)
Consolidated revenues	$	714		$	607		$	1,975		$	1,779
Operating income (loss):
Core Illumina	$	203		$	191		$	447		$	502
Consolidated VIEs	(22		)	(25		)	(72		)	(50		)
Elimination of intersegment earnings	—			(5		)	1			(8		)
Consolidated operating income	$	181		$	161		$	376		$	444

The following table presents the total assets of each reportable segment (in millions):

	October 1, 2017			January 1, 2017
Total assets:
Core Illumina	$	4,999		$	4,167
Consolidated VIEs	59			180
Elimination of intersegment assets	(12		)	(66		)
Consolidated total assets	$	5,046		$	4,281

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Basis of Presentation and Summary of Significant Accounting Policies - Narrative - Recently Adopted Accounting Principles (Details) - USD ($) $ in Millions	3 Months Ended	9 Months Ended
	Oct. 01, 2017	Oct. 01, 2017	Oct. 02, 2016	Apr. 02, 2017
Accounting Policies [Abstract]
Excess tax benefits from share-based compensation not yet recognized recorded in retained earnings				$ 45
Excess tax benefits from share-based compensation recorded in provision for income taxes	$ 12	$ 31
Excess tax benefits from share-based compensation recorded in operating activities			$ 110

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Basis of Presentation and Summary of Significant Accounting Policies - Summary of Calculation of Weighted Average Shares used to Calculate Basic and Diluted Earnings Per Share (Details) - shares shares in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Weighted average shares used to calculate basic and diluted earnings per share
Weighted average shares outstanding	146	147	146	147
Effect of potentially dilutive common shares from:
Equity awards	2	1	2	1
Weighted average shares used in calculating diluted earnings per share	148	148	148	148
Potentially dilutive shares excluded from calculation due to anti-dilutive effect				1

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Balance Sheet Account Details - Summary of Short-term Investments (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Available-for-sale securities:
Amortized Cost	$ 689	$ 828
Gross Unrealized Losses	(2)	(4)
Estimated Fair Value	687	824
Debt securities in government sponsored entities [Member]
Available-for-sale securities:
Amortized Cost	74	34
Estimated Fair Value	74	34
Corporate debt securities [Member]
Available-for-sale securities:
Amortized Cost	343	478
Gross Unrealized Losses	(1)	(2)
Estimated Fair Value	342	476
U.S. Treasury securities [Member]
Available-for-sale securities:
Amortized Cost	272	316
Gross Unrealized Losses	(1)	(2)
Estimated Fair Value	$ 271	$ 314

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Balance Sheet Account Details - Summary of Contractual Maturities of Available-for-sale Debt Securities (Details) $ in Millions	Oct. 01, 2017 USD ($)
Available-for-sale Securities, Debt Maturities, Fair Value, Fiscal Year Maturity [Abstract]
Due within one year	$ 421
After one but within five years	266
Total	$ 687

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Balance Sheet Account Details - Narrative - Strategic Investments (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016	Jan. 01, 2017
Schedule of Investments [Line Items]
Commitment in new venture capital investment fund	$ 100		$ 100
Callable period			10 years
Equity method investments	14		$ 14		$ 10
Cost-Method Investee [Member]
Schedule of Investments [Line Items]
Revenue from transactions with Company's cost-method investments in non-publicly traded companies	38	$ 12	96	$ 42
Other Assets [Member]
Schedule of Investments [Line Items]
Company's cost-method investments in non-publicly traded companies	$ 250		$ 250		$ 57

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Balance Sheet Account Details - Summary of Inventory (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Inventory [Abstract]
Raw materials	$ 90	$ 102
Work in process	192	161
Finished goods	45	37
Total inventory	$ 327	$ 300

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Balance Sheet Account Details - Summary of Property and Equipment (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 1,253	$ 1,040
Accumulated depreciation	(391)	(327)
Total property and equipment, net	862	713
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	320	270
Machinery and equipment
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	301	274
Computer hardware and software
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	178	156
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	34	24
Building
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	147	9
Construction in progress
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 273	$ 307

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Balance Sheet Account Details - Narrative - Property and Equipment (Details) - USD ($) $ in Millions	9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016
Property, Plant and Equipment [Line Items]
Non-cash expenditures included in capital expenditures	$ 94	$ 194
Construction in progress
Property, Plant and Equipment [Line Items]
Non-cash expenditures included in capital expenditures	$ 60	$ 169

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Balance Sheet Account Details - Summary of Changes in Goodwill (Details) $ in Millions	9 Months Ended
	Oct. 01, 2017 USD ($)
Goodwill [Roll Forward]
Beginning balance	$ 776
GRAIL deconsolidation	(5)
Ending balance	$ 771

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Balance Sheet Account Details - Narrative - Intangible Assets and Goodwill (Details) $ in Millions	9 Months Ended
	Oct. 01, 2017 USD ($)
Finite-Lived Intangible Assets [Line Items]
Impairment of in-process research and development	$ 5
Cost of Sales [Member]
Finite-Lived Intangible Assets [Line Items]
Impairment of finite-lived intangible assets	$ 18

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Balance Sheet Account Details - Narrative - Derivatives (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Not Designated as Hedging Instrument [Member] | Foreign Exchange Forward [Member]
Derivative [Line Items]
Derivative, notional amount	$ 79	$ 69

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Balance Sheet Account Details - Summary of Accrued Liabilities (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Accrued Liabilities, Current [Abstract]
Accrued compensation expenses	$ 138	$ 112
Deferred revenue, current portion	131	121
Accrued taxes payable	41	32
Customer deposits	18	20
Other	53	57
Total accrued liabilities	$ 381	$ 342

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Balance Sheet Account Details - Narrative - Warranties (Details)	9 Months Ended
	Oct. 01, 2017
Instruments [Member]
Product Warranty Liability [Line Items]
Warranty period	1 year
Consumables [Member] | Minimum [Member]
Product Warranty Liability [Line Items]
Warranty period	6 months
Consumables [Member] | Maximum [Member]
Product Warranty Liability [Line Items]
Warranty period	12 months

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Balance Sheet Account Details - Summary of Changes in Reserve for Product Warranties (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Reserve for product warranties [Roll Forward]
Balance at beginning of period	$ 14	$ 16	$ 13	$ 17
Additions charged to cost of product revenue	7	4	18	17
Repairs and replacements	(5)	(6)	(15)	(20)
Balance at end of period	$ 16	$ 14	$ 16	$ 14

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Balance Sheet Account Details - Summary of Changes in Facility Exit Obligation Related to the Former Headquarters Lease (Details) - Facility Exit Obligation [Member] - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Headquarter Facility Exit Obligation [Roll Forward]
Balance at beginning of period	$ 18	$ 21	$ 19	$ 22
Accretion of interest expense	0	0	0	1
Cash payments	(1)	(1)	(2)	(3)
Balance at end of period	$ 17	$ 20	$ 17	$ 20

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Balance Sheet Account Details - Narrative - Leases (Details) - February2017 Lease Agreements [Member] $ in Millions	Feb. 22, 2017 USD ($)
Lessee, Lease, Description [Line Items]
Finance lease term	15 years
Future minimum payment due for lease addition in period	$ 46

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Balance Sheet Account Details - Narrative - Investment in Consolidated Variable Interest Entities (Details) - USD ($) shares in Millions, $ in Millions		1 Months Ended		9 Months Ended
	Feb. 28, 2017	Jul. 03, 2016	Jan. 31, 2016	Oct. 01, 2017	Oct. 02, 2016	Feb. 27, 2017	Jan. 01, 2017	Jan. 03, 2016	Jul. 31, 2015
Variable Interest Entity [Line Items]
Contributions from noncontrolling interest owners				$ 79	$ 80
Noncontrolling shareholders interest percentage				50.00%
Cash and cash equivalents attributable to variable interest entities				$ 1,354	$ 795		$ 735	$ 769
Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Cash and cash equivalents attributable to variable interest entities				$ 32
GRAIL, Inc. [Member]
Variable Interest Entity [Line Items]
Deemed dividend		$ 10
Deemed dividend, tax effect		$ 10
GRAIL, Inc. [Member] | Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Series A financing			$ 120
Amount contributed			40
Contributions from noncontrolling interest owners			$ 80
Equity ownership interest percentage						52.00%
Helix Holdings I, LLC [Member] | Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Equity ownership interest percentage				50.00%					50.00%
GRAIL Class B [Member] | GRAIL, Inc. [Member] | Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Series A financing	$ 900
Stock exchanged (in shares)			113
GRAIL Class A-1 Convertible [Member] | GRAIL, Inc. [Member] | Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Shares authorized by GRAIL issued to Illumina		98
Illumina Class B [Member] | GRAIL, Inc. [Member] | Variable Interest Entity, Primary Beneficiary [Member]
Variable Interest Entity [Line Items]
Shares authorized by Illumina issued to GRAIL		98

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Balance Sheet Account Details - Narrative - Deconsolidation of GRAIL, Inc. (Details) - USD ($) shares in Millions, $ in Millions		1 Months Ended	2 Months Ended	3 Months Ended	9 Months Ended
	Feb. 28, 2017	Jan. 31, 2016	Feb. 28, 2017	Jul. 02, 2017	Oct. 01, 2017	Oct. 02, 2016	Feb. 27, 2017	Jan. 01, 2017
Variable Interest Entity [Line Items]
Proceeds from sale of GRAIL preferred stock					$ 278
Payments for additional GRAIL shares purchased by Illumina					25	$ 9
Gain on deconsolidation of GRAIL	$ 453				453
Portion of gain on deconsolidation related to remeasurement of Company's retained equity interest	$ 159
Other Assets [Member]
Variable Interest Entity [Line Items]
Cost-method investments					250			$ 57
GRAIL, Inc. [Member]
Variable Interest Entity [Line Items]
Cost-method investment ownership percentage	19.00%		19.00%	17.00%
Cost-method investment voting interest percentage	13.00%		13.00%	12.00%
GRAIL, Inc. [Member] | Other Assets [Member]
Variable Interest Entity [Line Items]
Cost-method investments					$ 185
GRAIL, Inc. [Member] | GRAIL Class B [Member]
Variable Interest Entity [Line Items]
Payments for additional GRAIL shares purchased by Illumina				$ 14
Additional GRAIL shares purchased by Illumina				3
Remaining shares of GRAIL owned by Illumina				3
GRAIL, Inc. [Member] | GRAIL Class A Preferred [Member]
Variable Interest Entity [Line Items]
Remaining shares of GRAIL owned by Illumina				5
GRAIL, Inc. [Member] | GRAIL Class A Common [Member]
Variable Interest Entity [Line Items]
Remaining shares of GRAIL owned by Illumina				78
Variable Interest Entity, Primary Beneficiary [Member] | GRAIL, Inc. [Member]
Variable Interest Entity [Line Items]
GRAIL Series B preferred financing		$ 120
Proceeds from sale of GRAIL preferred stock	$ 278
Equity ownership interest percentage							52.00%
Percentage of entity's losses absorbed			50.00%
Variable Interest Entity, Primary Beneficiary [Member] | GRAIL, Inc. [Member] | GRAIL Class B [Member]
Variable Interest Entity [Line Items]
GRAIL Series B preferred financing	$ 900
Variable Interest Entity, Primary Beneficiary [Member] | GRAIL, Inc. [Member] | GRAIL Class A Preferred [Member]
Variable Interest Entity [Line Items]
Shares repurchased by GRAIL from Illumina	35
Variable Interest Entity, Primary Beneficiary [Member] | GRAIL, Inc. [Member] | GRAIL Class A-1 Convertible [Member]
Variable Interest Entity [Line Items]
Shares repurchased by GRAIL from Illumina	34

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Balance Sheet Account Details - Summary of Activity of Redeemable Noncontrolling Interests (Details) $ in Millions	9 Months Ended
	Oct. 01, 2017 USD ($)
Increase (Decrease) in Redeemable Noncontrolling Interests [Roll Forward]
Balance as of January 1, 2017	$ 44
Amount released from escrow	79
Vesting of redeemable equity awards	12
Net loss attributable to noncontrolling interests	(30)
Adjustment up to the redemption value	30
Deconsolidation of GRAIL	(11)
Balance as of October 1, 2017	$ 124

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Fair Value Measurements - Summary of Hierarchy for Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Millions	Oct. 01, 2017	Jan. 01, 2017
Assets:
Available-for-sale securities	$ 687	$ 824
Debt securities in government sponsored entities [Member]
Assets:
Available-for-sale securities	74	34
Corporate debt securities [Member]
Assets:
Available-for-sale securities	342	476
U.S. Treasury securities [Member]
Assets:
Available-for-sale securities	271	314
Fair Value, Measurements, Recurring [Member]
Assets:
Deferred compensation plan assets	34	31
Total assets measured at fair value	1,772	1,241
Liabilities:
Acquisition related contingent consideration liabilities		4
Deferred compensation liability	31	29
Total liabilities measured at fair value	31	33
Fair Value, Measurements, Recurring [Member] | Debt securities in government sponsored entities [Member]
Assets:
Available-for-sale securities	74	34
Fair Value, Measurements, Recurring [Member] | Corporate debt securities [Member]
Assets:
Available-for-sale securities	342	476
Fair Value, Measurements, Recurring [Member] | U.S. Treasury securities [Member]
Assets:
Available-for-sale securities	271	314
Fair Value, Measurements, Recurring [Member] | Money market funds (cash equivalents) [Member]
Assets:
Money market funds (cash equivalents)	1,051	386
Fair Value, Measurements, Recurring [Member] | Level 1 [Member]
Assets:
Total assets measured at fair value	1,322	700
Fair Value, Measurements, Recurring [Member] | Level 1 [Member] | U.S. Treasury securities [Member]
Assets:
Available-for-sale securities	271	314
Fair Value, Measurements, Recurring [Member] | Level 1 [Member] | Money market funds (cash equivalents) [Member]
Assets:
Money market funds (cash equivalents)	1,051	386
Fair Value, Measurements, Recurring [Member] | Level 2 [Member]
Assets:
Deferred compensation plan assets	34	31
Total assets measured at fair value	450	541
Liabilities:
Deferred compensation liability	31	29
Total liabilities measured at fair value	31	29
Fair Value, Measurements, Recurring [Member] | Level 2 [Member] | Debt securities in government sponsored entities [Member]
Assets:
Available-for-sale securities	74	34
Fair Value, Measurements, Recurring [Member] | Level 2 [Member] | Corporate debt securities [Member]
Assets:
Available-for-sale securities	$ 342	476
Fair Value, Measurements, Recurring [Member] | Level 3 [Member]
Liabilities:
Acquisition related contingent consideration liabilities		4
Total liabilities measured at fair value		$ 4

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Debt - Summary of Information about Equity and Liability Components of Convertible Senior Notes Outstanding (Details) - USD ($) $ in Millions	9 Months Ended	12 Months Ended
	Oct. 01, 2017	Jan. 01, 2017	Jun. 29, 2014
Summarized information about equity and liability components of convertible senior notes
Obligations under financing leases	$ 111	$ 9
Other	4
Less: current portion	(2)	(2)
Long-term debt	1,180	1,056
Convertible Senior Notes [Member]
Summarized information about equity and liability components of convertible senior notes
Unamortized discount of liability component	(83)	(105)
Net carrying amount of liability component in long-term debt	1,067	1,045
Long-term debt	1,180	1,056
Carrying value of equity component, net of debt issuance cost	$ 161	$ 161
Weighted-average remaining amortization period of discount on the liability component	3 years	3 years 7 months
Fair Value, Inputs, Level 2 [Member] | Convertible Senior Notes [Member]
Summarized information about equity and liability components of convertible senior notes
Fair value of convertible senior notes outstanding (Level 2)	$ 1,262	$ 1,108
2019 Notes [Member] | Convertible Senior Notes [Member]
Summarized information about equity and liability components of convertible senior notes
Principal amount of notes outstanding	633	633	$ 633
2021 Notes [Member] | Convertible Senior Notes [Member]
Summarized information about equity and liability components of convertible senior notes
Principal amount of notes outstanding	$ 517	517	$ 517
Helix Holdings I, LLC [Member] | Line of Credit [Member]
Summarized information about equity and liability components of convertible senior notes
Other		$ 4

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Debt - Narrative (Details) - Convertible Senior Notes [Member] $ / shares in Units, $ in Millions	1 Months Ended	9 Months Ended
	Jun. 29, 2014 USD ($) $ / shares	Oct. 01, 2017 USD ($)	Jan. 01, 2017 USD ($)	Dec. 31, 2011 USD ($)
2019 Notes [Member]
Debt Instrument [Line Items]
Principal amount of notes outstanding	$ 633	$ 633	$ 633
Effective interest rate used to measure fair value of converted notes upon conversion	2.90%
Conversion rate	0.0039318
Conversion price (in dollars per share) | $ / shares	$ 254.34
Threshold note trading days		5
Threshold consecutive note trading days		10
Threshold percentage of note price trigger		98.00%
Threshold common stock trading days		20
Threshold consecutive common stock trading days		30
Threshold percentage of common stock price trigger		130.00%
2021 Notes [Member]
Debt Instrument [Line Items]
Principal amount of notes outstanding	$ 517	$ 517	$ 517
Effective interest rate used to measure fair value of converted notes upon conversion	3.50%
Conversion rate	0.0039318
Conversion price (in dollars per share) | $ / shares	$ 254.34
Threshold note trading days		5
Threshold consecutive note trading days		10
Threshold percentage of note price trigger		98.00%
Threshold common stock trading days		20
Threshold consecutive common stock trading days		30
Threshold percentage of common stock price trigger		130.00%
2016 Notes [Member]
Debt Instrument [Line Items]
Principal amount of notes outstanding				$ 920
Interest rate on convertible senior notes				0.25%
Effective interest rate used to measure fair value of converted notes upon conversion				4.50%

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Debt - Build-to-suit leases Narrative (Details) $ in Millions	Oct. 01, 2017 USD ($) Leases	Feb. 28, 2017 USD ($)	Jan. 01, 2017 USD ($)
Debt Instrument [Line Items]
Number of projects accounted for under build-to-suit lease accounting | Leases	2
Build-to-suit lease liability	$ 124		$ 223
Build-to-suit lease asset under construction	124		223
Obligations under financing leases	111		$ 9
Construction In Progress And Build to Suit Lease Liability [Member]
Debt Instrument [Line Items]
Obligations under financing leases	$ 102
GRAIL, Inc. [Member]
Debt Instrument [Line Items]
Build-to-suit lease liability		$ 58
Build-to-suit lease asset under construction		$ 58

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Share-based Compensation Expense - Summary of Share-based Compensation Expense for all Stock Awards (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016
Share-based Compensation
Share-based compensation expense before taxes	$ 34	$ 35	$ 123	$ 102
Related income tax benefits	(11)	(8)	(34)	(23)
Share-based compensation expense, net of taxes	23	27	89	79
Cost of product revenue [Member]
Share-based Compensation
Share-based compensation expense before taxes	3	2	9	6
Cost of service and other revenue [Member]
Share-based Compensation
Share-based compensation expense before taxes	1	1	2	2
Research and development [Member]
Share-based Compensation
Share-based compensation expense before taxes	12	12	38	33
Selling, general and administrative [Member]
Share-based Compensation
Share-based compensation expense before taxes	$ 18	$ 20	$ 74	$ 61

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Share-based Compensation Expense - Summary of Assumptions used to Estimate the Weighted-Average Fair Value Per Share for Stock Purchase under the Employee Stock Purchase Plan (Details) - Employee Stock [Member]	9 Months Ended
	Oct. 01, 2017 $ / shares
Assumptions used to estimate the fair value per share of employee stock purchase rights granted
Expected volatility, minimum	29.00%
Expected volatility, maximum	44.00%
Expected dividends	0.00%
Weighted-average fair value per share (in dollars per share)	$ 46.85
Minimum [Member]
Assumptions used to estimate the fair value per share of employee stock purchase rights granted
Risk-free interest rate	0.50%
Expected term	6 months
Maximum [Member]
Assumptions used to estimate the fair value per share of employee stock purchase rights granted
Risk-free interest rate	1.22%
Expected term	1 year

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Share-based Compensation Expense - Narrative (Details) $ in Millions	9 Months Ended
	Oct. 01, 2017 USD ($)
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Unrecognized compensation cost related to stock options, restricted stock, and ESPP shares granted to date	$ 242
Weighted-average period of unrecognized compensation cost related to stock options, restricted stock, and ESPP shares granted to date	2 years 2 months

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Stockholders' Equity - Narrative (Details) shares in Millions	Oct. 01, 2017 shares
2015 Illumina and 2005 Solexa Plans [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares available for issuance (in shares)	6.3

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Stockholders' Equity - Summary of Restricted Stock Activity and Related Information (Details) shares in Thousands	9 Months Ended
	Oct. 01, 2017 $ / shares shares
Restricted Stock Awards (RSA) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Outstanding at period start (in shares) | shares	32
Vested (in shares) | shares	(11)
Outstanding at period end (in shares) | shares	21
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value per Share, Outstanding at period start (in dollars per share) | $ / shares	$ 136.30
Weighted-Average Grant Date Fair Value per Share, Vested (in dollars per share) | $ / shares	179.00
Weighted-Average Grant Date Fair Value per Share, Outstanding at period end (in dollars per share) | $ / shares	$ 114.59
Restricted Stock Units (RSU) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Outstanding at period start (in shares) | shares	2,293
Awarded (in shares) | shares	141
Vested (in shares) | shares	(257)
Cancelled (in shares) | shares	(184)
Outstanding at period end (in shares) | shares	1,993
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value per Share, Outstanding at period start (in dollars per share) | $ / shares	$ 141.80
Weighted-Average Grant Date Fair Value per Share, Awarded (in dollars per share) | $ / shares	173.08
Weighted-Average Grant Date Fair Value per Share, Vested (in dollars per share) | $ / shares	110.56
Weighted-Average Grant Date Fair Value per Share, Cancelled (in dollars per share) | $ / shares	149.22
Weighted-Average Grant Date Fair Value per Share, Outstanding at period end (in dollars per share) | $ / shares	$ 147.41
Performance Stock Units (PSU) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Outstanding at period start (in shares) | shares	460
Awarded (in shares) | shares	38
Cancelled (in shares) | shares	(60)
Outstanding at period end (in shares) | shares	438
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value per Share, Outstanding at period start (in dollars per share) | $ / shares	$ 158.66
Weighted-Average Grant Date Fair Value per Share, Awarded (in dollars per share) | $ / shares	154.93
Weighted-Average Grant Date Fair Value per Share, Cancelled (in dollars per share) | $ / shares	176.15
Weighted-Average Grant Date Fair Value per Share, Outstanding at period end (in dollars per share) | $ / shares	$ 155.95

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Stockholders' Equity - Summary of Stock Option Activity Under all Stock Option Plans (Details) shares in Thousands	9 Months Ended
	Oct. 01, 2017 $ / shares shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Options, Outstanding at period start (in shares) | shares	1,045
Options, Exercised (in shares) | shares	(604)
Options, Outstanding at period end (in shares) | shares	441
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted-Average Exercise Price, Options, Outstanding at period start (in dollars per share) | $ / shares	$ 48.56
Weighted-Average Exercise Price, Options, Exercised (in dollars per share) | $ / shares	46.43
Weighted-Average Exercise Price, Options, Outstanding at period end (in dollars per share) | $ / shares	$ 51.51
Stock options exercisable (in shares) | shares	441
Stock options exercisable outstanding weighted-average exercise price per share (in dollars per share) | $ / shares	$ 51.51

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Stockholders' Equity - Narrative - Employee Stock Purchase Plan (Details) - ESPP [Member] - Employee Stock [Member] shares in Millions	9 Months Ended
	Oct. 01, 2017 shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Specified percentage of the fair market value of the common stock on the first or last day of the offering period whichever is lower at which stock is purchased	85.00%
Total shares issued under the ESPP (in shares)	0.3
Shares available for issuance (in shares)	14.0

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Stockholders' Equity - Narrative - Share Repurchases (Details) - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Apr. 02, 2017	Oct. 01, 2017	Oct. 02, 2016	May 04, 2017	Jul. 28, 2016
Class of Stock [Line Items]
Common stock repurchases			$ 176	$ 113
Common Stock [Member]
Class of Stock [Line Items]
Dollar amount remaining in authorized stock repurchase program	$ 175		$ 175
Common Stock [Member] | July 2016 Share Repurchase Plan [Member]
Class of Stock [Line Items]
Stock repurchase program, authorized amount						$ 250
Repurchase of common shares (in shares)		0.6
Common stock repurchases		$ 101
Common Stock [Member] | May 2017 Share Repurchase Plan [Member]
Class of Stock [Line Items]
Stock repurchase program, authorized amount					$ 250
Repurchase of common shares (in shares)	0.4
Common stock repurchases	$ 75

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Income Taxes - Narrative (Details) - USD ($) $ in Millions	3 Months Ended	9 Months Ended
	Oct. 01, 2017	Oct. 01, 2017
Income Tax Disclosure [Abstract]
Effective tax rate	12.90%	24.30%
U.S. federal statutory tax rate	35.00%	35.00%
Tax impact from the gain on the deconsolidation of GRAIL		$ 150

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Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Oct. 01, 2017	Oct. 02, 2016	Oct. 01, 2017	Oct. 02, 2016	Jan. 01, 2017
Segment Reporting Information [Line Items]
Segment revenues	$ 714	$ 607	$ 1,975	$ 1,779
Segment operating income (loss)	181	161	376	444
Segment assets	5,046		5,046		$ 4,281
Intersegment Eliminations
Segment Reporting Information [Line Items]
Segment revenues	(2)	(8)	(7)	(13)
Segment operating income (loss)		(5)	1	(8)
Segment assets	(12)		(12)		(66)
Operating Segments [Member] | Core Illumina
Segment Reporting Information [Line Items]
Segment revenues	715	615	1,978	1,792
Segment operating income (loss)	203	191	447	502
Segment assets	4,999		4,999		4,167
Operating Segments [Member] | Consolidated VIEs
Segment Reporting Information [Line Items]
Segment revenues	1		4
Segment operating income (loss)	(22)	$ (25)	(72)	$ (50)
Segment assets	$ 59		$ 59		$ 180