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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Revenues:            
Grants $ 0 $ 136,616 $ 148,054 $ 376,156 $ 1,267,036 $ 304,175
Other         0 10,000
Total revenues 0 136,616 148,054 376,156 1,267,036 314,175
Operating costs and expenses:            
Research and development 1,596,002 2,325,637 3,296,514 4,051,530 9,596,768 3,502,730
General and administrative 1,929,166 4,206,512 4,581,005 5,187,101 9,795,163 5,204,341
Total operating costs and expenses 3,525,168 6,532,149 7,877,519 9,238,631 19,391,931 8,707,071
Loss from operations (3,525,168) (6,395,533) (7,729,465) (8,862,475) (18,124,895) (8,392,896)
Interest and other income (expense) (262,807) 0 (463,280) (184) (227) (379)
Change in fair value of warrant liability 0 0 0 19,807 19,807 475,422
Net loss (3,787,975) (6,395,533) (8,192,745) (8,842,852) (18,105,315) (7,917,853)
Deemed dividend on Series A-1 preferred stock 0 0 0 (9,017,512) (9,017,512) (2,214,911)
Deemed dividend on Series A-1 warrant 0 0 0 (179,411) (179,411) 0
Deemed dividend on Series B preferred stock 0 0 0 (8,655,998) (8,655,998) 0
Accretion of preferred stock dividends 0 0 0 (93,234) (93,234) (444,992)
Net loss allocable to common stockholders $ (3,787,975) $ (6,395,533) $ (8,192,745) $ (26,789,007) $ (36,051,470) $ (10,577,756)
Basic and diluted net loss per share $ (.92) $ (2.18) $ (2.03) $ (15.82) $ (13.44) $ (70.36)
Shares used to calculate basic and diluted net loss per share 4,128,617 2,931,811 4,037,834 1,693,233 2,681,740 150,336