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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended 12 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Operating activities        
Net loss $ (8,192,745) $ (8,842,852) $ (18,105,315) $ (7,917,853)
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation and amortization 32,466 9,799 21,360 12,241
Stock-based compensation 2,491,451 1,471,780 4,463,695 604,976
Restricted stock issued for services 64,000 1,958,450 1,958,450 0
Change in fair value of warrants 0 (19,807) (19,807) (475,422)
Debt discount amortization 223,352 0    
Increase (decrease) in operating assets and liabilities:        
Grant receivable 757,562 (52,272) (673,218) (84,344)
Other receivables 0 (106,010) 2,275 28,316
Prepaid expenses and other 56,318 213,426 (199,377) (117,004)
Accounts payable (877,179) (331,501) 1,631,305 1,246,270
Accrued clinical operations and site costs 100,116 (134,569) (103,069) (279,413)
Related party liabilities     332,374 (789,014)
Accrued compensation (80,227) 220,857    
Other accrued expenses 199,752 307,090 166,145 109,228
Net cash used in operating activities (5,225,134) (5,305,609) (10,525,182) (7,662,019)
Investing activities        
Purchases of property and equipment (316,846) (35,154) (78,416) (44,807)
Proceeds from acquisition of Telik, Inc.     0 1,497,283
Net cash used in investing activities (316,846) (35,154) (78,416) 1,452,476
Financing activities        
Cash received from bank loan, net of financing costs 4,610,324 0    
Issuances of common stock, net of issuance costs 0 11,046,348 10,709,740 2,884,333
Issuances of preferred stock, net of issuance costs     2,500,000 2,973,655
Proceeds from exercise of MabVax Series B warrant     0 1,942
Proceeds from exercise of MabVax Series C-1 warrants     0 1,472,502
Proceeds from exercise of stock options 0 800 800 0
Principal payments on capital lease (2,555) 0    
Purchase of vested employee stock in connection with tax withholding obligation (177,823) 0    
Net cash provided by financing activities 4,429,946 11,047,148 13,210,540 7,332,432
Net change in cash and cash equivalents (1,112,034) 5,706,385 2,606,942 1,122,889
Cash and cash equivalents at beginning of period 4,084,085 1,477,143 1,477,143 354,254
Cash and cash equivalents at end of period 2,972,051 7,183,528 4,084,085 1,477,143
Supplemental disclosure:        
Cash paid during the period for income taxes 14,546 1,600 1,600 800
Supplemental disclosures of non-cash investing and financing information:        
Capital lease in connection with purchases of equipment 95,656 0    
Deemed dividend on beneficial conversion feature for preferred stock 0 17,852,921 17,852,921 2,214,911
Accretion of redemption value for Series A-1 and B preferred stock 0 93,234   444,992
Conversion of Series A-1 redeemable preferred stock into common stock 0 162,968 162,968 0
Conversion of Series C preferred stock to common stock 0 966 966 224
Conversion of Series B preferred stock to common stock 0 160,380    
Exchange of Series A-1 preferred stock and warrants into common stock and Series D preferred stock 0 13,111,280 160,380 12,527,124
Conversion of Series D preferred stock to common stock 0 400 467 0
Exchange of Series B preferred stock and warrants into common stock and Series D preferred stock 0 10,451,783    
Conversion of common stock to Series C preferred stock       1,190
Fair value of warrants issued 607,338 0    
Warrants exercised to purchase common stock on a cashless basis 0 12,198 12,198 4,887
Issuance of common stock for accounts payable     0 240,000
Conversion of Series A and Series B redeemable preferred stock into common stock $ 0 $ 13,111,280 160,380 12,527,124
Conversion of Series C-1 redeemable preferred stock into Series A-1 preferred stock     0 6,807,388
Goodwill on acquisition of Telik, Inc.     0 6,826,003
Warrant liability upon acquisition of Telik, Inc.     0 567,885
Acquisition of MabVax Therapeutics Holdings in relation to the merger     0 4,705,726
Elimination of warrant liability in exchange transaction     72,656 0
Financing transaction not yet paid     36,570 0
Property and equipment accrued in accounts payable     $ 21,376